In international research there is a near consensus that the importance of cities is growing. As the policymakers of contemporary cities redirect their policy orientations away from the goal of redistribution towards achieving economic competitiveness, and as they introduce new structures of governance, they are becoming more and more committed to entrepreneurial city politics. However, both the i

To gain entry into target cells, HIV-1 binds to CD4 via the viral glycoprotein gp120. This interac-tion initiates a series of events including binding of a coreceptor, CCR5 and/or CXCR4, and ulti-mately leads to gp41-mediated fusion of the viral and cell membranes. CCR5-restricted (R5) vi-ruses predominate in early, asymptomatic stages of the infection. Emergence of viruses able to use CXCR4 inste

A polygonal finite-element formulation is applied to solve electromechanically coupled inhomogeneous boundary value problems for polycrystalline materials. Each grain is discretised by one single polygonal finite element, which allows the efficient simulation of general boundary value problems which still resolves individual grains in space. The constitutive model proposed for switching in piezoce

Background: Risk factors for hip fracture are well studied because of the negative impact on patients and the community, with mortality in the first year being almost 30% in the elderly. Age, gender and fall risk-increasing drugs, identified by the National Board of Health and Welfare in Sweden, are well known risk factors for hip fracture, but how multimorbidity level affects the risk of hip frac

The position generator is a widespread method for measuring latent social capital in which respondents are queried about contacts on a list of occupations predefined by the analyst. We separate out the unique contribution of each occupation to aggregated measures of social capital. It turns out that this contribution varies vastly: knowing a person in some occupations provides substance to measure

We used molecular dynamics simulation to model the effect of urea and thiourea on the solvent quality of aqueous solutions with respect to cellulose. A model system consisting of a periodically replicated cellulose molecule of effectively infinite degree of polymerization immersed in aqueous (thio-)urea solution was considered. Kirkwood-Buff theory, which relates the pair distribution functions to

Software development companies operating in market-driven domains need to deliver new and appealing software products at an increasing rate in order to stay competitive. This requires fast and efficient development of software for which the requirements are based on ever-changing market demands. Agile development claims to achieve increased development efficiency by performing the requirements eng

In this study, numerical simulations are conducted to investigate the effects of bowed outlet guide vanes (OGVs) on endwall heat transfer and aerodynamic performance. Both on- and off-design conditions are studied. For bowed vanes, the bowed angle varies from 10 degrees to 40 degrees and the normalized bowed height ranges from 0.1 to 0.3. Results are included for Nusselt number distributions on th

A traffic encounter between individual road users is a process of continuous interplay over time and space and may be seen as an elementary event with the potential to develop into an accident. This paper proposes a framework for organising all traffic encounters into a severity hierarchy based on some operational severity measure. A severity hierarchy provides a description of the safety situatio

Laurentia, the core of Paleo- to Mesoproterozoic supercontinent Nuna, has remained largely intact since assembly 2.0 to 1.8 billion years ago [Ga]. For earlier times, previous paleomagnetic data on poorly dated Paleoproterozoic mafic intrusions yielded ambiguous estimates of the amount of separation between key cratons within Nuna such as the Slave and Superior. Recent developments in paleomagneti

Objectives - In patients with large middle cerebral artery (MCA) infarcts, maximum brain swelling leading to cerebral herniation and death usually occurs 25 days after onset of stroke. The study aimed at exploring the pattern of compounds related to cerebral energy metabolism in infarcted brain tissue. Methods - Forty-four patients with malignant MCA infarcts were included after decision to perfor

The present work is based on the Kantian (AaO)-axiom and conceptualised as a textbook. As scientific method in the true sense of the notion science, the Vertex version of Perspective Text Analysis (PTA) represents a completely new approach to text-based studies. The inter-lingual character of Vertex has been tested and established in the context of six different languages, four belonging to the Ge

Wild dabbling ducks (genus Anas) are the main reservoir for influenza A virus (IAV) in the Northern Hemisphere. Current understanding of disease dynamics and epidemiology in this virus-host system has primarily been based on population-level surveillance studies and infection experiments conducted in laboratory settings. Using a combined experimental-natural approach with wild-strain captive malla

Pacini G, Ahren M, Ahren B. Reappraisal of the intravenous glucose tolerance index for a simple assessment of insulin sensitivity in mice. Am J Physiol Regul Integr Comp Physiol 296: R1316-R1324, 2009. First published February 11, 2009; doi: 10.1152/ajpregu.90575.2008.- Mice are increasingly used in studies where measuring insulin sensitivity (IS) is a common procedure. The glucose clamp is labor

This thesis aimed to search for etiological clues about cancer of unknown primary(CUP) by gathering novel information. The Swedish national registries were used and CUP cases were identified according to the seventh revision of the International Classification of Diseases. A consistent increase before the late 1990s and a dramatic decrease afterwards were observed for CUP incidence among Swedes,re

We consider the problem of gray-box identification of dynamic models for mechanical systems. In particular, the problem is approached by means of continuous-time system identification using subspace-based methods based on discrete-time input-output identification data. A method is developed, with the property that the structure of the model resulting from fundamental physical first principles is o

We present an efficient photon-echo experiment based on atomic frequency combs [Phys. Rev. A 79 (2009) 052329]. Echoes containing an energy of up to 35% of that of the input pulse are observed in a Pr3+ -doped Y2SiO5 crystal. This material allows for the precise spectral holeburning needed to make a sharp and highly absorbing comb structure. We compare our results with a simple theoretical model w

This paper aims to highlight the changing and diversifying nature of academic work related to various forms of knowledge production and diffusion. Focusing on the changing research policy landscape in Sweden, three interrelated questions are investigated: what academics do in terms of commercialisation and public dissemination; how they perform these activities; and why they engage in these activi