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A life-course study of cognitive reserve in dementia: Dementia incidence in inpatient registers and mmse test scores in a clinical study in sweden

Cognitive reserve helps mitigate the impact of pathology on the clinical expression of dementia. Education and occupational complexity are considered as contributors to reserve, although it has been argued that cognitive reserve is likely formed over the life-course. A life-course model of cognitive reserve in dementia risk has not yet been tested. We apply a life-course model and examine if schoo

Rapid and sustained health utility gain in anti-TNF treated inflammatory arthritis. Observational data during seven years in southern Sweden.

BACKGROUND: Rheumatoid arthritis (RA), psoriatic arthritis (PsA), and other spondylarthritides (SpA) impose great impact on the individual in addition to the costs on society, which may be reduced by effective pharmacological treatment. Industry independent health economic studies should complement studies sponsored by industry. OBJECTIVE: To study secular trends in baseline health utilities in pa

Next generation DNA sequencing of a Swedish Malignant Hyperthermia cohort.

Malignant Hyperthermia (MH) related mutations have been identified in the ryanodine receptor type 1 gene (RYR1) and in the dihydropyridine gene (CACNA1S), but about half of the patients do not have causative mutations in these genes. We wanted to study the contribution of other muscle genes to the RYR1 phenotypes.

High-temperature deformation in the basal shear zone of an eclogite-bearing fold nappe, Sveconorwegian orogen, Sweden

Ductile shear zones associated with emplacement of high-pressure nappes are key features to resolve exhumation mechanisms. The Eastern Segment of the Sveconorwegian orogen hosts an eclogite-bearing fold nappe, whose basal shear zone shows structures associated with emplacement of the eclogite-bearing nappe and decompression under high to intermediate pressure granulite and upper amphibolite fades

The Collective Voice Legitimation Strategies in Focus Group Discussions with Nurses in Municipal Palliative Care for Older People in Sweden

This paper explores focus group discussions of registered nurses in municipal palliative care for older people, using data collected by researchers with an interest in health sciences. The linguisti- cally based discourse analyis builds on a combi- nation of Bakhtinian notions of dialogicity, the Other and addressivity, the use of quotations, and also van Leeuwen’s framework for legitima- tion in

Sociodemographic and disease-related factors are associated with patient-reported anxiety and depression in spondyloarthritis patients in the Swedish SpAScania cohort.

Anxiety and depression are common among patients with rheumatic diseases. This study aims to explore which factors are associated with self-reported anxiety and depression in a well-defined cohort of spondyloarthritis (SpA) patients. In 2009, 3,711 patients from the SpAScania cohort were sent a postal questionnaire to assess health-related quality of life (HRQoL) and physical and mental functionin

Time trends between 1987 and 2007 for perfluoroalkyl acids in plasma from Swedish women.

Perfluoroalkyl acids (PFAAs) are a large group of chemicals which are highly persistent in both nature and humans. The use of the most prominent ones, perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), was reduced in the early 21st century, and since then levels in human matrices have decreased. However, these two compounds have been exchanged by other PFAAs, for which time trends

Chemical composition of Late Svecofennian granite in the Bothnian Basin, central Sweden

Late Svecofennian granite is frequent in the Bothnian Basin, especially in zones of rapidly changing metamorphic grade but also in areas, where the metamorphic grade is elevated. The granite is essentially undeformed, but weakly foliated or lineated rocks are common; more rarely are rocks strongly foliated. X-ray fluorescence was used for major-element and ICP-MS for trace-element analyses. The ch

Clusters of AMI risk factors and their association with left ventricular hypertrophy: A population-based study within the Skaraborg Project, Sweden.

Risk factors for acute myocardial infarction (AMI) are known to cluster and to be differently distributed in men and women. The aim of this study was to sex-specifically explore clusters of acknowledged AMI risk factors by factor analysis, and to study whether such clusters are associated with left ventricular hypertrophy (LVH), used as a subclinical measure of CHD.

Overweight and television and computer habits in Swedish school-age children and adolescents: A cross-sectional study.

The aim of this cross-sectional study was to investigate the prevalence of overweight and obesity in children and adolescents (6-16 years), and relationships between being overweight and sleep, experiencing of fatigue, enjoyment of school, and time spent in watching television and in sitting at the computer. Trained school nurses measured the weight and height of 2891 children aged 6, 7, 10, 14, a

Osteoarthritis and Activity-An Analysis of the Relationship Between Eburnation, Musculoskeletal Stress Markers (MSM) and Age in Two Neolithic Hunter-Gatherer Populations from Gotland, Sweden

The occurrence of osteoarthritis (OA) as an indicator of physical activity was explored in two Middle Neolithic samples from Gotland (c. 3400-2300 BC) in the Baltic Sea: Ajvide (n = 46) and Vasterbjers (n = 32). The difficulty in diagnosing OA is recognised and only eburnation was used as a definite criterion for OA. The relationship between eburnation lesions and Musculoskeletal Stress Markers (M

Risk factors for cardiovascular disease and future osteoarthritis-related arthroplasty: a population-based cohort study in men and women from Malmo, Sweden

Objective: To investigate the hypothesis that cardiovascular risk factors increase the likelihood of future osteoarthritis (OA)-related arthroplasty in adult men and women. Methods: Baseline cohort data on cardiovascular risk factors [age, socio-economic class, family history, obesity, smoking, glucose, cholesterol, blood pressure, and early cardiovascular disease (CVD) history] were linked to cli