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Modelling the potential impact of global warming on Ips typographus voltinism and reproductive diapause

The Eurasian spruce bark beetle, Ips typographus, is one of the major forest insect pests in Europe, capable of mass-attacking and killing mature Norway spruce trees. The initiation and development of a new generation are strongly controlled by temperature and a warmer climate may affect the number of generations that is produced per year and hence the outbreak dynamics. Experimental knowledge reg

Experimental studies of cutting force variation in face milling

The purpose of this paper is to present a developed cutting force model for multi-toothed cutting processes, including a complete set of parameters influencing the cutting force variation that has been shown to occur in face milling, and to analyse to what extent these parameters influence the total cutting force variation for a selected tool geometry. The scope is to model and analyse the cutting

High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer

Purpose: In this study, we investigated the prognostic impact of human RBM3 expression in colorectal cancer using tissue microarray-based immunohistochemical analysis. Experimental design: One polyclonal antibody and four monoclonal anti-RBM3 antibodies were generated and epitope mapped using two different methods. Bacterial display revealed five distinct epitopes for the polydonal antibody, while

A Bayesian Network for Probabilistic Reasoning and Imputation of Missing Risk Factors in Type 2 Diabetes

We propose a novel Bayesian network tool to model the probabilistic relations between a set of type 2 diabetes risk factors. The tool can be used for probabilistic reasoning and for imputation of missing values among risk factors. The Bayesian network is learnt from a joint training set of three European population studies. Tested on an independent patient set, the network is shown to be competiti

Time-Dependent Density-Functional Theory Meets Dynamical Mean-Field Theory: Real-Time Dynamics for the 3D Hubbard Model

We introduce a new class of exchange-correlation potentials for a static and time-dependent density-functional theory of strongly correlated systems in 3D. The potentials are obtained via dynamical mean-field theory and, for strong enough interactions, exhibit a discontinuity at half-filling density, a signature of the Mott transition. For time-dependent perturbations, the dynamics is described in

Lifestyle enterprising: the "ambiguity work" of Swedish horse-farmers

The article introduces the concept of ambiguity work as a specific form of work-life balancing performed when making a livelihood based on leisure interests and a personal lifestyle. The study focuses on female self-employed horse-farmers in Sweden involved in service work with and through horses. Through an analysis of narratives and practices of this service work, based on ethnographic interview

Analysis for Science, Engineering and Beyond : The Tribute Workshop in Honour of Gunnar Sparr held in Lund, May 8-9, 2008

This book project was initiated at The Tribute Workshop in Honour of Gunnar Sparr and the follow-up workshop Inequalities, Interpolation, Non-commutative Analysis, Non-commutative Geometry and Applications, held at the Centre for Mathematical Sciences, Lund University in May and November of 2008. The resulting book is dedicated in celebration of Gunnar Sparr's sixty-fifth anniversary and more th

International Centre for Settlement of Investment Disputes Tribunal, Spyridon Roussalis v Romania, Decision of 7 December 2011

Abstract in UndeterminedInternational lawyers interested in international investment law and treaty interpretation issues should consider the international award recently delivered by an ICSID Tribunal in the case of Spyridon Roussalis v Romania.1 The case arose out of the privatization of a Romanian warehouse company (SC Malimp SA). On 23 October 1998, another Romanian company (Continent SRL) ent

Environmental Influence on Language Acquisition: Comparing Second and Foreign Language Acquisition of Swedish

This article explores the influence of the learning environment on the second language acquisition of Swedish. Data were collected longitudinally over 1 year from 35 university students studying Swedish in Malmo, Sweden, and in Melbourne, Australia. Three areas were investigated: grammar, pragmatics, and lexicon. The development of grammar was analyzed within the framework of Processability Theory

Occurrence and fate of fatty acyl biomarkers in an ancient whale bone (Oligocene, El Cien Formation, Mexico)

The taphonomic and diagenetic processes by which organic substances are preserved in animal remains are not completely known and the originality of putative metazoan biomolecules in fossil samples is a matter of scientific discussion. Here we report on biomarker information preserved in a fossil whale bone from an Oligocene phosphatic limestone (El Cien Fm., Mexico), with a focus on fatty acyl com

Immediate responses in soil chemistry, vegetation and ground beetles to soil perturbation when implemented as a restoration measure in decalcified sandy grassland

The species-rich calcareous grassland communities in Europe are gradually disappearing due to lack of management such as grazing or cultivation, resulting in decalcification and reduction of gaps in the vegetation. In this study, experimental soil perturbation (deep and shallow) was performed in degenerated sandy grassland in plots with a size of 8 x 8 m, using a randomised block design. The hypot

Impact of prefiltration on membrane performance during isolation of hemicelluloses extracted from wheat bran

Hemicelluloses extracted from wheat bran have to be separated from impurities in order to obtain a valuable product at high concentration and purity. A previous investigation showed that separation by ultrafiltration is possible, but the flux was low due to the high viscosity of the solution and the presence of gel-forming substances in the solution. In this investigation the influence of prefiltr

Vorinostat in patients with advanced malignant pleural mesothelioma who have progressed on previous chemotherapy (VANTAGE-014): a phase 3, double-blind, randomised, placebo-controlled trial.

Vorinostat is a histone deacetylase inhibitor that changes gene expression and protein activity. On the basis of the clinical benefit reported in patients with malignant pleural mesothelioma treated in a phase 1 study of vorinostat, we designed this phase 3 trial to investigate whether vorinostat given as a second-line or third-line therapy improved patients' overall survival.

Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation.

Delamination plays a pivotal role during normal development and cancer. Previous work has demonstrated that delamination and epithelial cell movement within the plane of an epithelium are associated with a change in cellular phenotype. However, how this positional change is linked to differentiation remains unknown. Using the developing mouse pancreas as a model system, we show that β cell delamin

Comparative visual function in four piscivorous fishes inhabiting Chesapeake Bay

Maintaining optimal visual performance is a difficult task in photodynamic coastal and estuarine waters because of the unavoidable tradeoffs between luminous sensitivity and spatial and temporal resolution, yet the visual systems of coastal piscivores remain understudied despite differences in their ecomorphology and microhabitat use. We therefore used electroretinographic techniques to describe t