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Tourism challenges within a high cost of living crisis

Living costs have been increasing at an unprecedented rate compared to average trends over the last decade due to increasing uncertainty from various global events, including the COVID-19 pandemic and geopolitical tensions. Previous research indicates that people prioritize essential consumption over leisure and tourism activities during high cost-of-living crises. However, prior studies have over

LNLS vacuum system commissioning

The Brazilian National Synchrotron Light Laboratory, LNLS, operates a synchrotron light source consisting of a 1.37 GeV electron storage ring and a 120 MeV injector. A summary of the commissioning and operation performance of the vacuum system for the linear accelerator (LINAC), transport line, RF system and storage ring is presented. The performance of the subsystems is described including the ph

Commissioning and operation of the Brazilian synchrotron light source

The Brazilian National Synchrotron Light Laboratory, LNLS, operates a 1.37 GeV electron storage ring with a 120 MeV injector Linac. Commissioning of the storage ring at low energy started on May 1996 and now, an year later, we can store 120 mA at 120 MeV and ramp more than 75 mA to 1.37 GeV. A summary of the latest commissioning results and a description of the present operational performance of t

Food loss and waste reduction by using industry 4.0 technologies: examples of promising strategies

Food loss and waste represent a significant global issue, posing a threat to food sustainability on a worldwide scale. Approximately one-third of the food produced for human consumption is wasted, resulting in substantial environmental impact and economic loss. However, the growing awareness among consumers and the development of emerging technologies driven by the 4th Industrial Revolution (Indus

Altered medial temporal lobe subregion volumes in systemic lupus erythematosus patients with neuropsychiatric symptoms

Background: Systemic lupus erythematosus (SLE) often presents with neuropsychiatric (NP) involvement, including cognitive impairment and depression. Past magnetic resonance imaging (MRI) research in SLE patients showed smaller hippocampal volumes but did not investigate other medial temporal lobe (MTL) regions. Our study aims to compare MTL subregional volumes in SLE patients to healthy individual

Vacuum system for the LNLS 500-MeV booster synchrotron

We present a summary of the commissioning and performance of the vacuum system of a 500-MeV booster synchrotron recently built at LNLS as part of a new injector for the LNLS light source. The main vacuum parameters of the synchrotron are pressure below 5×10-7Pa (lifetime of 1-2 hours), no in-situ baking, no cooling system, and a short recovery time after ventilation. All parts of the system are ma

Commissioning of the LNLS 500-MeV booster synchrotron

We present results of the commissioning of a new injector for the Brazilian Synchrotron Light Source. The new injector consists of the existing 125-MeV LINAC and a new 500-MeV booster synchrotron. At present, about 40 mA can be injected into the booster and about 15 mA can be ramped up to 500 MeV at a repetition rate of 0.17 Hz. The new injector has allowed the accumulation of up to 540 mA in the

Preparation and characterization of Ti-Zr-V non-evaporable getter films to be used in Ultra-high acuum

An appealing procedure to obtain operating pressures in the 10-8 Pa range, which is necessary for the insertion devices elements of synchrotron sources, is to coat the inner ultra-high vacuum chamber walls with a thin film of non-evaporable getter (NEG) metals. Titanium, zirconium, vanadium, and their alloys are used as NEG materials due to their low activation temperature, high chemical activity,

Viremia Does Not Independently Predict Cardiovascular Disease in People With HIV : A RESPOND Cohort Study

BACKGROUND: HIV viremia has been considered a cardiovascular disease (CVD) risk factor, but many studies have had insufficient data on potential confounders. We explored the association between viremia and CVD after adjusting for established risk factors and analyzed whether consideration of viremia would improve CVD prediction.METHODS: Adults from RESPOND were followed from the first date with av

Computational Approaches for Antimicrobial Peptide Delivery

Peptides constitute alternative molecules for the treatment of infections caused by bacteria, viruses, fungi, and protozoa. However, their therapeutic effectiveness is often limited by enzymatic degradation, chemical and physical instability, and toxicity toward healthy human cells. To improve their pharmacokinetic (PK) and pharmacodynamic (PD) profiles, novel routes of administration are being ex

Anemia in patients ten years after bariatric surgery

Background: More than 10% of the global population has a BMI above 35. Bariatric surgery is an efficient way to treat this condition. Unfortunately, there is a risk of nutritional deficiencies. The number of studies after a longer time span is scarce. The aim of this study was to determine the occurrence of anaemia five and ten years after bariatric surgery and how it was related to substitution t

Everything-cleft constructions in spoken British English : A neglected construction

Within the framework of Construction Grammar, this study examines constructions with a cleft form containing everything, e.g., that’s everything that’s happened, in spoken British English, using the London-Lund Corpora and the British National Corpora. We trace the development of everything-clefts in recent history and make comparisons with all-clefts since both all and everything express totality

Optimization of Drying Parameters for Pretreated Green Banana Slices Using Response Surface Methodology

In this study, the influence of drying temperature and pretreatment on the drying kinetics and quality metrics of green banana slices was investigated. The present investigation included the drying of 4 ± 1 mm green banana slices with potassium metabisulfite (KMS) at levels of 0 (control), 0.5%, 1%, and 1.5% in a tray dryer. A numerical optimization method was utilized to optimize the drying rate,

When Are Single Reader Evaluations Insufficient in Teledermoscopic Assessments? : Analyses of a Retrospective Cohort Study

Background: Teledermoscopy (TDS) emerges as an efficient tool for diagnosing skin lesions. In Sweden, double reading is the standard of care, but risk factors for misdiagnosis or mismanagement using single reader evaluations (SRE) are not well-studied. This study aimed to assess the accuracy of SRE compared with the gold standard in TDS. Methods: This retrospective cohort study involved 1,997 TDS