Animal movement acts at multiple scales: it can shape the destiny of individuals and populations, govern community and ecosystem structure, and influence evolutionary processes and patterns of biodiversity. Recent technological advances, such as the revolutionary developments in tracking technology and remote sensing, provide fresh insights and the possibility to collect detailed data on where and

Within recent years, there has been a renewed focus on sound in urban environments. From sound installations in public space to sound festivals in alternative settings, we find a common interest in sound art relating to the urban environment. Artworks or interventions presented in such contexts share the characteristics of site specificity. However, this article will consider the artwork in a broa

Background: Cannulation of the internal jugular vein may be associated with inadvertent puncture of the common carotid artery. Systematic use of ultrasound guidance has improved clinical success rates and reduced complications, but better knowledge of topographic relationships of the internal jugular vein and common carotid artery is desirable. This preclinical study was designed to determine by u

Heat loss is one of the greatest energy losses in engines. More than half of the heat is lost to cooling media and exhaust losses, and they thus dominate the internal combustion engine energy balance. Complex processes affect heat loss to the cylinder walls, including gas motion, spray-wall interaction and turbulence levels. The aim of this work was to experimentally compare the heat transfer char

Avhandlingen fokuserar på ojämförbarhet med avseende på värde. Jag avser att förklara varför det ibland kan vara svårt att jämföra vissa objekt. I min avhandling argumenterar jag för att det är språklig vaghet som ger upphov till ojämförbarhet. Jag diskuterar även andra saker så som: huruvida "bättre än" en transitiv relation, om det finns mer relationer än "bättre än", "sämre än" och "lika bra", This thesis explores whether the three standard value relations, “better than”, “worse than” and “equally as good”, exhaust the possibilities in which things can relate with respect to their value. Or more precisely, whether there are examples in which one of these relations is not instantiated. There are cases in which it is not obvious that one of these relations does obtain; these are referred

The osphradium is a putative chemosensory organ of aquatic molluscs. Previously, we identified two distinct types of primary sensory neurons in the osphradial ganglion of freshwater pulmonates, one immunoreactive to leucine-enkephalin (LEnk-ir) and another to FMRFamide (FMRFa-ir). In addition, NADPH diaphorase (NADPHd)-positive elements apparently producing nitric oxide (NO) were demonstrated in t

Pearson syndrome (PS) is a multisystem disease including refractory anemia, vacuolization of marrow precursors and pancreatic fibrosis. The disease starts during infancy and affects various tissues and organs, and most affected children die before the age of 3years. Pearson syndrome is caused by de novo large-scale deletions or, more rarely, duplications in the mitochondrial genome. In the present

Mitochondrial DNA defects were known to be associated with a wide spectrum of human diseases and patients might present a wide range of clinical features in various combinations. In the current study, we described a patient with psychomotor and neurodevelopmental delay, mild hyperintensity of posterior periventicular white matter, generalized clonic seizures, leukodystrophy, and congenital deafnes

Silicon photomultipliers (SiPMs) are an enabling solid-state technology for low light sensing, with single photon sensitivity and photon number resolving capability. They feature an extremely high internal gain at the 106 level, comparable to photomultiplier tubes (PMTs), with the advantage of low operating voltage (~50 V compared to ~1000 V for PMT) and low energy consumption. The solid-state tec

One mechanism of resistance of prostate cancer (PCa) to enzalutamide (MDV3100) treatment is the increased expression of AR variants lacking the ligand binding-domain, the best characterized of which is AR-V7. We have previously reported that Phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), is a lipid kinase that links to CDK1 and AR pathways. The discovery of PIP5Kα inhibitor highlight th

Mortgage markets in developing economies, both past and present, are often confined to social networks between private individuals. The inadequate registration of ownership of and encumbrances on borrowers' real estate has been offered as a reason for this, but it is questionable whether such registration provides either a simple or a complete explanation. This paper analyses mortgage markets betw

It is unknown whether patients as a consequence of prosthetic joint replacement are at a higher risk of developing cancer. We therefore analyzed cancer incidence following prosthetic knee replacement (TKR). The observed cancer incidence in 14,551 patients from the population-based Swedish Knee Arthroplasty Register who have undergone TKR because of osteoarthrosis (OA, n = 10,120) or rheumatoid art

A research-based understanding of permafrost distribution at a sufficient spatial resolution is important to meet the demands of science, education and society. We present a new permafrost map for Norway, Sweden and Finland that provides a more detailed and updated description of permafrost distribution in this area than previously available. We implemented the CryoGRID1 model at 1km2 resolution,

Nocturnal dung beetles (Scarabaeus satyrus) are currently the only animals that have been demonstrated to use the Milky Way for reliable orientation. In this study, we tested the capacity of S. satyrus to orient under a range of artificial celestial cues, and compared the properties of these cues with images of the Milky Way simulated for a beetle’s visual system. We find that the mechanism that p

Night vision is ultimately about extracting information from a noisy visual input. Several species of nocturnal insects exhibit complex visually guided behaviour in conditions where most animals are practically blind. The compound eyes of nocturnal insects produce strong responses to single photons and process them into meaningful neural signals, which are amplified by specialized neuroanatomical

AZD5423 is a selective glucocorticosteroid receptor modulator developed for the inhaled use in asthma and COPD. This study reports the initial, first-in-man, single and repeat dose-escalating studies in healthy male individuals, including one cohort of male Japanese individuals. Inhaled, nebulized AZD5423 was safe and well tolerated up to and including the highest doses tested for up to 2 weeks of