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Imaging of sugar-based contrast agents using their hydroxyl proton exchange properties

The ability of CEST MRI to detect the presence of millimolar concentrations of non-metallic contrast agents has made it possible to study, noninvasively, important biological molecules such as proteins and sugars, as well as drugs already approved for clinical use. Here, we review efforts to use sugar and sugar polymers as exogenous contrast agents, which is possible based on the exchange of their

Teacher Subject Knowledge, Didactic Skills, and Student Learning in Francophone Sub-Saharan Africa

We study the effects of two dimensions of teacher quality, subject knowledge and didactic skills, on student learning in francophone Sub-Saharan Africa. We use data from an international large- scale assessment in 14 countries that include individual-level information on student achievement and country-level measures of teacher subject knowledge and didactic skills in reading and math. Exploiting We study the effects of two dimensions of teacher quality, subject knowledge and didactic skills, on student learning in francophone Sub-Saharan Africa. We use data from an international large- scale assessment in 14 countries that include individual-level information on student achievement and country-level measures of teacher subject knowledge and didactic skills in reading and math. Exploiting

Energy transfer in multi-funnel systems quantitatively assessed by two-dimensional polarization imaging and single funnel approximation : From single molecules to ensembles

Two-dimensional polarization imaging (2D POLIM) is an experimental method where correlations between fluorescence excitation- and fluorescence emission-polarization properties are measured. One way to analyze 2D POLIM data is to apply a so-called single funnel approximation (SFA). The SFA allows for quantitative assessment of energy transfer between chromophores with identical spectra [homo-FRET (

Achromatic Cues Are Important for Flower Visibility to Hawkmoths and Other Insects

Studies on animal colour vision typically focus on the chromatic aspect of colour, which is related to the spectral distribution, and disregard the achromatic aspect, which is related to the intensity (“brightness”) of a stimulus. Although the chromatic component of vision is often most reliable for object recognition because it is fairly context independent, the achromatic component may provide a

Medborgerligt engagemang på sociala medier

Vi lever i en tid som präglas av sociala mediers växande betydelse inom en lång rad områden, inte minst när det gäller medborgerligt engagemang. I detta kapitel skissar vi en översiktsbild av olika sätt att tänka kring sociala medier och medborgerligt engagemang, och ger också en kort inblick i vad medborgarundersökningen berättar om engagemang på sociala medier. Medborgerligt engagemang i sociala

Combining semilocal exchange with dynamical mean-field theory : Electronic structure and optical response of rare-earth sesquioxides

In rare-earth semiconductors, wide ligand p and rare-earth 5d bands coexist with localized, partially filled 4f shells. A simultaneous description for both extended and localized states represents a significant challenge for first-principles theories. Here, we combine an ab initio dynamical mean-field theory approach to strong local correlations with a perturbative application of the semilocal mod

Design of a high-resolution Rayleigh-Taylor experiment with the Crystal Backlighter Imager on the National Ignition Facility

The Rayleigh-Taylor (RT) instability affects a vast range of High Energy Density (HED) length scales, spanning from supernova explosions (1013 m) to inertial confinement fusion (10-6 m). In inertial confinement fusion, the RT instability is known to induce mixing or turbulent transition, which in turn cools the hot spot and hinders ignition. The fine-scale features of the RT instability, which are

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Phalangeal fractures are common in all ages. Stable, extraarticular fractures can be treated non-operatively by closed reduction and buddy taping, while surgical fixation should be considered for unstable and displaced extra-articular fractures and most intra-articular fractures. The treatment should aim at early, active mobilisation in order to achieve the optimal functional outcome. Since intra-

Stem cell aging and wound healing

Aging is a natural process that promotes different pathologies and progressive functional losses of cells and tissues. Aging impacts stem cell reserve and function negatively, resulting in compromising tissue regeneration. Stem cell aging significantly impairs wound healing properties of different tissues due to the age-related aberrant changes like increased proinflammatory cytokines, accumulatio

Potential for identification of wild night-flying moths by remote infrared microscopy

There are hundreds of thousands of moth species with crucial ecological roles that are often obscured by their nocturnal lifestyles. The pigmentation and appearance of moths are dominated by cryptic diffuse shades of brown. In this study, 82 specimens representing 26 moth species were analysed using infrared polarimetric hyperspectral imaging in the range of 0.95–2.5 µm. Contrary to previous studi

The Street of Associations : Migration and Infrastructural (Re)Production of Norra Grängesbergsgatan, Malmö

As global migration alters the demography of Swedish cities in the postwelfare era, socio-spatial polarisation and discrimination present acute challenges. In recent decades, Malmö has transformed from an industrial into a postindustrial, service economy-oriented city. The neoliberal urban planning and regeneration policies guiding such processes carry detrimental social and economic effects for u

Role of CRISPR/Cas9 and other gene editing/engineering technology in intestine diseases

A tremendous effort has been made over decades to develop technology to edit the genome. Genomes are composed of billions of DNA bases and contain all of the genetic information from organisms. The possibility to change DNA bases at precise sites sheds light on many perspectives, not only molecular biology but also applications in medicine and agriculture. Genome editing tools have come to the rev

The Art of Resistance in Islam : The Performance of Politics among Shi'i Women in the Middle East and Beyond

Based on first-hand ethnographic insights into Shi‘i religious groups in the Middle East and Europe, this book examines women’s resistance to state as well as communal and gender power structures. It offers a new transnational approach to understanding gender agency within contemporary Islamic movements expressed through language, ritual practices, dramatic performances, posters, and banners. By l

Diffusion MRI of Brain Tissue: Importance of Axonal Trajectory

Obtaining microstructural information non-invasively on brain tissue remains a challenge. Diffusion magnetic resonance imaging (dMRI) is an imaging method that can provide such information. That includes geometrical considerations of nerve cells projections, axons, that are present in the white matter of the human brain. Axons carry information encoded into electrical impulses to other cells.The t