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Background: Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play essential roles in tumor invasion and metastasis. High levels of both uPA and PAT-1 are associated with poor prognosis in breast cancer patients. To confirm the prognostic value of uPA and PAI-1 in primary breast cancer, we reanalyzed individual patient data provided by members of the European Organization for Re

The mutual recognition between Israel and the PLO in 1993 signalled a major shift in the Israeli-Palestinian conflict. This study examines, both theoretically and empirically, the basic question of how meaning of conflict may change and how conflict may be resolved. The broad aims are: first, to analyse and empirically improve knowledge of the transitional processes from conflicting interaction to

Objective: To investigate the association of a posteriori dietary patterns with overall survival of older Europeans. Design and setting: This is a multi-centre cohort study. Cox regression analysis was used to investigate the association of the prevailing, a posteriori-derived, plant-based dietary pattern with all-cause mortality in a population of subjects who were 60 years or older at recruitmen

Both natural and synthetic polyelectrolytes form strong complexes with a variety of proteins. One peculiar phenomenon is that association can take place even when the protein and the polyelectrolyte carry the same charge. This has been interpreted as if the ion-dipole interaction can overcome the repulsive ion-ion interaction. On the basis of Monte Carlo simulations and perturbation theory, we pro

Abstract is not available

We show that for steady, periodic, and rotational gravity deep-water waves, a monotone surface profile between troughs and crests implies symmetry. It is observed that if the vorticity function has a bounded derivative, then it vanishes as one approaches great depths.

Popular Abstract in Swedish Kristna, speciellt de av icke-judisk ursprung, som under det första århundradet drog sig undan aktiv medverkan i de traditionella grekisk-romerska kulterna och som i grekisk-romersk kontext kom att identifieras som utövare av något annat än traditionell judendom hamnade snart i ett socio-politisk dilemma. Å ena sidan skapade de tidiga kristnas fria hållning till den judWhen first-century gentile Christians withdrew from the traditional and civic Graeco-Roman cults and increasingly began to be identified by the Romans as not belonging to mainstream or common Judaism, they soon found themselves pressed "between synagogue and state." On the one side, the fact that they did not observe the Torah elicited hostility from Jews who did not want to be identified with a m

The angular pattern of scattered X-ray radiation (1.2-2.5 Angstrom) from flames has been measured and analyzed. The results are compared with calculations on different molecules, such as polyaromatic hydrocarbons, fullerenes and other spherical structures. Measurements have also been performed on soot condensed on a cooling plate inserted inside a flame. Size- and shape-dependent structures are ob

Aims To compare the effect of initial monotherapy with either bisoprolot or enalapril, followed by their combination, on mortality and hospitalization in patients with mild-to-moderate CHF. Methods and results One thousand and ten patients with mild-to-moderate CHF and left ventricular ejection fraction <= 35%, without ACE-inhibitor, beta-blocker, or angiotensin-receptor-blocker therapy were rando

Det i Sverige dominerande perspektivet på etnokulturella frågor definierar invandrare och flyktingar i termer av ekonomiska problem och sociala motsättningar. Ansvaret för den systematiska begreppsförvirring och tilltagande kuturrasism som präglar det offentliga samtalet vilar tungt på ledande massmedier, politiker och s k invandrarforskare.

Skoklosters slott under 350 år, historia, arkitektur, konst.

The low-lying core-excited quintet states of Mg I have been studied experimentally and theoretically. On the basis of beam-foil spectroscopy, the energies of nearly all the quintet levels belonging to the 2p(5)3s3p2 and 2p(5)3s3p4s configurations have been established, while only 5F levels from the 2p(5)3s3p3d configuration could be identified. Multiconfigurational Hartree-Fock calculations, inclu

Reduction of the model platinum(IV) complexes cis-[PtCl4(NH3)(2)] (1), trans-[PtCl4(NH3)(2)] (2). trans-[PtCl2(en)(2)](2+) (3), trans-[PtBr2(NH3)(4)](2+) (4), [PtCl6](2-) (5), and [PtBr6](2-) (6) with L-ascorbic acid (H(2)Asc) in 1.0 M aqueous medium at 25 degreesC in the region 1.75 less than or equal to pH less than or equal to 7.20 has been investigated using stopped-flow spectrophotometry. The

OBJECTIVES: To evaluate effects of postmenopausal hormone replacement therapy (HRT) on von Willebrand factor, factor (F)VIII, factor (F)VII, fibrinogen, antithrombin (AT) III, prothrombin fragments 1 and 2, protein C, total and free protein S, plasminogen activator inhibitor-1 (PAI-1), tissue plasminogen activator (tPA) and resistance to activated protein C. DESIGN: Part 1: double blind randomized