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Deeply lonely in the borderland between childhood and adulthood - Experiences of existential loneliness as narrated by adolescents

Background: Adolescence is associated with different feelings and experiences that can negatively affect adolescents’ health and well-being. In the transition between childhood and adulthood, experiences of loneliness are common. A deep form of loneliness is described as existential loneliness. Studies among adults have shown that existential loneliness often arises in connection with transitions

(O)möjligheter : Den papperslösa diplomaten Carl Gyllenborgs agens 1715

Professionaliseringen av diplomatin skedde genom en lång process vars start ofta placeras vid slutet av den Westfaliska freden och 1700-talets slut. Denna professionaliseringsprocess var komplex eftersom den formades av de aktiva diplomaterna, deras livserfarenheter, och av tidsspecifika normer förankrade i ritualer och dokumentation, samt därtill av förändringar kopplade till allt tydligare socia

Enabling Decentralized Computation of the WAX Decomposition

As the number of antennas scales up, research efforts have been directed towards finding decentralized receiver solutions for multi-antenna architectures. In a recent paper, a novel matrix decomposition - the WAX decomposition - was proposed, which has direct bearing on characterizing the level of decentralization that is possible if the complexity of the decentralized processing is limited. Howev

Solar access indicators for urban planning

Solar access describes the amount and distribution of sunlight in living environments. Access to sunlight is crucial for the health and sustainability of cities. It is vital for people and vegetation, and for energy production and conservation. The amount of sunlight entering the city space is restricted by the urban layout, as buildings obstruct solar access by shading each other and the surround

The European Solar Telescope

The European Solar Telescope (EST) is a project aimed at studying the magnetic connectivity of the solar atmosphere, from the deep photosphere to the upper chromosphere. Its design combines the knowledge and expertise gathered by the European solar physics community during the construction and operation of state-of-the-art solar telescopes operating in visible and near-infrared wavelengths: the Sw

Infrared Drying Characteristics and Quality Variations of Lily Bulbs Under Blanching Pretreatment

Infrared drying characteristics and quality variations (color change, hardness, contents of polyphenol and flavonoid) of lily bulbs under blanching pretreatment are investigated. Influences of parameters such as pretreatment temperature and time and infrared drying temperature are discussed. Effective moisture diffusivity coefficient, activation energy, and energy consumption were calculated. Resu

Hippocampal subregional thinning related to tau pathology in early stages of Alzheimer’s disease

Background: Subregions in the medial temporal lobe (MTL) are affected early by Alzheimer’s disease (AD) pathology and subject to grey matter atrophy. Measuring the earliest AD-related atrophy in the hippocampus is challenging as region-of-interest (ROI) analyses of hippocampal subregional volumes collapse across voxels within anatomical subregions. PET imaging studies, however, report accumulation

Queering Community : Affect of Visuality in the Sinosphere

How do Chinese queer artists respond to the hegemony of Han-centric, patriarchal, and heterosexual norms, and how do they imagine home through a queer and activist lens? This study explores the visual representation of the queer community by veteran artist/activist couple Shitou and Mingming through an analysis of the photographs and documentaries shot by the artists and their friends since the 19

Evaluating the DICE method to improve early recognition and treatment of neuropsychiatric symptoms in early Alzheimer’s disease

Background: While neuropsychiatric symptoms (NPS) are common in early Alzheimer’s disease (AD), they are currently underdiagnosed and undertreated in the memory clinic. Therefore, we evaluated the effectiveness of the Describe, Investigate, Create, Evaluate (DICE™) approach to structure and standardize the care for NPS in AD in the memory clinic. Method: A total of 60 community-dwelling patients w

Quantifying AD-related brain amyloid with linearised progression models : model-based vs. data-based.

Background: Brain amyloid-β (Aβ) is the pathological hallmark of Alzheimer's disease (AD). In logistic disease models, Aβ accumulation is a sigmoid function of time-since-disease-onset (TSDO) (figure 1). Previous positron emission tomography (PET)-based models vary accumulation onset(t50) and duration(r) globally; capacity(K) and baseline(NS) regionally (Whittington2018). We confirm existing appro

Unraveling the Reaction Mechanism of Mo/Cu CO Dehydrogenase Using QM/MM Calculations

Some microorganisms, like the aerobic soil bacteria, Oligotropha carboxidovorans, have the capability to oxidize the highly toxic atmospheric gas carbon monoxide (CO) into CO2 through CO dehydrogenase enzymes, whose active site contains a bimetallic MoCu center. Over the last decades, a number of experimental and theoretical investigations were devoted to understanding the mechanism of CO oxidatio