Update of the fracture risk prediction tool FRAX : a systematic review of potential cohorts and analysis plan
SummaryWe describe the collection of cohorts together with the analysis plan for an update of the fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource comprises 2,138,428 participants with a follow-up of approximately 20 million person-years and 116,117 documented incident major osteoporotic fractures.IntroductionThe availability of the fracture risk asse