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Vilka exportföretag prisdiskriminerar?

Denna studie undersöker företags prisvariation mellan olika exportmarknader. Tidigare studier betonar kvalitetsskillnader som en viktig orsak till variationer i exportpriser. Vi utgår i stället från en alternativ förklaringsmodell som baseras på marknadssegmentering och studerar relationen mellan företagens prisvariation och deras markup. Vi använder detaljerad företags- och produktdata för en hel

Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion.

We previously demonstrated that the overall incretin effect and the β-cell responsiveness to glucagon-like peptide-1 (GLP1) are increased in insulin-resistant mice and may contribute to the upregulated β-cell function. Now we examined whether this could, first, be explained by increased islet GLP1 receptor (GLP1R) protein levels and, secondly, be leveraged by G-protein-coupled receptor 119 (GPR119

Human Embryonic Stem Cell-Derived Mesenchymal Stroma Cells (hES-MSCs) Engraft In Vivo and Support Hematopoiesis without Suppressing Immune Function: Implications for Off-The Shelf ES-MSC Therapies.

Mesenchymal stroma cells (MSCs) have a high potential for novel cell therapy approaches in clinical transplantation. Commonly used bone marrow-derived MSCs (BM-MSCs), however, have a restricted proliferative capacity and cultures are difficult to standardize. Recently developed human embryonic stem cell-derived mesenchymal stroma cells (hES-MSCs) might represent an alternative and unlimited source

Multiterminal multimode spin-dependent scattering matrix formalism: Electron and hole quantum spin transport in multiterminal junctions

We present a derivation of a scattering matrix method providing an exact multimode solution to spin-dependent quantum transport in multiterminal structures. The method is formulated in a general language such that it can readily be applied to any spin-S system with spin interactions. We apply the formalism to spin-1/2 electron and spin-3/2 hole transport in three- and four-terminal structures. It

The implementation of organic principles and values in the European Regulation for organic food

Abstract in Undeterminedhe paper is based on selected findings of the research project EEC 2092/91 (Organic) revision. It contributes to an improved understanding of the core ethical values associated with and principles of organic farming, analyses reference to such values in the European Regulation (EEC) 2092/91 and its ongoing revision, and contrasts them with current practice of organic agricu

Stable operation during pilot-scale anaerobic digestion of nutrient-supplemented maize/sugar beet silage.

Biogas production from maize/sugar beet silage was studied under mesophilic conditions in a continuous stirred tank reactor pilot-scale process. While energy crop mono-digestion is often performed with very long hydraulic retention times (HRTs), the present study demonstrated an efficient process operating with a 50-day HRT and a corrected total solids (TS(corr)) based organic loading rate of 3.4k

Three-dimensional structures of Plasmodium falciparum spermidine synthase with bound inhibitors suggest new strategies for drug design.

The enzymes of the polyamine-biosynthesis pathway have been proposed to be promising drug targets in the treatment of malaria. Spermidine synthase (SpdS; putrescine aminopropyltransferase) catalyzes the transfer of the aminopropyl moiety from decarboxylated S-adenosylmethionine to putrescine, leading to the formation of spermidine and 5'-methylthioadenosine (MTA). In this work, X-ray crystallograp

Specific genetic modifications in the CNS - Cell specific expression and gene specific regulation

Popular Abstract in Swedish Vid genterapi för man in nya gener i en individs celler. Detta kan göras med hjälp av modifierade virus. Dessa virus kan föra in den nya genen, den såkallade transgenen, in i värdcellen men inte bilda nya viruspartiklar. I många fall är det viktigt att begränsa i vilka celler som transgenen uttrycks, då det producerade proteinet kan ge bieffekter i andra celltyper. Det Gene therapy is a promising therapeutic tool for many diseases of the CNS. Lentiviral vectors are particularly attractive since this vector type can transduce both dividing and non-dividing cells, have a relatively large cloning capacity, can sustain long-term transgene expression and have low immunogenicity. The specificity of the vector is however important to avoid potential off-target effects

The Gaia-ESO Survey: New constraints on the Galactic disc velocity dispersion and its chemical dependencies

Context. Understanding the history and the evolution of the Milky Way is one of the main goals of modern astrophysics. In particular, the formation of the Galactic disc is a key problem of Galactic archaeology. Aims. We study the velocity dispersion behaviour of Galactic disc stars as a function of the [Mg/Fe] ratio, which for small metallicity bins can be used as a proxy of relative age. This key

Evaluating safeguards in a conservation incentive program : participation, consent, and benefit sharing in indigenous communities of the Ecuadorian Amazon

Critics suggest that Reducing Emissions from Deforestation and forest Degradation (REDD+) may not generate improvements in well-being for participating stakeholders, and may in fact undermine indigenous rights. To ensure positive social benefits from REDD+ projects, the United Nations REDD Programme has proposed core safeguards, including local stakeholder participation; free, prior, and informed

How to study social media practises in converging library spaces. Making the case for deploying co-­presence ethnography in studies of 2.0-­libraries

Ethnographically inspired methods have in recent years been successfully applied in Information Science (IS) research on different forms of social media related practices (c.f. Sundin & Francke 2009a; 2009b, Kjellberg 2010). This paper aims to contribute to an emerging discussion on the use of this methodological approach for analysing and comprehending consequences of the 2.0-turn in public l

Sedation with ketamine and low-dose midazolam for short-term procedures requiring pharyngeal manipulation in young children

Background: Pediatric intestinal biopsy procedures including considerable transpharyngeal manipulation of a wire-guided metal capsule require adequate sedation or anesthesia. This retrospective cohort study was designed to evaluate intravenous sedation with ketamine and low-dose midazolam in young children undergoing these procedures before and also after discharge from the hospital. Methods: A t

Customer roles in mergers and acquisitions: A systematic literature review

Customers are important stakeholders for any company; yet, they seem not to be widely discussed in merger and acquisition research. This chapter synthesizes the current body of research on customers in mergers and acquisitions through presenting a systematic literature review. The chapter is based on a systematic literature review resulting from a search in EBSCO Host for any research item that re

Isoprene emission from Sphagnum species occupying different growth positions above the water table

Isoprene emission from Sphagnum species naturally growing at different positions above the water table were measured in a subarctic peatland and at monoliths from a temperate bog. Our objectives were to investigate (1) whether emission rates were species and/or moisture dependent, and (2) whether short-term temperature history had an influence on emission capacity. We expected greater emission cap

Improvisation, Computers, and Interaction : Rethinking Human-Computer Interaction Through Music

Interaction is an integral part of all music. Interaction is part of listening, of playing, of composing and even of thinking about music. In this thesis the multiplicity of modes in which one may engage interactively in, through and with music is the starting point for rethinking Human-Computer Interaction in general and Interactive Music in particular. I propose that in Human-Computer interactio

Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy

Tumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven immunosuppression, e.g., through CD25(+) regulatory T cells. We addressed this question in a mouse model of mesothelioma by depleting or reconstituting CD25(+) regulatory T cells in combination with two different chemotherapeutic drugs. We found that the effi