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Monitoring a microservice system may bring a lot of benefits to development teams such as early detection of run-time errors and various performance anomalies. In this study, we explore deep learning (DL) solutions for detection of anomalous system's behavior based on collected monitoring data that consists of applications' and systems' performance metrics. The study is conducted in a collaboratio

This chapter provides conceptual and empirical foundations for smart specialization, a policy approach of far-reaching importance in the European context. We interpret the very notion as “diversified” specialization into areas of existing or potential competitive advantage, which differentiates a region/nation from others. “Smart” relates to the identification of these areas through a process of e

Globally, the lifespan of populations increases but the healthspan is lagging behind. Previous research showed that survival into extreme ages (longevity) clusters in families as illustrated by the increasing lifespan of study participants with each additional long-lived family member. Here we investigate whether the healthspan in such families follows a similar quantitative pattern using three-ge

Space Syntax theory is a methodological framework for describing and analysing the relationships between spaces and buildings. The fundamental building blocks of Space Syntax are called axial lines, which represent lines of sight from a specific point in space. These lines can then be used to quantitatively analyse the integration (or attractiveness) of an area. However, many public squares and tr

Prostate apoptosis response-4 (Par-4) is a tumor suppressor that induces apoptosis in cancer cells. However, the physiological function of Par-4 remains unknown. Here we show that conventional Par-4 knockout (Par-4-/-) mice and adipocyte-specific Par-4 knockout (AKO) mice, but not hepatocyte-specific Par-4 knockout mice, are obese with standard chow diet. Par-4-/- and AKO mice exhibit increased ab

Leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins have been implicated as regulators of growth factor signaling; however, the possible redundancy among mammalian LRIG1, LRIG2, and LRIG3 has hindered detailed elucidation of their physiological functions. Here, we show that Lrig-null mouse embryonic fibroblasts (MEFs) are deficient in adipogenesis and bone morphogenetic protein (B

Women tend to have lower interest in engineering as compared to men, which previous research has shown is partly explained by gender differences in self-efficacy, social belongingness and communal career goals. Therefore, to attract more women to engineering, effective interventions are needed that target these factors. In this study, we evaluated an industry-designed intervention for high school

Type 1 diabetes (T1D) is an autoimmune disease that results in the destruction of insulin producing pancreatic β-cells. One of the genes associated with T1D is TYK2, which encodes a Janus kinase with critical roles in type-Ι interferon (IFN-Ι) mediated intracellular signalling. To study the role of TYK2 in β-cell development and response to IFNα, we generated TYK2 knockout human iPSCs and directed

Most cross-cultural studies on management control have compared Anglo-Saxon firms to Asian firms, leaving us with limited understanding of potential variations between developed Western societies. This study addresses differences and similarities in a wide variety of management control practices in Anglo-Saxon (Australia, English Canada), Germanic (Austria, non-Walloon Belgium, Germany) and Nordic

Objectives. The aim of this systematic review was to describe interventions which promote safe patient handling and movement (PHM) among workers in healthcare by reviewing the literature on their effectiveness for work and health-related outcomes. Methods. Databases were searched for studies published during 1997–2018. Measures were operationalized broadly, capturing outcomes of work and health. O

Backgroundamong the 1–1.5 billion persons with hypertension globally only, 20–30% have controlled blood pressure (BP). The most important problem identified is non-adherence to treatment, i.e., failure to change lifestyle and to take prescribed medication. Knowledge about the reasons for this is limited.ObjectivesThe aim of the study was to explore people's experiences of having hypertension.Desig

The presentation and underlying pathophysiology of type 2 diabetes (T2D) is complex and heterogeneous. Recent studies attempted to stratify T2D into distinct subgroups using data-driven approaches, but their clinical utility may be limited if categorical representations of complex phenotypes are suboptimal. We apply a soft-clustering (archetype) method to characterize newly diagnosed T2D based on

Due to the increasing share of older people worldwide, the United Nations has directed an initiative towards a "decade of healthy ageing" to promote "age-friendly environments". This study aims to gain a deeper understanding of how to promote social participation and everyday mobility in later life. The ambition is to increase the knowledge about how to create more age-friendly environments and soDue to the increasing share of older people worldwide, the United Nations has directed an initiative towards a "decade of healthy ageing" to promote "age-friendly environments". This study aims to gain a deeper understanding of how to promote social participation and everyday mobility in later life. The ambition is to increase the knowledge about how to create more age-friendly environments and so

Det globala akademiska landskapet har förändrats avsevärt sedan 1990-talet. Idag deltar fler länder än någonsin i produktionen av forskning av hög kvalitet, och internationella samarbeten inom högre utbildning har ökat markant under de senaste tre årtiondena på grund av globalisering och ökad personmobilitet. Det är tydligt att internationella utbyten och ökad personmobilitet har stärkt Sveriges fThe global academic landscape has changed significantly since the 1990s. Today, more countries than ever participate in the production of high-quality research, and international collaborations in higher education have increased dramatically over the past three decades due to globalization and increased personal mobility. It is clear that international exchanges and increased personal mobility hav

Accelerated deterioration of the constituting materials is important for the long-term performance of bridges or any other load-bearing structure with several-decades-long service life. In addition to the economic consequences due to increased maintenance and repair needs, severe deterioration can lead to catastrophic collapses with possible injuries, life losses, and impairments to infrastructure

Over the years, Carbon Capture and Sequestration (CCS) has been recognized as a crucial element in the toolkit of measures to combat climate change. At the European Union (EU) level, CCS plays a vital role in climate policy, particularly in reducing CO2 emissions from hard-to-abate industries. However, no comprehensive legal framework covers all stages of CCS. These stages include carbon capture t

Scandinavian countries have a long tradition of widespread public schooling linked to civic education. In the most recent curriculum reforms, concepts from rhetoric appear in various forms in language arts subject curricula from primary to upper-secondary school. In this article, we examine how current Scandinavian curricula reflect rhetoric and rhetorical education through content analysis based

Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and betw