Background: Epigenetic factors regulate tissue-specific expression and X-chromosome inactivation. Previous studies have identified epigenetic differences between sexes in some human tissues. However, it is unclear whether epigenetic modifications contribute to sex-specific differences in insulin secretion and metabolism. Here, we investigate the impact of sex on the genome-wide DNA methylation pat

Purpose - The purpose of this paper is to investigate how well grocery stores' motives to implement private labels (create margins and customer perceived brand value, compete with market leading brands, develop store image, enhance store loyalty) are realized, through exploring consumers' attitudes, preferences and behaviour. Design/methodology/approach - The paper is based on the case of Sweden a

Popular Abstract in Swedish Det finns två skäl till att Sverige lämpar sig särskilt väl för att studera tuberkulosepidemiologi: 1) den svenska tuberkulosepidemiologin har gått från en svår epidemi i slutet av 1800-talet, fullt i paritet med de värst drabbade länderna globalt idag, till den situation vi har idag nästan helt utan inhemsk smittspridning. 2) En allt större del av befolkningen som växtSweden provides a special setting for epidemiological and demographic studies of tuberculosis (TB) infection over time for principally two reasons; first, the Swedish TB epidemic has undergone a tremendous transition since the end of the 19th century, when TB was highly endemic, to the current situation with practically interrupted indigenous transmission since several decades. Second, an increasi

Vernacular architecture is suffering all over the world and Egypt is one of the countries where the desert vernacular is facing a great risk of disappearance. The aim of the research is to introduce a methodological approach applying participatory action research (PAR) as a tool to help save the future of the currently deteriorating desert vernacular architecture. The aim was to help prevent furth

Popular Abstract in Swedish Glas som konstruktionsmaterial är relativt nytt och har blivit mer utbrett på grund av tekniska framsteg inom produktion av planglas, för vidarebearbetning av det tillverkade glaset och utvecklingen inom datorbaserade analysmetoder som finita elementmetoden. Jämfört med andra konstruktionsmaterial, till exempel betong, är kunskapen om glasets mekaniska egenskaper och stIn this thesis, user friendly and efficient methods for the design of glass structures are developed. The glass structures comprise various boundary conditions. Several types of glass are considered: single layered glass as well as laminated and insulated glass units. Typical load cases for strength design of glass are applied. A recently developed finite element is suggested to be suitable for th

A ternary Mg2COH5 hydride was synthesized using a novel method that relies on a relatively short mechanical milling time (1 h) of a 2:1 MgH2-Co powder mixture followed by sintering at a sufficiently high hydrogen pressure (>85 bar) and heating from RT to 500 degrees C. The ternary hydride forms in less than 2.5 h (including the milling time) with a yield of similar to 90% at similar to 300 degrees

Smallholders in developing countries can potentially benefit from access to local, regional, national and international markets as they intermediate between rural and urban demand for agricultural products and smallholder supply. This study investigates how smallholders in Meru, Tanzania make use of the various marketing channels that are available to them, and argues that the variety of potential

A rapid method for the determination of the sum of free desmosine and isodesmosine in human plasma and urine is described. Efficient sample clean-up prior to LC-MS/MS analysis is mandatory for detection of free desmosines in plasma samples. The combination of ultra-filtration and a two-step solid phase extraction minimizes the sample complexity and ion suppression effects. The flow through from th

Background: The combination of the new high sensitivity troponin T (hsTnT) assays and copeptin, a biomarker of endogenous stress, has been suggested to have the potential of early rule-out of acute coronary syndrome (ACS). The aim of this study was to examine the ability of this combination to rule out ACS in patients presenting with chest pain and to compare the diagnostic performance to hsTnT al

Folkdans i Finland som scenisk framställning i slutet av 1800-talet.

Nocturnal hypoglycemia is a common and potentially very dangerous condition facing persons with insulin-treated diabetes. To reduce the risk of going low while sleeping, many patient wilfully elevate their glucose level before bedtime, thereby also eroding the conditions for a sound glucose control for the next day. Recent advances in sensor technology allow for real-time frequent monitoring of th

Integration of equipment in industrial robot cells is to an increasing part involved with interfacing modern Ethernet technologies and low-cost mass produced devices, such as vision systems, laser cameras, force-torque sensors, soft-PLCs, digital pens, pocket-PCs, etc. This scenario enables integrators to offer powerful and smarter solutions, more adapted to small and medium enterprises (SMEs), ca

Motivated by the recent discovery of a canyon of conductance suppression in a two-level equal-spin quantum dot system [Phys. Rev. Lett. 104, 186804 (2010)], the transport through this system is studied in detail. At low bias and low temperature a strong current suppression is found around the electron-hole symmetry point independent of the couplings, in agreement with previous results. By means of

Background: Cysteinyl leukotrienes (CysLTs) are potent pro-inflammatory mediators that are increased in samples from patients with inflammatory bowel diseases (IBDs). Individuals with IBDs have enhanced susceptibility to colon carcinogenesis. In colorectal cancer, the balance between the pro-mitogenic cysteinyl leukotriene 1 receptor (CysLT(1)R) and the differentiation-promoting cysteinyl leukotri

This article discusses the role of language skills, mainly with regard to foreign languages, in historical research. Three principal functions of language as a historical method are identified: 1) language skills as a tool for acquiring knowledge of the international state-of-the-art; 2) language skills as a tool for communicating research; and 3) language skills as a tool for interpreting histori

Training and communication are essential elements in the implementation of environmental management systems (EMS). This study is based on two main questions: (i) What methods for training and communication will support the implementation of EMS at a university? and, (ii) How did faculty and staff perceive the training and communication activities? The study includes a literature review, a case stu

Popular Abstract in Swedish Genom observationer och experiment kan man konstruera modeller för att beskriva otaliga fenomen och aspekter av det universum vi lever i. Den huvudsakliga ingrediensen i en dylik modell är ofta en partiell differentialekvation. Sådana ekvationer kan beskriva så vitt skilda fenomen som t.ex. hur galaxer bildas, hur luftflöden transporteras i atmosfären, hur kemikalier reThis thesis is based on five papers, which all analyse different aspects of splitting schemes when applied to nonlinear parabolic problems. These numerical methods are frequently used when a problem has a natural decomposition into two or more parts, as the computational cost may then be significantly decreased compared to other methods. There are two prominent themes in the thesis; the first con

OBJECTIVE:: To compare the effects of ST-waveform analysis in combination with cardiotocography with conventional cardiotocography for intrapartum fetal monitoring. DATA SOURCES:: We searched MEDLINE, Embase, and PubMed for randomized controlled trials (RCTs) evaluating ST-waveform analysis for intrapartum fetal monitoring. METHODS OF STUDY SELECTION:: We identified RCTs that compared ST-waveform