RNA interference (RNAi) is a biological gene silencing mechanism that functions in every cell, and has the last two decades become a promising approach for genetic therapeutics. With small interfering RNA (siRNA) complementary to the target gene sequence, the siRNA together with the RNA induced silencing complex (RISC), can degrade the coding mRNA, inhibit protein from translation and thus mediate

I dagens marknad måste akustiktak vara både funktionellt och estetiskt tilltalande. För att uppfylla de behoven har Saint-Gobain Ecophon utvecklat en produkt som heter Focus DS som är ett demonterbart akustiktak med dolt bärverk. Även om Focus DS uppfyller marknadsbehoven har Ecophon upptäckt att där är problem med den nuvarande designen av Focus DS som ofta leder till skador på takplattorna. MåleAcoustic ceilings in today’s market has to be both functional and aesthetically pleasing. In order to fulfill those needs Saint-Gobain Ecophon has developed a product called Focus DS which is a demountable acoustic ceiling with a concealed grid system. Even though Focus DS fulfills the markets needs Ecophon has discovered that there are issues with the current design of Focus DS that often results

Med globalisering och internationalisering har det blivit allt vanligare för företag att skicka chefer eller andra anställda att jobba utomlands. De som skickas kallas för utstationerade. Vissa utstationerade anställda misslyckades med sina uppdrag eftersom de inte kunde anpassa sig till den nya kulturen. Syftet med studien var att undersöka relationen mellan tid i värdlandet, kulturell intelligen

This thesis investigates the options for data logging for PLC:s produced by Automationspartner AB. The thesis investigates the three most common brands of PLC used by Automationspartner, and will for each brand determine which is the most suited, based on criteria provided by the company. This thesis compare a number of solutions but only a few of these are analyzed in greater detail. The thesis r

The aim of the thesis was to build a test environment to be used by the company Cactus Uniview. The test environment should be a tool (software) for testers in the development department, the test environment should be able to ensure the quality of the tool Cactus Eye. Cactus Eye is connected to a PLCs and can be used to control many PLCs. Cactus Uniview uses a virtual test environment (entirely b

Svensk sjöfart har sedan oljekrisen i början av 1970-talet i olika omgångar haft svårt att konkurrera på den internationella marknaden. Svenska rederier har saknat de verktyg som flertalet andra sjöfartsnationer har haft för att kunna hålla nere personalkostnaderna. Dessa verktyg har exempelvis bestått i parallella sjöfartsregister. Svenskt tonnage har därför bekvämlighetsflaggats i register utanfSince the oil crisis in the early 1970s´ the shipping companies in Sweden have faced difficulties in their competition with other seafarer nations. Ship owners in other countries has certain tools in order to keep the employee costs down that the Swedish ships owners don´t have. The tools in question is parallel ships registers that are of a convenient model for the ship owners. As a result of the

Förnybara energikällor och återvunnen energi kan integreras i fjärrvärmenätet genom att ansluta en anläggning ute i nätet för att komplettera den centrala produktionen. Detta har fördelar för det lokala energisystemet som på ett klimatsmart sätt kan säkerställa värmekvalité även långt ut i nätet.The district heating sector is moving into a new era which brings lower temperatures in the heating network which in turn opens up for a more extensive use of low grade heat such as solar heat. This project aims to develop a dynamic simulation model for feeding centrals in order to be able to design and optimize systems for decentralized feeding regardless of heat source. The big challenge lies in

Mutationer avslöjar släktskap mellan celler i människa En generell uppfattning är att en människa skulle bestå av ett genom. Egentligen har vi mellan 30-40 triljoner kopior av genomet, distribuerade i varje enskild cell av vår kropp. Genom att studera mutationer som uppkommer när en cell delar sig kan släktskapet mellan celler undersökas. Vi utvecklar en metod för att kunna hitta dessa mutationerTracing cell lineage has not been considered feasible in humans due to the invasive procedures. However, by analysing somatic mutations acquired during cell division it is possible to compare the relationship between cells within an individual. Knowledge about cell lineage relationships can shed light on the origins of new cells. In order to track cell fate in humans, we are developing a method en

The growth of building energy simulation tools has provided users with a variety of alternatives to model and simulate buildings. The algorithms used in each building energy simulation software are different and range from simple to highly complex. TEKNOsim is a simple design tool based on analytical and empirical algorithms. It is used for calculating building thermal loads and simulating indoor

Background Axis is a network surveillance company, based in Lund, Sweden. Axis has outsourced its production to contract manufacturers which are positioned in different parts of the world. Axis’ suppliers are also spread across the globe. During the last years, Axis has experienced several supply disruptions from its suppliers and contract manufacturers, due to natural and technological disasters.

Studien fokuserar på att kartlägga svenska lärares benägenhet inför att vidarebefordra information om oegentligheter i den egna verksamheten, samt presentera skillnader i sådan benägenhet mellan privat och offentligt anställda. Studien bygger på de begrepp och resonemang som presenteras i Lennart Lundquists Demokratins väktare. Studiens empiriska material består av enkätsvar från 194 anonyma lära

The purpose of this thesis is to explore the relationship between gendered vulnerabilities and well-being outcomes in the face of climate change by introducing a consolidated gender and vulnerability framework as a tool to highlight and assess underlying power structures determining women’s adaptive capacity. The thesis first focuses on women’s perception of climate signals and its direct and indi

I denna uppsats studeras Egypten specifikt. Syftet är att ta reda på vilka klassbaserade motsättningar som fanns i Egypten som ledde fram till Mubaraks fall år 2011. Studien är teorianvändande och utifrån ett klassperspektiv tillämpar vi begrepp som våldsmonopol, klass ojämlikhet och demokrati, klasskonstellationers relation till demokratisering, klassintressen och kollektiv aktion, konceptualiser

Over the past decade, the artworld has seen the emergence of various new art genres such as post-internet art, post-media art, and Internet-aware art to name a few. What these genres insinuate is an era of transition between us and digital media, between our online sphere and our offline sphere. This development affects all agents of the artworld, namely, the gallery system, the art-market and mos

Syftet med denna studie är att undersöka hur begreppet kulturell kompetens påverkar arbetsgruppers teamwork i mångkulturella hospitality-verksamheter. Genom studien vill vi skapa en förståelse för hur kulturell kompetens formar och påverkar teamworkprocessen (gruppmedlemmarnas sätt att interagera och kommunicera samt deras olika attityder och beteendemässiga skillnader), för att därmed ge förutsät

Due to the rise of support for Populist Radical Right parties in nations around Europe during the past two decades, the circumstances which allow these new parties to emerge have been recurrently highlighted in academic research, and the ensuing debate has long been dominated by competing theories on when, how and why these changes occur. By shifting focus from the nations in which these new parti

White-light spectra of different crystals, based on 1030-nm intense pump pulses have been investigated in order to derive a near-infrared seed for mid-infrared generation. Among ten crystals, YAG (yttrium aluminium garnet), KGW (potassium gadolinium tungstate) and YVO4 (yttrium orthovanadate) exhibit the most suitable properties for supercontinuum generation with high efficiency for spectral broad

Adolescent sexual and reproductive health is crucial to sustainable development. Regional and national trends emphasise the need to address this issue. Despite national efforts, Mexico continues to have high rates of adolescent birth rates. Insufficient sex education seems to be among the factors contributing to these high rates. According to effective interventions, the integration of Comprehensi