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Estimating the Causal Impact of Macroeconomic Conditions on Income-Related Mortality

To-date the macroeconomic conditions-mortality literature on income-related inequality in mortality has relied on subgroup analysis, mainly using income as a stratification variable, but this nearly always causes selection bias yielding results that are hard to interpret. To solve this bad control problem, we apply a novel technique based on recentered influence function regression of overall inco

Effectiveness of the European Natura 2000 network to sustain a specialist wintering waterbird population in the face of climate change

Analysis of coordinated Greater Scaup (Aythya marila) count data from the last 30 years showed a 38.1% decrease in wintering numbers in North-West Europe, from 309,000 during 1988–1991 to c.192,300 individuals during 2015–2018. Annual trends in wintering numbers differed throughout the range. Numbers decreased in the UK, Ireland, and in the Netherlands, while numbers were stable in Denmark. German

Field-Scale Quality Control of Lime-Cement Pillar in Conductive Clay Using Electrical Resistivity Tomography

Ground improvement with lime-cement pillars is becoming increasingly common in the Nordic countries for exploitation of areas with poor stability. However, there is no non-destructive method for quality control of the ground improvement. Significant changes in the electrical properties after mixing of the binders make electrical resistivity tomography (ERT) a potential method. In connection with l

Temporal hierarchies with autocorrelation for load forecasting

We propose three different estimators that take into account the autocorrelation structure when reconciling forecasts in a temporal hierarchy. Combining forecasts from multiple temporal aggregation levels exploits information differences and mitigates model uncertainty, while reconciliation ensures a unified prediction that supports aligned decisions at different horizons. In previous studies, wei

Unveiling the process of sustainable renovation

Thuvander, L, Femenias, P, Mjörnell, K, Meiling, P, Unveiling the process of sustainable renovation. Published in open access journal Sustainability 2012, 4(6), in May 2012.Renovation processes are complex and there is a risk of underestimating architectural, cultural, and social values in favor of exterior and interior upgrading, energy efficiency and financing. A synthesized, systematic process is needed for making decisions about renovation measures. The aim of this paper is to survey decision-making procedures aimed for sustainable renovation. We inventory existi

Multi-objective performance assessment of wastewater treatment plants combining plant-wide process models and life cycle assessment

Multi-objective performance assessment of operational strategies at wastewater treatment plants (WWTPs) is a challenging task. The holistic perspective applied to evaluation of modern WWTPs, including not only effluent quality but also resource efficiency and recovery, global environmental impact and operational cost calls for assessment methods including both on- and off-site effects. In this stu

Altered structural network organization in cognitively normal individuals with amyloid pathology

Recent findings show that structural network topology is disrupted in Alzheimer's disease (AD), with changes occurring already at the prodromal disease stages. Amyloid accumulation, a hallmark of AD, begins several decades before symptom onset, and its effects on brain connectivity at the earliest disease stages are not fully known. We studied global and local network changes in a large cohort of

Implementation of the Trade Secrets Directive into National Law: Portugal and Spain

The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple

Automation of building permission by integration of BIM and geospatial data

The building permission process is to a large extent an analogue process where much information is handled in paper format or as pdf files. With the ongoing digitalisation in society, there is a potential to automate this process by integrating Building Information Models (BIM) of planned buildings and geospatial data to check if a building conforms to the building permission regulations. In this

Re-evaluation of HER2 status in 606 breast cancers—gene protein assay on tissue microarrays versus routine pathological assessment

Human epidermal growth factor receptor 2 (HER2) status in breast cancer is routinely determined through immunohistochemistry (IHC) and/or in situ hybridisation (ISH) performed on whole tissue sections (WS). The purpose was to evaluate whether a gene protein assay (GPA) combining IHC with ISH, performed on breast cancer tissue microarray (TMA), is suitable for large-scale retrospective HER2 status

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Det er kjent fra før at langdistansebinding av refleksive pronomen forekommeri norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevdaat langdistanse binding er mulig i visse ikke-logoforiske kontekster. I denne artikkelenargumenterer jeg for at langdistansebinding i norsk alltid er logoforisk,og at det samme gjelder for mellomdistansebinding. Det er bare lokal bindingsom Det er kjent fra før at langdistansebinding av refleksive pronomen forekommer i norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevda at langdistanse­binding er mulig i visse ikke-logoforiske kontekster. I denne artikkelen argumenterer jeg for at langdistansebinding i norsk alltid er logoforisk, og at det samme gjelder for mellomdistansebinding. Det er bare lokal binding

Less-well known functions of cyclin/CDK complexes

Cyclin-dependent kinases (CDKs) are activated by cyclins, which play important roles in dictating the actions of CDK/cyclin complexes. Cyclin binding influences the substrate specificity of these complexes in addition to their susceptibility to inhibition or degradation. CDK/cyclin complexes are best known to promote cell cycle progression in the mitotic cell cycle but are also crucial for importa