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A prospective study of quality of life in head and neck cancer patients. Part I: at diagnosis

PURPOSE: A Swedish and Norwegian study was designed to examine health-related quality of life (HQL) in patients with head and neck cancer (head and neck) at diagnosis and during treatment and rehabilitation. The overall aim was to examine the impact on HQL at diagnosis depending on tumor location, stage, sex, and age (part I) and to describe HQL longitudinally and determine for which patients and

Screening of yeast species for the stereo-selective reduction of bicyclo[2.2.2]octane-2,6-dione

Yeast strains from more than 31 different genera were screened for the enantioselective reduction of bicyclo[2.2.2]-octane-2,6-dione (1). Reducing activity was found in 80% of the screened yeasts. Bicyclo[2.2.2]octane-2,6-dione was enantioselectively reduced (> 98% ee) to (1R, 4S, 6S)-6-hydroxybicyclo[2.2.2]octane-2-one (-)-2 by 69% of the strains. Enantioselective reduction of the diketone to (1S

No title

At the beginning of the 21st Century, Zen Buddhism is no longer an unknown religion in the West. Zen-meditation enjoys great popularity, the books regarding the subject are among the bestsellers and the auditoriums are crowed if the topic concerns the bringing home of Zen Buddhism to a Western audience. At the same time Zen Buddhism today is by no means merely the religion of Zen Buddhists, but pr

Human granulocytic ehrlichiosis as a common cause of tick-associated fever in Southeast Sweden: Report from a prospective clinical study

Between May and December 1998, tick-associated febrile illness was prospectively studied in Southeast Sweden in order to assess the occurrence of human granulocytic ehrlichiosis (HGE). Inclusion criteria were fever (greater than or equal to 38.0degreesC), with or without headache, myalgia or arthralgia in patients with an observed tick bite or tick exposure within 1 month prior to onset of symptom

Hypotermi efter perinatal asfyxi minskar risken för hjärnskada. Men för tidigt att rekommendera rutinmässig behandling

Måttlig hypotermi efter perinatal asfyxi reducerar mortaliteten och risken för överlevnad med svårt handikapp, visar två randomiserade, kontrollerade studier. Fler studier pågår och förväntas bli publicerade inom de närmaste åren. Den publicerade studien visar dock att det endast är barn med måttlig hjärnskada som har effekt av hypotermi. Hypotermi efter perinatal asfyxi kan ännu inte rekommenderaTwo randomised controlled trials evaluating intervention with moderate hypothermia after perinatal asphyxia will probably be published this year. The first study, evaluating head cooling with a "cool cap" is already published, and preliminary data from the other study evaluating body cooling earlier have been presented. Both studies indicate that moderate hypothermia, initiated within 6 h after bi

Perforations of the Upper Gastro-Intestinal Tract

Material and methods: In all, 237 consecutive patients with a perforated peptic ulcer admitted from 1974-1992 and 125 consecutive patients with an oesophageal perforation admitted from 1970-2006 to Lund University hospital were studied retrospectively. Prognostic factors were evaluated using the Cox proportional hazards model. All cases of gastro-duodenal ulcer perforations diagnosed in Sweden fr

Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: Results of the CABG surgery cohort of the GUARDIAN study

Objectives: To evaluate the effects of cariporide on all-cause mortality or myocardial infarction at 36 days in patients at risk,of myocardial necrosis after coronary artery bypass graft surgery. Methods: In the coronary artery bypass graft cohort of the GUARD During Ischemia Against Necrosis trial, patients greater than or equal to 18 years who required urgent coronary artery bypass graft, repeat

Impacts of Regional Climate Change on Swedish Forests: An Evaluation Using Process-based Regional Ecosystem Modelling Approach

The overall aim of this thesis was to provide a representative estimate of the potential impacts of climate change and increased atmospheric CO2 concentrations on Swedish forest ecosystems and the key ecosystem services they provide. In order to achieve this task, fi rst LPJ-GUESS, a process-based regional ecosystem modelling framework, was applied to explore how possible shifts in climatic zones

Study and Development of Techniques to Improve Engine Stability and Reduce Emissions from Natural Gas Engines

Popular Abstract in Swedish Denna avhandling beskriver olika metoder att förbättra motorstabilitet och minska skadliga avgasutsläpp från naturgasmotorer. Gasflöden inuti cylindern mättes med laserdiagnostik, även cylindertryck och avgassammansättning mättes. Sex olika förbränningsrum utvärderades med ovan angivna metoder. Ett högturbulent (brinner snabbt) förbränningsrum visade sig fungera bäst meThe objective of this thesis was to find ways to improve combustion and reduce emissions from supercharged natural gas engines. In-cylinder flow measurements were made with laser doppler velocimetry, LDV, heat release was calculated from cylinder pressures and emissions were measured at various locations. The original combustion chamber was a low turbulence-generating geometry, resulting in an ove

Radiological changes in asbestos cement workers

OBJECTIVE--To explore associations between exposure to asbestos cement dust and radiographic findings in lung parenchyma and pleura. METHODS--Radiographs from 174 blue collar workers and 29 white collar workers from an asbestos cement plant formed one part of the study. Progression of small opacities was further studied in those 124 blue collar workers, for whom two radiographs taken after the end

Food and secretagogue stimulation decrease the digestive enzyme content remaining in the rat pancreas

The aim of the study reported here was to investigate changes in the digestive enzyme content in the pancreas after food and secretagogue stimulation. Rats from which food had been withheld overnight were either fed (between 6 and 8 a.m.) or not before euthanasia and pancreatic excision (at 8 a.m.: 21 not fed and 21 fed) and at 4 (12 p.m.: six not fed and six fed) and 8 h later (4 p.m.: six not fe

The genus Pilosella in the Nordic countries

An unprejudiced revision of the genus Pilosella (Asteraceae) in the Nordic countries has been attempted. A completely new system for the taxonomy of these mostly facultative apomicts is presented. It is argued that all existing systems are inappropriate in the light of the complicated, and largely unknown, reproductive biology of these taxa. Previous systems have either treated these taxa as oblig

Young women with genital prolapse have a low collagen concentration

Background. Genital prolapse is a common and handicapping form of pelvic floor dysfunction. To explain its genesis as a result of endopelvic connective tissue weakness, the collagen state was analyzed in women with and without genital prolapse. Methods. Punch biopsies from the paraurethral ligaments were obtained during the operation from 22 women undergoing surgery for genital prolapse. As contro

Bioavailability of selenium from bovine milk as assessed in subjects with ileostomy

Objective: To assess the absorption of dietary selenium in humans, especially of milk selenium. Design: 1-day meal studies in subjects with ileostomy. Setting: Hospital outpatient clinics. Subjects: Three subjects in the pilot study and nine subjects in the main study ( eight men/four women). Intervention: Different beverages, 1 l/day, were given in addition to basal diets ( soft drink, 1 week; lo

External Stakeholder Analysis in Construction Project Management

The planning and construction of a facility can affect several interests. Positive effects are, for instance, better communications, better housing and a higher standard of living. However, construction projects inevitably bring varying degrees of deterioration and change at the local level, not least at the construction site. Representatives of these interests are referred to as the project's sta

Macrophages in inflammatory bowel disease

Blood monocytes which differentiate into tissue macrophages, are unique in that they can not only initiate immune responses but can also be effector cells which contribute to the resolution of these responses. There is no single activation phenotype, and macrophages can be induced to differentiate into cells that either exacerbate or inhibit acute inflammation. Similarly, these cells can promote,