Development and characterization of ex vivo inflammatory Mannan-Induced Psoriasis model using Ncf1 mutated mice in a 3D nanofiber cell culture system
Autoimmune diseases are complex and characterized by the loss of self-tolerance to self-antigens, leading to an immune attack on target tissues of the body. Psoriasis (Ps) and psoriasis arthritis (PsA) are poorly understood autoimmune diseases with unknown genetic and environmental sources. It has been previously demonstrated that a single intra peritoneal injection of mannan induces an acute infl