By mimicking embryonic development of the hematopoietic system, we have developed an optimized in vitro differentiation protocol for the generation of precursors of hematopoietic lineages and primitive hematopoietic cells from human embryonic stem cells (ES) and induced pluripotent stem cells (iPS). Factors such as cytokines, extra cellular matrix components, and small molecules, as well as the te

The title compound, cis-[Pt(CH3COO)2(C2H6S)2], crystallizes in the P21/c space group with a pseudo-square-planar geometry. The complex forms centrosymmetric dimeric packing units, with C-H...O-Pt interactions and a short Pt...Pt distance [3.5868(2) Å]. The coordination mode of the acetate ligands is monodentate and they are oriented almost perpendicular to the coordination plane. Cambridge Structu

Consider the communication system model y = HFx+n, where H and F are the channel and precoder matrices, x is a vector of data symbols drawn from some lattice-type constellation, such as M-QAM, n is an additive white Gaussian noise vector and y is the received vector. It is assumed that both the transmitter and the receiver have perfect knowledge of the channel matrix H and that the transmitted sig

Using the information of the microstructure, this paper presents the development of an incremental constitutive law governing the response of an electro-magneto-thermo-mechanical smart composite. In this development, different shapes of reinforcements that have magneto-electro-thermo-elastic properties that differ from the matrix material are considered. Shapes such as ellipsoidal (spherical, prol

Här jämförs författaren Axel Wallengren (Falstaff, fakir) med några kvinnliga skribenter: Anna Myrberg (Svarta Masken), Klara Johanson, Harriet Löwenhjelm och Astrid Lindgren. Stilistisk släktskap och personliga beröringspunkter ger nya perspektiv på Wallengrens särdrag.

We investigate various mechanisms contributing to the surface ion distributions in simple and mixed aqueous alkali-halide solutions depending on the total salt concentration, using a combination of photoelectron spectroscopy and molecular dynamics simulations. In simple solutions, the surface enhancement of large polarizable anions is reduced with increasing concentration. In the case of a NaBr/Na

Background: The intake of dietary fibre has been shown to reduce the risk of developing diabetes mellitus. The aim of this study was to compare the effects of commercial rye whole-meal bread containing whole kernels and white wheat bread on the rate of gastric emptying and postprandial glucose response in healthy subjects. Methods: Ten healthy subjects took part in a blinded crossover trial. Blood

Background: The thermostable beta-glucosidase (TnBgl1A) from Thermotoga neapolitana is a promising biocatalyst for hydrolysis of glucosylated flavonoids and can be coupled to extraction methods using pressurized hot water. Hydrolysis has however been shown to be dependent on the position of the glucosylation on the flavonoid, and e. g. quercetin-3-glucoside (Q3) was hydrolysed slowly. A set of mut

The effect of glucose and oxygen limitation on the growth and fermentation performances of Dekkera bruxellensis was investigated in order to understand which factors favour its propagation in ethanol or wine plants. Although D. bruxellensis has been described as a facultative anaerobe, no growth was observed in mineral medium under complete anaerobiosis while growth was retarded under severe oxyge

The loss of native riparian vegetation and its replacement with non-native species or grazing land for agriculture is a worldwide phenomenon, but one that is prevalent in Europe, reflecting the heavily-modified nature of the continent's landscape. The consequences of these riparian alterations for freshwater ecosystems remain largely unknown, largely because bioassessment has traditionally focused

In this paper, we develop superfast approximative algorithms for the computationally efficient implementation of the recent Iterative Adaptive Approach (IAA) spectral estimate. The proposed methods are based on rewriting the IAA algorithm using suitable Gohberg-Semencul representations, solving the resulting linear systems of equations using the preconditioned conjugate gradient method, where a no

We present two novel culling tests for rasterization of simultaneous depth of field and motion blur. These tests efficiently reduce the set of xyuvt samples that need to be coverage tested within a screen space tile. The first test finds linear bounds in ut - and vt -space using a separating line algorithm. We also derive a hyperplane in xyuvt - space for each triangle edge, and all samples outside

Many spatial patterns in biology arise through differentiation of selected cells within a tissue, which is regulated by a genetic network. This is specified by its structure, parameterisation and the noise on its components and reactions. The latter, in particular, is not well examined because it is rather difficult to trace. The authors use suitable local mathematical measures based on the Vorono

Embodied pedagogical agents – visually represented, computer generated characters in pedagogical roles, such as virtual instructors, mentors and learning companions – populate the digital society in increasing numbers. They are found in educational programmes from preschool to university, as well as in broader educational contexts in the form of medical counsellors, virtual health coaches, informa

Dementia is a clinical syndrome with the development of impairment in multiple cognitive functions (including memory), severe enough to interfere with activities of daily living, as the main symptom. There are a large number of disorders that can lead to dementia, and neuropathological examination after death is necessary to determine the underlying cause with certainty. The overall aim of this th

We present time-resolved femtosecond photoelectron momentum images and angular distributions of dissociating, laser-aligned 1,4-dibromobenzene (C6H4Br2) molecules measured in a near-infrared pump, soft-x-ray probe experiment performed at an x-ray free-electron laser. The observed alignment dependence of the bromine 2p photoelectron angular distributions is compared to density functional theory cal

Cast in-situ concrete is the most frequently used materials technology worldwide within production of structural frames in multi-storey residential buildings. In Sweden, this technology dominates the market but is challenged by other competitive production methods. The criticism concerns issues as for instance short slab spans (limited flexibility for future refurbishment), long production times,

This doctoral thesis explores the implications of establishing tradable certificate schemes for improving energy efficiency (so-called ‘Tradable White Certificate’ [TWC] schemes). Carrying out different case studies, a set of complementary evaluation methods is applied in conducting ex-ante and ex-post evaluation studies. To analyse the attributes and complexities of TWC schemes, the thesis focuse