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Det er kjent fra før at langdistansebinding av refleksive pronomen forekommeri norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevdaat langdistanse binding er mulig i visse ikke-logoforiske kontekster. I denne artikkelenargumenterer jeg for at langdistansebinding i norsk alltid er logoforisk,og at det samme gjelder for mellomdistansebinding. Det er bare lokal bindingsom Det er kjent fra før at langdistansebinding av refleksive pronomen forekommer i norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevda at langdistanse­binding er mulig i visse ikke-logoforiske kontekster. I denne artikkelen argumenterer jeg for at langdistansebinding i norsk alltid er logoforisk, og at det samme gjelder for mellomdistansebinding. Det er bare lokal binding

Less-well known functions of cyclin/CDK complexes

Cyclin-dependent kinases (CDKs) are activated by cyclins, which play important roles in dictating the actions of CDK/cyclin complexes. Cyclin binding influences the substrate specificity of these complexes in addition to their susceptibility to inhibition or degradation. CDK/cyclin complexes are best known to promote cell cycle progression in the mitotic cell cycle but are also crucial for importa

Internationally adopted children with and without a cleft lip and palate showed no differences in language ability at school-age

Aim: The aim of this study was to investigate language ability in internationally adopted children aged 7-8 years with and without a unilateral cleft lip and palate. Methods: We compared 27 internationally adopted children with a unilateral cleft lip and palate, adopted from China, with a group of 29 children without a cleft lip and palate, adopted from different countries. Participants were recru

Likelihood of admission to hospital from the emergency department is not universally associated with hospital bed occupancy at the time of admission

Background: The decision to admit into the hospital from the emergency department (ED) is considered to be important and challenging. The aim was to assess whether previously published results suggesting an association between hospital bed occupancy and likelihood of hospital admission from the ED can be reproduced in a different study population. Methods: A retrospective cohort study of attendanc

Cancer and Risk of COVID-19 Through a General Community Survey

Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 partic

A novel function for CDK2 activity at meiotic crossover sites

Genetic diversity in offspring is induced by meiotic recombination, which is initiated between homologs at >200 sites originating from meiotic double-strand breaks (DSBs). Of this initial pool, only 1-2 DSBs per homolog pair will be designated to form meiotic crossovers (COs), where reciprocal genetic exchange occurs between parental chromosomes. Cyclin-dependent kinase 2 (CDK2) is known to locali

Attributional change and common-sense knowledge

The paper reports a study of change in causal explanations in therapeutic conversations. It shows how attribution of thoughts, feelings and behaviours which are experienced as problematic, e.g. embarrassing, awkward, absurd or painful, is changed from internal to more external. Namely, analysis focuses on how dispositional attribution – attributing problematic thoughts, feelings and behaviours to

The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis

Progression through mitosis is balanced by the timely regulation of phosphorylation and dephosphorylation events ensuring the correct segregation of chromosomes before cytokinesis. This balance is regulated by the opposing actions of CDK1 and PP2A, as well as the Greatwall kinase/MASTL. MASTL is commonly overexpressed in cancer, which makes it a potential therapeutic anticancer target. Loss of Mas

Urban Water Governance and Learning—Time for More Systemic Approaches?

Social learning, especially triple-loop social learning involving institutional and governance changes, has great potential to address urban water issues such as flooding, drought, and pollution. It facilitates urban transition and the adoption of more systemic approaches and innovations. Social learning in water governance is a growing field, but the triple-loop learning concept remains vague and

Ten Years Of Sustainable Construction Aspects From A North And A South Perspective – A Review From Sustainable Building Conferences 1998-2007.

This paper is about, from a North and South different perspective, how the international focus of sustainable construction issues has changed over the past ten years. It is a review from four different international and regional sustainable building conferences between 1998 and 2007. The paper is mostly based of the first author's notes from the conferences, especially from the plenary sessions an

Striking the balance between formality and informality in safety-critical communication: Train traffic control calls

Talk in safety-critical activities displays features that distinguish it from both ordinary conversations as well as from other institutional talk, but it also shares some features with these. Formality and informality are both interactionally accomplished phenomena, although shaped through different sources. Safety rules and pre-printed forms constitute two sources of formalization, dictating how

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover

Ca2+-sensor proteins are generally implicated in insulin release through SNARE interactions. Here, secretagogin, whose expression in human pancreatic islets correlates with their insulin content and the incidence of type 2 diabetes, is shown to orchestrate an unexpectedly distinct mechanism. Single-cell RNA-seq reveals retained expression of the TRP family members in β-cells from diabetic donors.