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Several studies have demonstrated a link between diabetes and the dysfunction of the inner ear. Few studies, however, have reported the signalling mechanisms involved in metabolic control in human inner ear cells. Knowledge of the expression and role of the insulin receptor and downstream signalling components in the inner ear is sparce. Our immunohistochemistry approach has shown that the insulin

Predator avoidance behaviour costs time, energy and opportunities, and prey animals need to balance these costs with the risk of predation. The necessary decisions to strike this balance are often based on information that is inherently imperfect and incomplete due to the limited sensory capabilities of prey animals. Our knowledge, however, about how prey animals solve the challenging task of rest

Frequency-modulated light field fluctuations due to moving particles in colloidal suspensions are examined using heterodyne interferometry. The power spectrum is the combined result of a time-of-flight-related frequency distribution due to light scattering and frequency shifts due to the Doppler effect. An approximation model is developed based on diffusion theory and verified experimentally. The

This article deals with the reception of German film star Kristina Söderbaum in her native Sweden. Söderbaum reached the heights of superstardom, becoming one of Germany’s top box office stars of all time. Until 1945 she appeared exclusively in films directed by her husband, Veit Harlan. The Swedish press closely monitored Söderbaum’s career, though her most infamous film Jud Süss/Jew Süss (1940)

NINDS (National Institute of Neurological Disorders and Stroke)-SiGN (Stroke Genetics Network) is an international consortium of ischemic stroke studies that aims to generate high-quality phenotype data to identify the genetic basis of pathogenic stroke subtypes. This analysis characterizes the etiopathogenetic basis of ischemic stroke and reliability of stroke classification in the consortium.

A search for direct pair production of supersymmetric top squarks ((t) over tilde (1)) is presented, assuming the (t) over tilde (1) decays into a top quark and the lightest supersymmetric particle, (chi) over tilde (0)(1), and that both top quarks decay to purely hadronic final states. A total of 16 (4) events are observed compared to a predicted standard model background of 13.5(-3.6)(+3.7) (4.4

We present an improved numerical scheme for numerical simulations of low Mach number turbulent reacting flows with detailed chemistry and transport. The method is based on a semi-implicit operator-splitting scheme with a stiff solver for integration of the chemical kinetic rates, developed by Knio et al. [O.M. Knio, H.N. Najm, P.S. Wyckoff, A semi-implicit numerical scheme for reacting flow II. St

A hypothesis about (transient) colloidal stability as a controlling mechanism for particle formation in SBA-15 is presented. The hypothesis is based on results from both in situ and ex situ investigations, including cryogenic transmission electron microscopy (cryo-TEM), UV-vis spectroscopy, and dynamic light scattering (DLS). Cryo-TEM images show that particles grow via the formation of silica-Plu

Arterial stiffness is influenced by advancing age and vascular disease and is an independent risk factor for cardiovascular events and death. Using ultrasound measurements, arterial stiffness in a specific arterial segment can be assessed. The aim of this observational study was to explore the prospective and cross-sectional associations between arterial stiffness measured by ultrasound locally in

The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to dielectron or dimuon final states. Results are presented from an analysis of proton-proton (pp) collisions at a center-of-mass energy of 8 TeV corresponding to an integrated luminosity of 20.3 fb(-1) in the dimuon channel. A narrow resonance with Standard Model Z couplings to fermions is excluded

Pancreatic cancer is commonly detected at advanced stages when the tumor is no longer amenable to surgical resection. Therefore, finding biomarkers for early stage disease is urgent. Here, we show that high-definition mass spectrometry (HDMS(E)) can be used to identify serum protein alterations associated with early stage pancreatic cancer.

Background. Globally, general practitioners (GPs) write more than 90% of all antibiotic prescriptions. This study examines the experiences of Lithuanian and Russian GPs in antibiotic prescription for upper respiratory tract infections, including their perceptions of when it is not indicated clinically or pharmacologically. Methods. 22 Lithuanian and 29 Russian GPs participated in five focus group

AimTo present the protocol of a two-group quasi-experimental study of spouses' involvement through case management (The SICAM-trial) in older patients' fast-track programmes during total hip replacement. BackgroundPatients in fast-track programmes are required to take an active part in their treatment and rehabilitation. Spouses of older patients can often provide valued practical and emotional su

The aim of present study is to inverstigate the association between antibody levels after vaccination with 7-valent pneumococcal conjugate vaccine (PCV7) and subsequent serious pneumococcal infections in rheumatoid arthritis (RA) and spondylarthropathy (SpA) patients.

BACKGROUND: Enterocytes are exposed to antigens present in the intestinal lumen, like beta-glucans that are carbohydrate structures present not only in the cell wall of yeast and fungi but also in cereals. Beta-glucans are known for their immune modulating properties and we have earlier reported an increased immune response by enterocytes after addition of fecal water prepared from ileostomic cont

Consideration of urban microclimate and thermal comfort is an absolute neccessity in urban development, and a set of guidelines for every type of climate must be elaborated. However, to develop guidelines, thermal comfort ranges need to be defined. The aim of this study was to evaluate the behaviour of different thermal indices by investigating different thermal environments in Damascus during sum

The strongly temperature-dependent ionic mobility in polymer electrolytes is used to freeze in specific ionic charge environments around a nanowire using a local wrap-gate geometry. This makes it possible to set both the threshold voltage for a conventional doped substrate gate and the local disorder potential at temperatures below 220 K. These are characterized in detail by combining conductance

A palynological investigation has been conducted on Lower-Upper Miocene sediments from Jylland, Denmark, corresponding to the time interval of about 19 to 8 Ma. The sediments, derived from the Sdr. Vium drill core, were deposited in marine to marginal-marine environments, as shown by the relatively high abundance of dinoflagellate cysts in all samples. Nevertheless, rich and diverse pollen assembl

Landowners' choice of management practices will directly affect the conservation of biodiversity in large-scale productive landscapes such as forests and agricultural areas. Using the value-belief-norm theory, this study identifies the extent to which landowners differ regarding the psychological variables antecedent of a moral obligation to protect local biodiversity after participation in conser