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Equalisation of alcohol participation among socioeconomic groups over time: an analysis based on the total differential approach and longitudinal data from Sweden

Background: Health inequality and its social determinants are well-studied, but the determinants of inequality of alcohol consumption are less well-investigated. Methods: The total differential approach of decomposition of changes in the concentration index of the probability of participation in alcohol consumption was applied to 8-year longitudinal data for Swedish women aged 28-76 in 1988/89. Re

Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients

Chronic myeloid leukemia (CML) stem cells appear resistant to tyrosine kinase inhibitors (TKIs) in vitro, but their impact and drug sensitivity in vivo has not been systematically assessed. We prospectively analyzed the proportion of Philadelphia chromosome-positive leukemic stem cells (LSCs, Ph+CD34+CD38=) and progenitor cells (LPCs, Ph+CD34+CD38+) from 46 newly diagnosed CML patients both at the

Achieving solar energy in architecture - IEA SHC Task 41

Despite the wide diversity of available solar technologies, solar energy systems are still not considered as main stream technologies in building practice. This may be attributed to several factors such as lack of awareness and knowledge among architects, lack of tools supporting the design process, and lack of solar products designed for building integration. In order to address these issues, the

Moisture fixation and thermal properties of lime–hemp concrete

Lime–hemp concrete (LHC) is a sustainable building material that combines hemp shiv and building limes. Moisture fixation and thermal properties of LHC were determined so as to gain knowledge about the material’s behaviour in a cold, wet climate. Sorption isotherms were produced over the whole moisture range for two LHC mixes by means of glass jar tests and a pressure plate apparatus. Thermal prop

Succinic acid in aqueous solution: connecting microscopic surface composition and macroscopic surface tension

The water vapor interface of aqueous solutions of succinic acid, where pH values and bulk concentrations were varied, has been studied using surface sensitive X-ray photoelectron spectroscopy (XPS) and molecular dynamics (MD) simulations. It was found that succinic acid has a considerably higher propensity to reside in the aqueous surface region than its deprotonated form, which is effectively dep

Global Standard Stratotype-Section and Point (GSSP) for the Base of the Jiangshanian Stage (Cambrian: Furongian) at Duibian, Jiangshan, Zhejiang, Southeast China

The International Commission on Stratigraphy and the IUGS Executive Committee have recently approved a Global Standard Stratotype-section and Point (GSSP) defining the base of the second stage of the Furongian Series, Cambrian System. This stage is named the Jiangshanian Stage, after Jiangshan City, western Zhejiang Province, China, where the GSSP is located. The GSSP is exposed in a natural outcr

Degradation effects in the extraction of antioxidants from birch bark using water at elevated temperature and pressure

Experiments with birch bark samples have been carried to enable a distinction between extraction and degradation effects during pressurised hot water extraction. Two samples, E80 and El 80, contained birch bark extracts obtained after extraction at 80 and 180 degrees C for up to 45 min, respectively. Two other samples, P80 and P180, were only extracted for 5 min at the two temperatures and were th

To jointly negotiate a personal decision: a qualitative study on information literacy practices in midwifery counselling about contraceptives at youth centres in Southern Sweden

Introduction. The study is part of a project in which young women’s evaluation of information sources before choosing a contraceptive is studied. It focuses on young women meeting midwives for counselling about contraceptives. Conversations are information literacy practices with both parties negotiating about needed and appropriate information on which they will base decisions. Method. Ten conve

The heart in the critically ill patient- an echocardiographic study

The thesis describes aspects of left ventricular systolic and diastolic function examined with echocardiography in patients with systemic inflammation and shock. Background: Myocardial depression is a well-known complication in critically ill patients with shock. Echocardiography is increasingly used for assessing left ventricular (LV) function in these patients. Aims: 1) To describe the feasibili

Copy number variants in the kallikrein gene cluster.

The kallikrein gene family (KLK1-KLK15) is the largest contiguous group of protease genes within the human genome and is associated with both risk and outcome of cancer and other diseases. We searched for copy number variants in all KLK genes using quantitative PCR analysis and analysis of inheritance patterns of single nucleotide polymorphisms. Two deletions were identified: one 2235-bp deletion

Photobleaching-Insensitive Fluorescence Diagnostics in Skin and Brain Tissue

In this paper, we investigate the possibility of using accurate prediction models for the prediction of protoporphyrin bleaching dynamics to achieve photobleaching-insensitive methods to improve the evaluation of data in an existing clinical fluorescence-guided resection technique. To simulate the scenario, measurements were carried out in vivo on skin of healthy volunteers using a compact fiber-b

Modelling Tundra Vegetation Response to Recent Arctic Warming

The Arctic land area has warmed by > 1 A degrees C in the last 30 years and there is evidence that this has led to increased productivity and stature of tundra vegetation and reduced albedo, effecting a positive (amplifying) feedback to climate warming. We applied an individual-based dynamic vegetation model over the Arctic forced by observed climate and atmospheric CO2 for 1980-2006. Averaged ove

The mechanism of HAMLET-induced cell death - cellular signalling, oncogenes and clinical perspectives

Popular Abstract in Undetermined 1971 förklarade president Richard Nixon, som så många amerikanska presidenter före honom, krig. Nixons fiende var dock något oortodox; Nixon förklarade krig mot cancer. I och med att senaten godkände ”National Cancer Act”, av pressen snabbt döpt till ”War on cancer”, hoppades Nixon att kunna utradera cancer med hjälp av kraftigt ökade anslag till cancerforskning koDespite recent advances in cancer treatment, truly innovative approaches are required to move beyond the modest benefits achieved to date. HAMLET is a human protein-lipid complex originally discovered in breast milk able to kill a wide range of tumour cells while leaving healthy, differentiated cells unaffected. The aim of this thesis was to identify mechanisms dictating HAMLET sensitivity and to

Family caregivers' subjective experiences of satisfaction in dementia care: aspects of burden, subjective health and sense of coherence.

Family caregivers experience both positive and negative reactions in caregiving situations. There has been considerably less published about the positive aspects, however. The general aim of this study was to explore a previously developed instrument to study rewards gained by caregivers and to determine the factors associated with satisfaction in family members caring for patients with dementia l

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Abstract in French Le but de l’étude présente est de démontrer que la distinction entre le langage plastique et le langage iconique, introduite par Floch et Groupe µ, reste utile, à condition de la faire subir une série de modifications : d’abord, il ne faut pas parler du langage iconique, mais du langage pictural, parce que l’iconicité peut très se retrouver aussi bien du côté plastique. Ensuite,The task of the present study is to establish the useful of the distinction between plastic language and iconic language, as introduced by Floch and the Groupe µ, with the proviso that it has to be changed in a number of ways. To begin with, we should not talk about iconic language, but rather about a pictorial one, because iconicity is a much broader concept, and just as probably may found on the