Background: People with psychosis have a reduced life expectancy of 10-20years, largely due to cardiovascular disease. This trial aimed to determine the effectiveness of a modular health promotion intervention (IMPaCT Therapy) in improving health and reducing cardiovascular risk in psychosis. Methods: A multicentre, two arm, parallel cluster RCT was conducted across five UK mental health NHS trust

Estimation of hydraulic parameters of the vadose zone is a relevant issue in hydrological characterization and flow model calibration. Two borehole Ground Penetrating Radar (GPR) techniques are discussed: Zero-Offset Profiling (ZOP) and Vertical Radar Profiling (VRP). The field case is representative of a very common situation in vadose zone characterization: Above the water table, the permittivit

The European Union’s capacity for leadership is not just decided by the EU itself. It is also affected by the perceptions of other actors regarding the EU’s role, and by their reactions to its initiatives. The same can be said of the Union’s influence in the international arena, including its capacity to do something about global imbalances. Is the EU perceived as a legitimate actor that has somet

The neoliberal notion of employability has risen to prominence over the past 20 years, having been positioned as the crux of national, organizational and individual prosperity. To be employable, individuals are increasingly called upon to be self-reliant; aligning themselves to the conditions of an ostensibly fast-moving and precarious global economy. This special issue of ephemera calls attention

Recently there is an increasing interest in the understanding of the Spectral Induced Polarization (SIP) phenomenon in porous media. The complex electrical conductivity of porous geological materials has a frequency dependent behavior than can be associated to three main mechanisms: Maxwell-Wagner (MW) polarization, Membrane polarization, Electrical double layer (EDL) polarization. This paper aims

Globally, large international research infrastructures have over many decades promoted excellence in science and technology. Aligned with the international practice, the Europe Strategy Forum for Research Infrastructures (ESFRI) has developed and keeps updating a roadmap for research infrastructures. The Extreme Light Infrastructure (ELI) is one of the two large scale Laser Research Infrastructure

REDD is one of the latest additions to a series of incentive-based mechanisms for reducing carbon emissions. Although international negotiations have not eliminated uncertainties regarding its social, economic and political implications, many developing and emerging countries have begun to engage in REDD. Peru, the country with the world’s fourth largest tropical forest area has good reason to par

We investigate the relation between crystal stacking faults in individual wurtzite InAs and GaAs nanowires and the intensity of the forbidden longitudinal optical (LO) phonon mode in the Raman spectra. Micro-Raman spectroscopy and transmission electron microscopy are combined on the same individual nanowires to evaluate the LO mode intensity as a function of the stacking fault density. A clear inc

The observation of neutrinoless double-beta decay (0νββ) would show that lepton number is violated, reveal that neu-trinos are Majorana particles, and provide information on neutrino mass. A discovery-capable experiment covering the inverted ordering region, with effective Majorana neutrino masses of 15 - 50 meV, will require a tonne-scale experiment with excellent energy resolution and extremely

Genetic factors are important in the pathogenesis of osteoporosis and the estrogen receptor has been suggested as a possible candidate gene for regulation of bone mineral density (BMD). We investigated the relationship between PvuII, XbaI, and dinucleotide (TA)n repeat polymorphisms of the estrogen receptor alpha (ER-alpha) gene and BMD in a study of women from northeast Scotland in the United Kin

UNLABELLED: To clarify the role of the TNFRSF11B gene encoding osteoprotegerin (OPG), in Paget's disease of bone (PDB) we studied TNFRSF11B polymorphisms in an association study of 690 UK subjects and in a worldwide familial study of 66 kindreds. We found that the G1181 allele of TNFRSF11B, encoding lysine at codon 3 of the OPG protein, predisposes to both sporadic and familial PDB.INTRODUCTION: P

Information on late onset liver complications after childhood cancer is scarce. To ensure an appropriate follow-up of childhood cancer survivors and reducing late liver complications, the need for comprehensive and accurate information is presented. We evaluate the risk of liver diseases in a large childhood cancer survivor cohort. We included all 1-year survivors of childhood cancer treated in th

The role of soluble human epidermal growth factor receptor (sHER3) in bladder cancer remains unclear. In the present study, an ELISA was developed for the quantification of sHER3 and its role was investigated in patients with bladder cancer (n=82) followed for 10 years. Furthermore, the effects of sHER3 on bladder cancer cell growth and migration were also investigated. The results demonstrated th