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Indoor to outdoor ratio of particle chemical components in an occupied residence

IntroductionConsidering that on average in developed countries we spend about 65% of our time in private homes, understanding the exposures in homes is of outmost importance. Aerosol concentrations indoors come from indoor sources, infiltrate from outdoors and can be formed from precursors both of indoor and outdoor origin. Several characteristics and processes influence the properties of aerosols

Epidemiology and Pathogenesis of Type 1 Diabetes

Type 1 diabetes is an autoimmune disease that affects 0.1 to nearly 1% of the population, dependent on the country, with its highest incidence around 10–15 years of age. The incidence has increased over time, approximately doubling over the past 2–3 decades. The incidence varies across the world, with the highest among populations of (Northern) European origin and the lowest in Japan. Most diabeti

The breakup of the L-chondrite parent body 466 Ma and its terrestrial effects-a search for a mid-Ordovician biodiversity event

About a third of all meteorites that fall on Earth today, the stony L-chondrites, originate from a major breakup event in the asteroid belt 466 Ma, in the early Darriwilian. This is the largest asteroid breakup in the past three billion years documented by K-Ar gas-retention ages of recently fallen meteorites. There has been a debate whether the breakup had any effects on Earth’s biota. Based main

Dealing with police stops : How young people with ethnic minority backgrounds narrate their ways of managing over-policing in the Nordic countries

Research shows that young people within ethnic minorities are subjected to police control more often than others, which seems to have a damaging effect on their trust in the police as well as on their wider sense of belonging. What is less often researched is how these young people deal with being over-policed. This article explores narratives of over-policing from those targeted by the police in Research shows that young people within ethnic minorities are subjected to police control more often than others, which seems to have a damaging effect on their trust in the police as well as on their wider sense of belonging. What is less often researched is how these young people deal with being over-policed. This article explores narratives of over-policing from those targeted by the police in

Digital Nomads’ Experiences on the Support of Digital Technologies in Relation to Social Isolation

The paper presents digital nomads’ experiences about the support of digital technologies in relation to social isolation. Despite the abundant access to digital technologies for organizational cooperative purposes, the challenge of social isolation constitutes one of the central concerns in nomadicity practices, affecting employees’ choice of working arrangements. To gain further knowledge on the

Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine

The kidneys operate at the interface of plasma and urine by clearing molecular waste products while retaining valuable solutes. Genetic studies of paired plasma and urine metabolomes may identify underlying processes. We conducted genome-wide studies of 1,916 plasma and urine metabolites and detected 1,299 significant associations. Associations with 40% of implicated metabolites would have been mi

Online Media Creation and L2 Motivation : A Socially Situated Perspective

Digital technologies are increasingly common in language learning. Online media creation provides scope for agency and spaces for identity construction, but empirically grounded conceptualizations of the influences on learners' motivation are lacking and the digital technology–second language motivation interface remains largely unexplored. Using a grounded theory ethnographic approach (Charmaz,20

The Impact of Out-of-School Factors on Motivation to Learn English : Self-discrepancies, Beliefs, and Experiences of Self-authenticity

English is today learnt in multitudes of settings worldwide, making it difficult to characterize relationships between motivation and context in generalized terms (Ushioda 2013). In settings where students have extensive encounters with English outside school, a reluctance to invest effort in formal learning has been observed. To investigate ways in which out-of-school encounters impact on motivat

The Ideal Multilingual Self : Validity, Influences on Motivation, and Role in a Multilingual Education

L2 motivation research has a longstanding monolingual bias. Recently, however, the motivational systems of a multilingual’s different languages have been conceptualized as constituting a multilingual motivational system, and it has been suggested that interactions between the ideal Lx self and the ideal Ly self can lead to the emergence of an ideal multilingual self. While the notion of an ideal m

Extracellular Vesicle-Associated TWEAK Contributes to Vascular Inflammation and Remodeling During Acute Cellular Rejection

Acute cellular rejection (ACR) is a leading cause of graft loss and death after heart transplantation despite effective immunosuppressive therapies. The identification of factors that impair graft vascular barrier function or promote immune cell recruitment during ACR could provide new therapeutic opportunities for the treatment of patients who receive transplants. In 2 ACR cohorts, we found the e

Genetically proxied impaired GIPR signaling and risk of 6 cancers

Preclinical and genetic studies suggest that impaired glucose-dependent insulinotropic polypeptide receptor (GIPR) signaling worsens glycemic control. The relationship between GIPR signaling and the risk of cancers influenced by impaired glucose homeostasis is unclear. We examined the association of a variant in GIPR, rs1800437 (E354Q), shown to impair long-term GIPR signaling and lower circulatin

Learned fear to social out-group members are determined by ethnicity and prior exposure

Humans, like other animals, have a tendency to preferentially learn and retain some associations more readily than others. In humans, preferential learning was originally demonstrated for certain evolutionary prepared stimuli, such as snakes and angry faces and later extended to human social out-groups based on race (Olsson et al., 2005). To address the generality of this social learning bias, we

Influences of bus traffic loading on asphalt concrete rutting

Permanent deformation is the primary failure mode for the asphalt concrete (AC) pavement in urban environment. It is mainly caused by a combination of heavy traffic load, low vehicle speed and channelised traffic. A rut prediction model would therefore be a valuable tool for planning maintenance scheduling and selecting an appropriate asphalt material. This study uses the PEDRO (Permanent deformat

Other syndromes of orthostatic intolerance : Delayed orthostatic hypotension, postprandial hypotension, postural orthostatic tachycardia syndrome, and reflex syncope

Apart from classical orthostatic hypotension, the gravitational force may strongly contribute to other forms of orthostatic intolerance, delayed and postprandial OH, postural orthostatic tachycardia syndrome (POTS), and reflex syncope. In delayed OH, the significant blood pressure drop occurs first after 3-min period of orthostasis, whereas in postprandial OH, the symptoms appear first approximate

“Programming is Not That Hard!”. When a Science Center Visit Increases Young Women’s Programming Ability Beliefs

To increase engagement with science and technology, young people around the world are encouraged to attend activities at science centers. But how effective are these activities? Since women have weaker ability beliefs and interest in technology than men, it is especially important to learn how science center visits affect them. In this study, we tested if programming exercises offered to middle sc

Universities under Neoliberalism : Ideologies, Discourses and Management Practices

The COVID-19 pandemic, the surge of populism, the climate crisis and many other destabilizing factors in our time, all point at the expectation of trustworthy knowledge and reliable organization devoted to knowledge production and dissemination. However, universities remain enmeshed in economic liberalization and ensuing cultural struggles where their funding, governance and practices reflect mark