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Omnipotence and Other Possibilities

The notion of omnipotence has proved to be quite recalcitrant to analysis. Still, during the last three decades or so, there has resurfaced a clever argument to the effect that, whatever omnipotence is, it cannot be exemplified in God: an allegedly impeccable and all-perfect being. Scrutinizing this argument, however, I find it less than convincing. Moreover, and more importantly, I venture a posi

Next generation DNA sequencing of a Swedish Malignant Hyperthermia cohort.

Malignant Hyperthermia (MH) related mutations have been identified in the ryanodine receptor type 1 gene (RYR1) and in the dihydropyridine gene (CACNA1S), but about half of the patients do not have causative mutations in these genes. We wanted to study the contribution of other muscle genes to the RYR1 phenotypes.

Challenges in Flexible Safety-Critical Software Development -- An Industrial Qualitative Survey

Context. Development of safety-critical systems is mostly governed by process-heavy paradigms, while increasing demands on flexibility and agility also reach this domain. Objectives. We wanted to explore in more detail the industrial needs and challenges when facing this trend. Method. We launched a qualitative survey, interviewing engineers from four companies in four different industry domains.

Thermally induced phase transitions of barium oxalates

The thermal decomposition of BaC2O4 center dot 3.5H(2)O and BaC2O4 center dot 0.5H(2)O was investigated using in situ synchrotron X-ray and neutron powder diffraction. The decomposition routes for the barium oxalate hydrates were observed to depend on the applied heating rate. Thermal decomposition of BaC2O4 center dot 0.5H(2)O showed transformation to alpha-BaC2O4 and to beta-BaC2O4 prior to the

A Novel Application of Plasmonics: Plasmon-Driven Surface-Catalyzed Reactions

The first experimental and theoretical evidence of the surface-catalyzed reaction of p,p'-dimercaptoazobenzene (DMAB) produced from para-aminothiophenol (PATP) by local surface plasmons was reported in 2010, and since that time a series of investigations have supported these findings using different experimental and theoretical methods. Recent work has also found that local plasmons can drive a su

Assessment of time patterns of activity and rest in full-shift recordings of trapezius muscle activity - Effects of the data processing procedure

The purpose of this paper was to compare the effects of different data reduction procedures on the values of variables characterizing the time pattern of trapezius muscle activity during full work shifts. Surface electromyography (EMG) of the right and left upper trapezius muscles were obtained from 40 young subjects in different occupations, mainly electricians, hairdressers and students. The tar

Differences in physical activity patterns in patients with spondyloarthritis.

OBJECTIVE: To study patient reported physical activity in patients with spondyloarthritis (SpA) and possible differences in physical activity patterns between the SpA subtypes and genders. METHODS: In 2009 a questionnaire including questions concerning physical activity was sent to patients with a SpA diagnosis (n=3711). The WHO "Global recommendations of physical activity for health" requirin

Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome

BACKGROUND Individual corrected QT interval (QTc) may vary widely among carriers of the same long QT syndrome (LOTS) mutation. Currently, neither the mechanism nor the implications of this variable penetrance are well understood. OBJECTIVES To hypothesize that the assessment of QTc variance in patients with congenital LOTS who carry the same mutation provides incremental prognostic information on

Accuracy and reproducibility of a novel dynamic volume flow measurement method.

In clinical practice, blood volume flow (BVF) is typically calculated assuming a perfect parabolic and axisymmetric velocity distribution. This simple approach cannot account for the complex flow configurations that are produced by vessel curvatures, pulsatility and diameter changes and, therefore, results in a poor estimation. Application of the Womersley model allows compensation for the flow di

The new work ethics of consumption and the paradox of mundane brand resistance

In terms of consumer resistance and marketplace ideologies, consumer researchers have called for a more nuanced conceptualization of consumption moralism in order to avoid the simplistic trope of inside/outside the marketplace (e.g. Arnould, 2007; Luedicke et al., 2010; Penaloza and Price, 1993; Thompson, 2004). With the aim of contributing to this quest, this article brings together two originall

Risk of hepatocellular carcinoma and cancers at other sites among patients diagnosed with chronic hepatitis B virus infection in Sweden.

Hepatitis B virus (HBV) infection is one of most common viral infections worldwide. While chronic HBV infection has been shown consistently to be associated with hepatocellular carcinoma, data on associations with cancers at other sites are limited. In this study a total of 10,197 patients were diagnosed with chronic HBV infection in Sweden, and they were retrieved from the nationwide Swedish Hosp

Product variety and the demographic transition

Why does the rate of population growth decline in the face of economic growth? We show that growing product variety may induce a permanent reduction in the demand for children and a continuous rise in income and consumption. (C) 2009 Elsevier B.V. All rights reserved.

One man, 73 years, and 25 species. Evaluating phenological responses using a lifelong study of first flowering dates.

Phenological shifts linked to global warming reflect the ability of organisms to track changing climatic conditions. However, different organisms track global warming differently and there is an increasing interest in the link between phenological traits and plant abundance and distribution. Long-term data sets are often used to estimate phenological traits to climate change, but so far little has

Low variability and absence of phenotypic correlates of Clock gene variation in a great tit Parus major population

Studies of a range of taxa, including birds, have revealed latitudinal clines in allele length at the conserved Clock locus, a gene with known influences on behaviour and physiology. Such clines might reflect adaptation to seasonal variation, a suggestion supported by a recent within-population analysis of blue tits Cyanistes caeruleus, which found associations between Clock genotype and timing of

Scaling up requirements engineering - exploring the challenges of increasing size and complexity in market-driven software development

[Context & motivation] Growing software companies with increasing product complexity face the issue of how to scale up their Requirements Engineering (RE) practices. In market-driven requirements engineering, release planning and scoping decisions are increasingly challenging as the size and complexity increases. [Problem] This paper presents initial results of an on-going exploratory, qualita

Topological crystalline insulator states in Pb1-xSnxSe

Topological insulators are a class of quantum materials in which time-reversal symmetry, relativistic effects and an inverted band structure result in the occurrence of electronic metallic states on the surfaces of insulating bulk crystals. These helical states exhibit a Dirac-like energy dispersion across the bulk bandgap, and they are topologically protected. Recent theoretical results have sugg

Are children with stronger cognitive capacity more or less disturbed by classroom noise and dysphonic teachers?

Purpose: This study aimed to explore if dysphonic voice quality affects children's performance on a language comprehension test, the Test for Reception of Grammar-2 (TROG-2), performed in simultaneous background noise (non-semantic babble). A further aim was to investigate the role of Working Memory Capacity (WMC) and Executive Functioning (EF) in coping with the voice against a background of babb

Functional consequences of sequence variation in the pheromone biosynthetic gene pgFAR for Ostrinia moths

Pheromones are central to the mating systems of a wide range of organisms, and reproductive isolation between closely related species is often achieved by subtle differences in pheromone composition. In insects and moths in particular, the use of structurally similar components in different blend ratios is usually sufficient to impede gene flow between taxa. To date, the genetic changes associated