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Effects of dyadic work organization on realism in confidence judgments

This study examines the effect of three regimens (organizations of activities) on the realism in dyad’s confidence judgments. The effect of letting the pair members first work alone when selecting an answer and/or when confidence rating the correctness of this answer was compared with working directly in pairs. No improvement in the realism of the dyads’ final confidence judgments was found as an

Heat transfer through a well insulated external wooden frame wall : an investigation of the effects of normal defects in the insulation resulting from incident wind and air flow through the wall

The heat requirement of a building can turn out to be greater than was calculated at the design stage. The reason for this may be that heat transport though the building envelope is greater than expected. This in turn can be due to the structure not fulfilling the design requirements in respect of windtightness and airtightness. In addition, there may be defects in the quality of the workmanship o

Exploring light-cone sum rules for pion and kaon form factors

We analyze the higher-twist effects and the SU(3)-flavor symmetry breaking in the correlation functions used to calculate form factors of pseudoscalar mesons in the QCD light-cone sum rule approach. It is shown that the Ward identities for these correlation functions yield relations between twist-4 two-and three-particle distribution amplitudes. In addition to the relations already obtained from t

INVASIVE BLADDER CANCER - Aspects on staging and prognosis

Background: The difficulty of determining the prognosis for the individual patient with invasive bladder cancer is a major clinical problem. Currently, decisions regarding therapy are mainly based on tumour stage and grade, the first of which is notoriously demanding to ascertain. New molecular markers are however proposed to be of prognostic value. At present, there is considerable debate regardi

Thrombogenicity of metallic vascular stents in arteries and veins--an experimental study in pigs

Endovascular expanding metallic stents were percutaneously implanted in the iliac arteries and veins of pigs. The vessels had been stenosed by a ligature of catgut 4 weeks prior to this. Platelets were labeled with Indium 111 and the deposition onto the dilated and stented areas was dynamically registered for 240 min with a scintillation camera. All six arterial and six venous stents remained pate

Djupanalys av tre storbränder

This report presents an analysis of three major fires in Sweden. Two of the fires concerns the industry and the third is a fire in a assembly hall. The study is based on available written material. The quality and reliability varies, and appears to depend on the aim, interest and competence of the investigator. In some cases, the information is sufficient to assess the performance of an automatic

Costimulation Blockade-Induced Cardiac Allograft Tolerance: Inhibition of T Cell Expansion and Accumulation of Intragraft cD4+Foxp3+ T Cells.

Background. Previous studies have demonstrated that anti-CD40L or anti-B7 requires the presence of CD4(+)CD25(+) regulatory T cells (Treg) to induce antigen specific hyporesponsiveness. Other tolerance strategies involving Treg have shown a dependency on interleukin (IL)-10. The objective of this study was to investigate the role of CD4(+)CD25(+) Treg and IL-10 when treating transplant recipients

Bradykinin-induced airflow obstruction and airway plasma exudation: effects of drugs that inhibit acetylcholine, thromboxane A2 or leukotrienes

1 The mechanisms behind bradykinin-induced effects in the airways are considered to be largely indirect. The role of cholinergic nerves and eicosanoids, and their relationship in these mechanisms were investigated in guinea-pigs. 2 The role of cholinergic nerves was studied in animals given atropine (1 mg kg-', i.v.), hexamethonium (2 mg kg-', i.v.), or vagotomized. To study the role of eicosanoid

Regulation of phospholipase D activity in neuroblastoma cells

The regulation of phospholipase D was studied in human neuroblastoma cells using phosphatidylethanol as a marker of the enzyme activity. Carbachol induced phospholipase D activity in SH-SY5Y cells. Muscarinic antagonists inhibited the response with potencies suggesting that muscarinic M1 receptors are responsible for the activation. In permeabilized SH-SY5Y cells, both the carbachol- and GTP gamma

Lysophosphatidic Acid Binds to and Activates GPR92, a G Protein-Coupled Receptor Highly Expressed in Gastrointestinal Lymphocytes

Here, the ligand binding, activation, and tissue distribution of the orphan G protein-coupled receptor (GPCR) GPR92 were studied. GPR92 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity (K(D) = 6.4 +/- 0.9 nM) and led to an increase in both phosphoinositide hydrolysis and cAMP production. GPR92 is atypical in tha

Intracellular signaling and cellular plasticity in a rat model of L-DOPA-induced dyskinesia

Popular Abstract in Swedish Parkinsons sjukdom beror på att de dopamin-producerande cellerna i hjärnan dör. Detta leder till minskad rörlighet, svårigheter i att påbörja och avsluta en rörelse, balanssvårigheter och darrningar (tremor) hos de drabbade patienterna. Varför dopamincellerna dör är oklart och i nulägat kan man inte bota Parkinsons sjukdom, men man kan lindra symptomen med mediciner. PaParkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. This works very well during the initial treatment period, but unfortunately a majority of the patients develop abnormal involu