A 76-year-old man presented with cognitive symptoms, followed by headache and weakness of the lower limbs and left arm. The clinical course was progressive but fluctuating. On magnetic resonance imaging (MRI), a contrast-enhancing lesion 1 cm in diameter was seen in the left temporal lobe. This lesion became attenuated and a new contrast-enhancing lesion 1 x 2 cm was seen in the left frontal lobe

BACKGROUND: Muscle weakness is the most common impairment in the upper extremity after stroke, leading to a reduced ability to use the arm and the hand in daily activities. Grip strength is easier to measure than precise, but more time-consuming, isokinetic and isometric arm muscle strength measurements. It would therefore be advantageous in a clinical setting if grip strength could be used as a p

WNT5A is a secreted signaling protein that promotes migration and invasion of oral squamous cell carcinoma (OSCC) cells through activation of non-canonical WNT signaling. Here, we examined expression of WNT5A, β-catenin, and E-cadherin by immunohistochemistry in 21 human diagnostic incision biopsies that each had regions of oral mucosa with a normal appearance adjacent to the affected tissue, dysp

A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying tau lepton has been performed using 3.2 fb-1 of proton–proton collision data at s=13TeV recorded by the ATLAS detector at the Large Hadron Collider in 2015. Two exclusive final states are considered, with either exactly one or at least two tau leptons. No excess over the Standa

The Raheen Formation at Newtown Head in Waterford Harbour is a small isolated section of Ordovician rocks, dominated by volcanics of the Duncannon Group, but with interbedded fossiliferous shales. Although a brachiopod and trilobite dominated fauna has been known since the mid-nineteenth century, only the trilobites and cystoids have been assessed in modern terms. This paper describes the brachiop

Grainyhead-like 2 is a human homolog of Drosophila grainyhead. It inhibits epithelial-to-mesenchymal transition that is necessary for cell migration, and it is involved in neural tube closure, epithelial morphogenesis, and barrier formation during embryogenesis by regulation of the expression of cell junction proteins such as E-cadherin and vimentin. Cancer shares many common characters with devel

For a collection to be considered as such, and not appear only as a clutter or jumble of things, it has to be based on some kind of selection and systematisation. The research question of this article is how and why collectors structure their collections, organise, and arrange them. The research material is answers to the directive “Collecting things”, presented by the Mass Observation Archive in For a collection to be considered as such, and not appear only as a clutter or jumble of things, it has to be based on some kind of selection and systematisation. The research question of this article is how and why collectors structure their collections, organise, and arrange them. The research material is answers to the directive “Collecting things”, presented by the Mass Observation Archive in

Cross section and S factor of the proton- and alpha-induced reactions have been studied for the Ruthenium and tin isotopes in the effective energy range, i.e. Gamow window. These reactions are important for developing the understanding for nucleosynthesis, particularly for the synthesis of p nuclei (p process). In this work, cross sections and S factor have been calculated through TALYS in Hauser–

Initial exertion of self-control has been suggested to impair subsequent self-regulatory performance. The specific cognitive processes that underlie this ego depletion effect have rarely been examined. Drawing on the dual-process theory of executive control (Engle & Kane, ; Kane & Engle, ), the current meta-analysis revealed that initial self-control exertion impairs participants' capaciti

A search for Higgs-boson pair production in the bbbb final state is carried out with 3.2 fb-1 of proton-proton collision data collected at s=13 TeV with the ATLAS detector. The data are consistent with the estimated background and are used to set upper limits on the production cross section of Higgs-boson pairs times branching ratio to bbbb for both nonresonant and resonant production. In the case

The Bacillus subtilis hemAXCDBL operon encodes enzymes for the biosynthesis of uroporphyrinogen III from glutamyl-tRNA. The function of the hemX gene product was studied in this work. The deduced amino acid sequence suggests HemX to be an integral 32 kDa membrane protein. This was confirmed by experiments using Escherichia coli minicells and hemX-phoA gene fusions. Deletion of the hemX gene from t

The citric acid cycle (CAC) has several functions in aerobic bacteria. Together with the pyruvate dehydrogenase multienzyme complex (PDHC), it completely oxidizes pyruvate and provides membrane-bound respiratory systems with reducing equivalents. An overview of the biochemistry and genetics of CAC enzymes in B. subtilis is presented in this chapter. B. subtilis, being a strict aerobe, runs a compl

Bacillus subtilis cells must have cytochromes for growth and can synthesize cytochromes of a-, b-, c-, d-, and o-types. After a long lag, our knowledge of the structure, genetics and specific role for these cytochromes is now growing exponentially as the result of recent research. This progress is reviewed here and includes, for example, the discovery of two different cytochrome a systems and gene

Cytochrome 5558 in the cytoplasmic membrane ofBacilius subtiiis constitutes the anchor and electronacceptor to the flavoprotein (Fp) and iron-sulphurprotein (Ip) in succinate:quinone oxidoreductase, andseemingly contains two haem groups. EPR and MCDspectroscopic data indicate bis-imidazole ligation ofthe haem. Apo-cytochrome was found in the mem-brane fraction of haem-deficient B. subtilis, sugges

The determination of proteins utilising a polymer-based restricted access support material with ion exchange properties (IERAM) is outlined. Solid phase extraction coupled on-line with a microbore reversed phase HPLC system for the quantitation of small marker proteins is demonstrated. The cation-exchange restricted access packings were characterised with respect to their adsorption and desorption

The main question that guides this paper is how governments are focusing (and must focus) on competence building (education and training) when designing and implementing innovation policies. With this approach, the paper aims at filling the gap between the existing literature on competences on the one hand, and the real world of innovation policy-making on the other, typically not speaking to each

Nanoscale plasmonic systems combine the advantages of optical frequencies with those of small spatial scales, circumventing the limitations of conventional photonic systems by exploiting the strong field confinement of surface plasmons. As a result of this miniaturization to the nanoscale, electron microscopy techniques are the natural investigative methods of choice. Recent years have seen the de

The German Federal State of Saxony aims to increase forest cover, supported by the implementation of afforestation programs. To analyze consequences of an increase in forest cover, this study investigates possible trade-offs between carbon storage and plant biodiversity caused by afforestation. Six afforestation scenarios with total forest cover ranging from 27.7% to 46% were generated in the Muld