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In order to meet the EU's climate and resource efficiency targets, changes in our daily-life behaviours, as well as business models, are urgently necessary. More insights are needed to make real changes based on research with a systems perspective. We developed a system dynamics model to analyse the environmental benefits of a transition from ownership-based to access-based household laundry activ

Previous research highlights the impact of care and treatment in ICUs on the patient recovery process and wellbeing. However, little is known about how the interior design in the ICU settings may affect patients' wellbeing. Objective: The aim of this study is, by using a lifeworld perspective, to reveal the meanings of the ICU settings as a place of care. Design: Nine patients from three ICUs in S

The sympathetic nervous system and the adrenergic receptors play an important role in regulation of blood pressure. This study explored the associations between functional polymorphisms of the α 2B -, β 1 -, and β 2 -adrenergic receptor genes and obstructive sleep apnea (OSA) in hypertensive patients and hypertension in patients with OSA in a populationbased sample of 157 hypertensive patients and

BACKGROUND: Individuals with mental health problems often need support from vocational rehabilitation professionals in their return-To-work (RTW) process. Research has shown that this support can be deficient, with vocational rehabilitation professionals lacking relevant knowledge and an underlying belief in the individual's ability to resume a working life. More understanding is therefore needed

This article focuses on the negotiated distinction between commercial and non-commercial spheres of life through the phenomenon of lifestyle entrepreneurship. Lifestyle entrepreneurship is a concept used for a form of self-employment, based on the business owner´s own hobby or lifestyle. The article is based on a study of lifestyle enterprising in the tourism and hospitality industries in southern

There is a great need for targeted protein assays with the capacity of sensitive measurements in complex samples such as plasma or serum, not the least for clinical purposes. Proteomics keeps generating hundreds of biomarker candidates that need to be transferred towards true clinical application through targeted verification studies and towards clinically applicable analysis formats. The immunoaf

The effective use of modern control theory requires suitable mathematical models of the objects to be controlled and of the disturbances. Paper machines have been controlled digitally for a long time. Digital control of basis weight and moisture content is in fact one of the few examples where a digital computer and sensors form a standard package. In spite of this there are still significant gaps

Diabetes is a bihormonal disorder resulting from combined insulin and glucagon secretion defects. Mice lacking fumarase (Fh1) in their β cells (Fh1βKO mice) develop progressive hyperglycemia and dysregulated glucagon secretion similar to that seen in diabetic patients (too much at high glucose and too little at low glucose). The glucagon secretion defects are corrected by low concentrations of tol

The sustainable development of cities is threatened by a worldwide water crisis. Improved social learning is urgently needed to transform urban water governance and make it more integrated and adaptive. However, empirical studies remain few and fragmented. Therefore, the aim of this paper is to analyse how social learning has supported or inhibited sustainable transformations in urban water govern

In recent decades, there has been a global recognition of the co-constitutive relationship between gender justice and peaceful transformation of previously war-torn societies. This chapter investigates how “women-friendly states” have located their foreign policies within notions of gender equality and empowerment. It focuses on how feminist foreign policy is to all intents and purposes ethical an

Background: Essential proteins play an important role in the process of life, which can be identified by experimental methods and computational approaches. Experimental approaches to identify essential proteins are of high accuracy but with the limitation of time and resource-consuming. Objective: Herein, we present a computational model (PEPRF) to identify essential proteins based on machine lear

Background: Young people's daily lives and social interactions changed remarkably during the COVID-19 pandemic as schools and cinemas closed, leisure activities were cancelled, and gatherings were regulated. Questions have been raised by the media, schools, policy makers, and research communities about the effect on young people's online behaviors. Objective: This cross-sectional study aimed to st

We present the archaeological discovery and microscale X-ray Computed Tomography (µCT) scanning of a silver coin purse lost in a medieval shipwreck while the king who issued many of the coins was aboard. The find demonstrates that shipwrecks are extraordinary repositories of historical information, in this case providing insight into one of the most important and dramatic events of medieval Scandi

Resting heart rate is a determinant of cardiac output and physiological homeostasis. Although a simple, but critical, parameter, this vital sign predicts adverse outcomes, including mortality, and development of diseases in otherwise normal and healthy individuals. Temporal changes in heart rate can have valuable predictive capabilities. Heart rate can reflect disease severity in patients with var

Complement C3 was originally regarded as a serum effector protein, although recent data has emerged suggesting that intracellular C3 can also regulate basic cellular processes. Despite the growing interest in intracellular C3 functions, the mechanism behind its generation has not been demonstrated. In this study we show that C3 can be expressed from an alternative translational start site, resulti