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DNA Binding to Zwitterionic Model Membranes.

This study shows that DNA (linearized plasmid, 4331 base pairs and salmon sperm, 2000 base pairs, respectively) adsorbs to model membranes of zwitterionic liquid crystalline phospholipid bilayers in solutions containing divalent Ca(2+) cations, and also in solutions containing monovalent Na(+). The interaction between DNA and surface-supported model membranes was followed in situ using null ellips

Comparison of bacteria and fungus-binding mesh, foam and gauze as fillers in negative pressure wound therapy - pressure transduction, wound edge contraction, microvascular blood flow and fluid retention.

Bacteria- and fungus-binding mesh binds and inactivates bacteria and fungus, which makes it interesting, alternative, wound filler for negative pressure wound therapy (NPWT). This study was conducted to compare the performance of pathogen-binding mesh, foam and gauze as wound fillers in NPWT with regard to pressure transduction, fluid retention, wound contraction and microvascular blood flow. Woun

Acquisitions and network identity change

Abstract in UndeterminedPurpose - The purpose of the paper is to discuss whether or not an acquisition changes the network identity of an acquired firm and, if so, how. This study aims to bring new insights to the corporate marketing field, as it examines corporate identity in the context of how a company is perceived because of its relationships with other firms. The focus of this research is acq

Five moments in the history of industrialized building

Industrialized building has drawn in ideas from many pioneering researchers during its decades of development; in this brief recapitulation we present some observations on selected moments in the history that have significantly shaped the approach to building construction. The first formative movement identified is prefabrication, as used by Joseph Paxton during construction of the Crystal Palace.

Factor H Autoantibodies in Patients with Antiphospholipid Syndrome and Thrombosis.

Autoantibodies to complement factor H (FH) are associated with atypical hemolytic uremic syndrome, but can also be detected in patients with rheumatoid arthritis and in patients positive for lupus anticoagulants and thus potentially antiphospholipid syndrome (APS). To our knowledge, no data are available on the association between the presence of FH autoantibodies in APS and clinical manifestation

Structural Insights into the Calcium-Mediated Allosteric Transition in the C-Terminal Domain of Calmodulin from Nuclear Magnetic Resonance Measurements.

Calmodulin is a two-domain signaling protein that becomes activated upon binding cooperatively two pairs of calcium ions, leading to large-scale conformational changes that expose its binding site. Despite significant advances in understanding the structural biology of calmodulin functions, the mechanistic details of the conformational transition between closed and open states have remained unclea

Evaluation of selective broadcast algorithms for safety applications in vehicular ad hoc networks

Just as the wireless communication technology develops further to achieve higher performance, new application areas emerge to challenge its limits. Vehicular ad hoc networks are one of these areas; and emergency situation warning is one of their most popular potential applications since traffic safety is a real concern for everyone. Due to the life-critical nature of emergency applications, howeve

Personal grievance sharing, frame alignment, and hybrid organisational structures: the role of social media in North Africa’s 2011 uprisings

The paper develops an analytical framework for understanding the role of social media in the 2011 North African uprisings. It argues that analysis of the role of Facebook, Twitter, and other social media tools should be broken down into two distinct phases: a pre-mobilisation phase and a collective action phase. Using frame analysis and the notion of connective action, the paper demonstrates that

Secondary organic aerosol formation from gasoline passenger vehicle emissions investigated in a smog chamber

Gasoline vehicles have elevated emissions of volatile organic compounds during coldstarts and idling and have recently been pointed out as potentially the main sourceof anthropogenic secondary organic aerosol (SOA) in megacities. However, there is5 a lack of laboratory studies to systematically investigate SOA formation in real-worldexhaust. In this study, SOA formation from pure aromatic precurso

Adsorption of Lipid Liquid Crystalline Nanoparticles: Effects of Particle Composition, Internal Structure, and Phase Behavior

Controlling the interfacial behavior and properties of lipid liquid crystalline nanoparticles (LCNPs) at surfaces is essential for their application for preparing functional surface coatings as well as understanding some aspects of their properties as drug delivery vehicles. Here we have studied a LCNP system formed by mixing soy phosphatidylcholine (SPC), forming liquid crystalline lamellar Struc

HIF-2α Expression Is Suppressed in SCLC Cells, Which Survive in Moderate and Severe Hypoxia When HIF-1α Is Repressed.

Small cell lung carcinoma (SCLC) is extremely aggressive and frequently metastasizes widely in its early stage. Because tumor hypoxia is related to aggressive tumor behavior and the hypoxic adaptation of SCLC is poorly documented, we stained SCLC tumors arranged in a tissue microarray for hypoxia-inducible factor (HIF)-1α and HIF-2α proteins. We found an overall lack of HIF-2α protein expression,

Health policy evolution in Lao People’s Democratic Republic: Context, processes and agency

Abstract in UndeterminedDuring the last 20 years Lao People's Democratic Republic has successfully developed and adopted some 30 health policies, strategies, decrees and laws in the field of health. Still, the implementation process remains arduous. This article aims at discussing challenges of health policy development and effective implementation by contextualizing the policy evolution over time

SOFC Cell Design Optimization Using the Finite Element Method Based CFD Approach

Fuel cells are hopeful for future energy systems, because they are energy efficient and able to use renewable fuels. A coupled computational fluid dynamics approach based on the finite element method, in three-dimensions, is used to illustrate a planar intermediate-temperature solid oxide fuel cell. Governing equations for momentum, gas-phase species, heat, electron and ion transport are implement

On Friendship Between Online Equals

There is an ongoing debate about the value of virtual friendship. In contrast to previous authorships, this paper argues that virtual friendship can have independent value. It is argued that within an Aristotelian framework, some friendships that are prehaps impossible offline can exist online, i.e. some offline unequals can be online equals and thus form friendships of independent value.

Copoly(arylene ether nitrile) and Copoly(arylene ether sulfone) lonomers with Pendant Sulfobenzoyl Groups for Proton Conducting Fuel Cell Membranes

Three series of fully aromatic ionomers with naphthalene moieties and pendant sulfobenzoyl side chains were prepared via K2CO3 mediated nucleophilic aromatic substitution reactions. The first series consisted of poly(arylene ether)s prepared by polycondensations of 2,6-difluoro-2'-sulfobenzophenone (DFSBP) and 2,6-dihydroxynaphthalene or 2,7-dihydroxynaphthalene (2,7-DHN). In the second series, co

Dissociative double-photoionization of butadiene in the 25-45 eV energy range using 3-D multi-coincidence ion momentum imaging spectrometry

Dissociative double-photoionization of butadiene in the 25-45 eV energy range has been studied with tunable synchrotron radiation using full three-dimensional ion momentum imaging. Using ab initio calculations, the electronic states of the molecular dication below 33 eV are identified. The results of the measurement and calculation show that double ionization from π orbitals selectively triggers t