One of the issues of modern cities is their urban design which is not structured to allow human interaction and promote a feeling of community within their inhabitants. The constant growth and shortages of land are cause to the global housing crisis which requires densification. In the current capitalistic context, urban design becomes just another pawn of this profit making machine, causing gentr

Serious violent crimes have increased among children and adolescents in recent years in Sweden. This development has caused the Swedish government to press for increased collaboration and cooperation between social services and the police. This study aimed to take a closer look at how this current cooperation between social services and the police works, from the social services’ point of view. In

This study aims to examine the challenges and practices of staff working at accommodations regulated by the Swedish Act concerning support and service for persons with certain functional impairments (LSS) when working with women with disabilities who have suffered from violence. Previous research shows that women with disabilities are at a greater risk of being victims of violence. Despite this kn

The primary aim of this study has been to explore nonprofit actors’ experiences and understanding of educating children and youth about pornography and sexual violence. Furthermore, the study has explored how nonprofit actors respond to and approach children and youths’ pornography consumption and their exposure to sexual violence. Lastly, the study researched the challenges and possibilities the

This study aimed to identify which perpetrators appear in the culture of honor and how their roles are described in four women's depictions in their autobiographies. Furthermore, the aim was to understand the upholding of the culture of honor through their stories. The chosen method for this study was a qualitative thematic text analysis of four autobiographies. The theoretical framework for t

Introduction: Little is known regarding the comparison of cardiovascular and kidney outcomes between lupus nephritis (LN) and other etiologies of chronic kidney disease (CKD). Methods: Using data from the Swedish Renal Registry (2006–2021), we compared long-term outcomes between patients with LN-CKD and patients with CKD due to primary glomerular diseases (PGD) and other CKD causes (Other-CKD, mai

A glimpse into a better world: The 4th Symphony Concert C with the world-class trumpeter Håkan Hardenberger and Jörg Widmann, the principal guest conductor of the NDR Radio Philharmonic, is about nothing less.While the warlike tones in Felix Mendelssohn Bartholdy's "Scottish" symphony finally give way to a roaring hymn of joy, Jörg Widmann's "Towards Paradise" strives for a utopian state of limbo.

BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie

Syftet med artikel 102 FEUF är att förbjuda vissa konkurrensmetoder från att användas, av företag med en dominant ställning på sin relevanta marknad. Anledningen är att konkurrensen ensam inte alltid kan begränsa dominanta företags handlingsfrihet, vilket skapar utrymme för missbruk, till skada för både konkurrenter och konsumenter. Ett exempel på missbruk är rovprissättning, där ett företag The objective of article 102 TFEU is to prohibit certain methods of competition by undertakings with a dominant position in their relevant market. Reason being that competition alone cannot always limit a dominant undertaking’s ability to conduct freely, which creates an opportunity of abusive conduct that harms both competitors as well as consumers. One example of such abusive conduct is pre

The thesis focuses on the design of a laboratory setup for a 100 kW fuel cell system, intended for heavy-duty vehicle applications. The increasing interest in Proton Exchange Membrane (PEM) fuel cells as a viable alternative for long-haul transport stems from the limitations of battery-electric vehicles, particularly due to the weight and energy density constraints of current battery technologies.

This study investigates the thermal-hydraulic performance of a passive Reactor Cavity Cooling System (RCCS) designed for a 250 MW molten salt reactor. The analysis focuses on the feasibility of natural convection-driven cooling as a passive safety mechanism. Simulations were performed using MATLAB and validated with COMSOL to evaluate the system under varying pipe configurations, diameters, and ou

The FragMAX facility at MAX IV Laboratory is a state-of-the-art platform for crystallographic fragment screening, designed to support structure-based drug and chemical tool compound discovery. This facility offers a comprehensive workflow, from high-throughput crystal preparation and automated diffraction data collection at the BioMAX beamline to advanced data processing and analysis using custom

On-chip optical communication between individual nano optoelectronic components is important to reduce the footprint and improve energy efficiency of photonic neuromorphic solutions. Although nanoscale photon emitters and receivers have been reported separately, communication between them remains largely unexplored. We demonstrate direct on-chip directional broadcasting of light between individual

The molecular characteristics of the pseudoautosomal region (PAR) of sex chromosomes remain elusive. Despite significant genome-sequencing efforts, the PAR of highly differentiated avian sex chromosomes remains to be identified. Here we use linkage analysis together with whole-genome re-sequencing to uncover the 630-kb PAR of an ecological model species, the collared flycatcher. The PAR contains 2

BACKGROUND: The endosymbiotic relationship between Wolbachia bacteria and insects has been of interest for many years due to their diverse types of host reproductive phenotypic manipulation and potential role in the host's evolutionary history and population dynamics. Even though infection rates are high in Lepidoptera and specifically in butterflies, and reproductive manipulation is present in th

Planthoppers (Hemiptera: Fulgoromorpha) are a species-rich and globally distributed insect clade with high economic, ecological and evolutionary importance. However, the relationships among planthopper lineages and families remain unclear. Previous efforts based on inconsistent morphological traits, a few genes or limited sampling often resulted in conflicting tree topologies. Here, we used genome

The biology centered around the TGF-beta type I receptor Activin Receptor-Like Kinase (ALK)1 (encoded by ACVRL1) has been almost exclusively based on its reported endothelial expression pattern since its first functional characterization more than two decades ago. Here, in efforts to better define the therapeutic context in which to use ALK1 inhibitors, we uncover a population of tumor-associated

The APOE4 allele is the strongest genetic risk factor for sporadic Alzheimer's disease (AD). While APOE4 is strongly associated with amyloid-beta (Aβ), its relationship with tau accumulation is less understood. Studies evaluating the role of APOE4 on tau accumulation showed conflicting results, particularly regarding the independence of these associations from Aβ load. In this study, we examined t

OBJECTIVE: Systemic inflammatory autoimmune diseases (SIADs) such as systemic lupus erythematosus (SLE), primary Sjögren disease (pSS), and idiopathic inflammatory myopathies (myositis) are complex conditions characterized by shared circulating autoantibodies and clinical manifestations, including skin rashes, among others. This study was aimed at elucidating the genetics underlying these common f