The liquid biopsy has the potential to improve current clinical practice in oncology byproviding real-time personalized information about a patient’s disease status and response to treatment. In this study, we evaluated 161 peripheral blood (PB) samples that were collected aroundsurgical resection from 47 metastatic colorectal cancer (mCRC) patients using the High-DefinitionSingle Cell Assay (HDSC

We introduce the combination of digital holographic microscopy (DHM) and antibody microarrays as a powerful tool to measure morphological changes in specifically antibody-captured cells. The aim of the study was to develop DHM for analysis of cell death of etoposide-treated suspension cells. Results/methodology: We demonstrate that the cell number, mean area, thickness and volume were noninvasivel

This thesis investigated the modeling and control problems in the context of the flex-fuel compression-ignition (CI) engine and fuel cell, which shows great potential in the transition from fossil fuel to renewable energy sources.The modeling parts included the flex-fuel engine combustion process and intake system, and the system scale fuel cell model.The flex-fuel engine gas system models describ

Även om de politiska kriserna i Belarus och Kazakstan redan är under åtminstone tillfällig kontroll är de liksom ökande politiska spänningar i Ryssland avgörande för att förstå Putins paranoia. Det skriver Tomas Sniegon, historiker och docent i Europastudier vid Lunds universitet.

Significance Our results demonstrate the existence of early cellular pathways and network alterations in oligodendrocytes in the alpha-synucleinopathies Parkinson's disease and multiple system atrophy. They further reveal the involvement of an immune component triggered by alpha-synuclein protein, as well as a connection between (epi)genetic changes and immune reactivity in multiple system atrophy

This study uses numerical experiments to investigate initial breakup morphology for conditions similar to those experienced in an emulsification device (e.g., a high-pressure homogenizer) (Reλ = 33, We = 1–30, μD/μC = 22, ρD/ρC = 0.9, D/η = 22). Results show breakup consisting of two phases: and ‘oscillatory phase’ where the drops are periodically deforming and relaxing, followed by a ‘critical de

The aim of the study is to (i) evaluate a method, based on the normalized difference vegetation index (NDVI) calculated from Landsat TM data, for estimation of tree canopy cover in semi-arid environments and (ii) determine canopy cover changes in a forest area in the Sudan by applying the method on Landsat MSS data from 1972 and 1979. Primarily, the NDVI based method was applied on NDVI values, ca

In a non-negligible number of patients with metastatic colorectal cancer (mCRC), the peritoneum is the predominant site of dissemination. Cure can be achieved by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), but this procedure is associated with long-term morbidity and high relapse rates. Thus, there is a pressing need for improved therapeutic strategies and co

Wastewater sludge represents an important resource for reuse in agriculture. However, potentially harmful pathogens are a main threat in this context. Thus, the aim of this study was to examine the presence of helminth ova and protozoan cysts in dried sewage sludge samples collected from ten wastewater treatment plants (WWTPs) located in eight governorates in Tunisia. Based on morphological criter

PURPOSE: Fibromyalgia (FM) is a complex pain condition, and exercise is considered the first option of treatment. Few studies have examined the effect of exercise on molecular mechanisms in FM. The aim of this study was to analyze the plasma proteome in women with FM and healthy controls (CON) before and after 15 wk of resistance exercise. This study further investigated whether clinical and exerc

Clinical outcome data of patients discharged after Coronavirus disease 2019 (COVID-19) are limited and no study has evaluated predictors of cardiovascular prognosis in this setting. Our aim was to assess short-term mortality and cardiovascular outcome after hospitalization for COVID-19. A prospective cohort of 296 consecutive patients discharged after COVID-19 from two Italian institutions during

According to the Swedish Enforcement Code a debtor is presumed to be the sole owner of movable property which is possessed jointly with a spouse or domestic partner. In my thesis, I investigate this statutory presumption of ownership from a family law perspective. The applicability of the statutory presumption as well as its legal repercussions are determined by family law. It is therefore surprisAccording to the Swedish Enforcement Code a debtor is presumed to be the sole owner of movable property which is possessed jointly with a spouse or domestic partner. In my thesis, I investigate this statutory presumption of ownership from a family law perspective. The applicability of the statutory presumption as well as its legal repercussions are determined by family law. It is therefore surpris