While once abstruse, 14-3-3 proteins are now well known as players in several cellular processes. These processes range from apoptosis and mitosis in mammals and yeast, to regulation of primary metabolism in plants. To date, 104 proteins have been shown to interact with 14-3-3s of which 85 are found in mammals and yeast, and 21 are found in plants. Their consensus action is to bind to phosphorylat

This paper presents the results of an explorative study on the strategies and tactics applied by the mechanical designer during the later phases of the design process. The method chosen for this study is experiment-based, which is appropriate for an in-depth examination of the designer's activities. Six experiments have been run based on three dimensions: 1) the carrying out of basic design tasks

Syftet med detta projekt var att studera samspelet mellan friktion, balansförmåga och halkrisker, samt att ta fram designrekommendationer för friktionskrav och halksäkrare skor och underlag. Sex studier har utförts innefattande friktionsmätningar av skor på olika underlag och temperaturer, studier av stående balans och gång på ramp med justerbar lutning samt fokusgruppintervjuer. Resultaten visar

Popular Abstract in Swedish Arkitekter har kritiserats för att ha en vag föreställning om begreppet kropp och hur det förhåller sig till den arkitektur de gestaltar. Om kropp alls medvetandegörs är det på ett allmänt och självidentifierande plan, alternativt genom de standardiserad mått som olika byggnormer föreskriver. Arkitekturens kroppsliga relationer och kroppens sensoriska meningsskapande ärBeginning with the notion that spatial and material qualities of architecture set limits and create conditions for how we make use of it, the overall aim and ambition of this thesis is to develop this notion and to contribute to a deeper understanding of the relationships that are produced between the materiality of architecture and a bodily appropriation of it. To investigate this the thesis esta

Abstract is not available

Det centrala i 2008-års sjukreform var att förmå människor att ta tillvara den arbetsförmåga de har kvar. Den tanken har funnits sedan 1990-talet. Reformens innehåll präglas av en koppling till en tankekedja där sjukdom förknippats med ett starkt skyddsvärde, högre statligt ersättningstak, obligatorisk deltagande i försäkringen och ett betydande skydd mot påtvingad omskolning till enklare arbetsup

The enzyme deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase, EC 3.6.1.23) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate. The reaction suppresses misincorporation of uracil into DNA and provides dUMP for the de novo synthesis of dTTP. dUTPase is a widespread enzyme and the fact that many viruses encode a dUTPase of their own suggests the enzyme to be important for the viral li

Popular Abstract in Swedish Kan vårdbehov mätas? Under de senaste decennierna har studier från olika delar av västvärlden kunnat visa att det finns skillnader mellan olika sociala klasser i sjukdomsförekomst och förtidig död. Sådana skillnader finns även i Sverige, trots att politikerna sedan länge satsat på utjämning av klasskillnader och vård på lika villkor för alla. Den ekonomiska tillväxten Aims: To analyse the associations between health and neighbourhood social position, measured by a composite index (Care Need Index, CNI). Furthermore evaluate CNI in preparation for future analysis of its usefulness for allocating primary health care resources to deprived neighbourhoods. Methods: One fourth of the Swedish general practitioners ranked the impact of eight different variables: elder

This paper presents a design study aiming to compare a PMSM, EMSM and an SMSM solution in order to rind the most competitive one for the BAS application. The study is mainly based on FE calculations, which are contrasted with the results obtained from a common car alternator. The highlights are efficiency and torque characteristics, and the way they contribute to improve the most important feature

The unison songs has united people about common goals and experiences in the three great folk movements in Sweden, the Revivalist movement, the Temperance movement and the Socialist movement, especially during the most expansive period, 1850-1920. The aim/purpose of my investigation has been to examine how the different ideolgies are breaking against each other in the songs published for unison so