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Popular Abstract in Swedish Galektin är en proteinfamilj med många funktioner i kroppen, varav en del är kopplade till sjukdomstillstånd, såsom inflammationer samt utvecklandet och fortskridandet av cancer. Galektiners funktion styrs av en kolhydratbindande domän (CRD) som känner igen och binder till galaktos. Vissa galektiner kan hålla ihop olika celler genom att binda till galaktos på cellytor.This thesis describes the design, synthesis and evaluation of synthetic inhibitors for the carbohydrate binding proteins called galectins. Potent and selective inhibitors can be used as important research tools in the endeavor to chart the true role of galectins in biological events such as cancer and inflammation and possibly as lead for future galectin targeting drugs. A panel of O-galactosyl a

Popular Abstract in English Enzymes are nanometer sized work units made up of proteins. Each of the thousands of the existing enzymes are produced by the cells of every living organism. They carry out certain functions as putting molecules together, e. g. connect sugar units to form cellulose for a growing tree or destroy molecules, e. g. degrade cellulose into its sugar units to eat and live on tCellobiose dehydrogenase (CDH) is a sugar oxidizing enzyme secreted by various species of wood degrading fungi to assist the process of wood degradation. It can oxidise analytically relevant sugars as cellobiose, lactose or glucose leading to a gain of two electrons per sugar molecule. CDH consists of a flavin containing catalytic domain (DH) and a haem containing electron mediating domain (CYT).

Med temat program och praktik vill vi särskilt uppmana forskare att reflektera över vad som sägs och vad som görs inom hälso-, medicin- och sjukdomsrelaterade verksamheter, såväl i nutid som i det förflutna. Med program avses till exempel vårdpolitiska uttalanden och viljeyttringar av olika slag, beskrivningar eller bilder av hur t.ex. vård och omhändertagande bör vara beskaffad, läroböckers besk

The effect of a certain aggressive action is often aggravated if another aggressive action takes place at the same time. Examples of mechanisms with synergy are (i) salt-frost scaling and reinforcement corrosion, (ii) alkali silica reaction (ASR) and internal frost damage, (iii) leaching of lime and internal frost attack, (iv) leaching of lime and reinforcement corrosion, (v) internal frost and le

We study the effects of local vertex corrections to the self energy of the electron gas. We find that a vertex derived from time-dependent density-functional theory can give accurate self energies without including the explicit time dependence of the exchange-correlation potential provided, however, that a proper decay at large momentum transfer (large q) is built into the vertex function. (The lo

The paper examines the metaphysical ideas employed to embed Hellenistic astrology in an Indian religious and cultural context, relating them to questions of causality, determinism and moral freedom. These ideas are contrasted against the largely Thesophical adaptation of the same concepts, which in the 19th and 20th centuries formed the emerging modern astrology in Europe, and which led it to aban

Popular Abstract in Swedish Inom växtriket finns det ca 3000 arter som är parasitiska och dessa växer i nästan alla större ekosystem på land. Parasitiska växter kan delas in på olika sätt, helparasiter respektive halvparasiter. Denna indelning baserar sig på om de saknar klorofyll och tar all sin näring från sin värdväxt (helparasiter) eller har klorofyll och kan själva framställa kolhydrater men Parasitic plants are found in nearly every major terrestrial ecosystem and can be divided into two groups, holoparasites (lacking chlorophyll) and hemiparasites (chlorophyllous). The host-parasite connection is either situated above (stem parasites) or below ground (root parasites). In this thesis I examine the host-parasite interactions, host range and selection, and population dynamics of four r

In the chapter, “Trade Unions and Collective Agreements in a Changing World”, Anders Kjellberg explains why Swedish union density still is very high from an international perspective and why it fell dramatically in the years 2007 and 2008, particularly among Young and foreign-born employees, both containing a high share of precarious workers. Also, a number of long-term factors pressing union dens

Många idéer cirkulerar kontinuerligt inom och mellan olika fält i samhället. En del av dessa idéer blir på modet och betraktas som legitima lösningar på olika slags problem. Bland dessa kan organisationer – såväl offentliga som privata - lätt hitta färdiga paketlösningar till hur de exempelvis skall styra, leda eller budgetera sin verksamhet. Kvalitetssäkring blev en sådan idé på modet inom hälso-