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A Socio-technical toolbox for business systems analysis and design

This paper provides an overview of a socio-technical toolbox (STT) based on a combination of methods from a number of contemporary socio-technical (ST) methodologies. The STT supports a pragmatic ST approach to organizational change practice and job redesign. It has been developed and used in practice in many different types of organizations over a period of many years. The use in practice of STT

A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2

OBJECTIVE - Insulinoma-associated protein 2 (IA-2) is a major autoantigen in type I diabetes, and IA-2 autoantibodies are routinely detected by a liquid-phase radioimmunoprecipitation assay. The present experiments were initiated to develop a new assay that does not require the use of radioisotopes or autoantigens prepared in bacteria or by in vitro transcription/translation. RESEARCH DESIGN AND M

Monte Carlo Study of the Formation and Conformational Properties of Dimers of Aβ42 Variants.

Small soluble oligomers, as well as dimers in particular, of the amyloid β-peptide (Aβ) are believed to play an important pathological role in Alzheimer's disease. Here, we investigate the spontaneous dimerization of Aβ42, with 42 residues, by implicit solvent all-atom Monte Carlo simulations, for the wild-type peptide and the mutants F20E, E22G and E22G/I31E. The observed dimers of these variants

Characterisation and mitigation of beam-induced backgrounds observed in the ATLAS detector during the 2011 proton-proton run

This paper presents a summary of beam-induced backgrounds observed in the ATLAS detector and discusses methods to tag and remove background contaminated events in data. Trigger-rate based monitoring of beam-related backgrounds is presented. The correlations of backgrounds with machine conditions, such as residual pressure in the beam-pipe, are discussed. Results from dedicated beam-background simu

Infections as a stimulus for coronary occlusion, obstruction, or acute coronary syndromes.

BACKGROUND: : Atherosclerosis is considered to be an inflammatory disease. Infections are a significant cause of inflammation. Acute infections might precipitate acute coronary syndromes (ACS) whereas chronic infections might be stimuli for the development of atherosclerosis. METHODS: : Coronary angiograms were done on 211 of 335 patients with ACS and the percentage of coronary obstruction was det

J/psi suppression at forward rapidity in Au plus Au collisions at root s(NN)=200 GeV

Heavy quarkonia are observed to be suppressed in relativistic heavy-ion collisions relative to their production in p + p collisions scaled by the number of binary collisions. In order to determine if this suppression is related to color screening of these states in the produced medium, one needs to account for other nuclear modifications including those in cold nuclear matter. In this paper, we pr

Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells.

Critical functions of the immune system are maintained by the ability of myeloid progenitors to differentiate and mature into macrophages. We hypothesized that the cytoprotective gas molecule carbon monoxide (CO), generated endogenously by heme oxygenases (HO), promotes differentiation of progenitors into functional macrophages. Deletion of HO-1, specifically in the myeloid lineage (Lyz-Cre:Hmox1(

Thermally driven ballistic rectifier

The response of electric devices to an applied thermal gradient has, so far, been studied almost exclusively in two-terminal devices. Here we present measurements of the response to a thermal bias of a four-terminal, quasiballistic junction with a central scattering site. We find a novel transverse thermovoltage measured across isothermal contacts. Using a multiterminal scattering model extended t

Investigation of a prototype industrial gas turbine combustor using alternative gaseous fuels

Popular Abstract in Swedish Jordens totala energiförbrukning stiger. Samtidigt förbrukas primärt fossila naturresurser som kan anses ändliga, så som olja, kol eller naturgas, för att tillgodose energibehovet. Även andra energikällor används, t.ex. kärnbränsle, vind och vatten. Denna avhandling fokuserar på energi som omvandlas vid förbränning av gas i gasturbiner. Eftersom naturgas är ett fossilt In this thesis, the effect of alternative gaseous fuels, with high hydrogen content and lower calorific value, on gas turbine combustion was investigated experimentally. The aim of the investigation was to find operational limitations for an experimental burner and to supply data for validation of computational fluid dynamics (CFD). Before examination of the actual burner, the laminar flame speed

Food chain transport of nanoparticles affects behaviour and fat metabolism in fish.

Nano-sized (10(-9)-10(-7) m) particles offer many technical and biomedical advances over the bulk material. The use of nanoparticles in cosmetics, detergents, food and other commercial products is rapidly increasing despite little knowledge of their effect on organism metabolism. We show here that commercially manufactured polystyrene nanoparticles, transported through an aquatic food chain from a

A heuristic description of high-p(T) hadron production in heavy ion collisions

Using a simplified model for in-medium dipole evolution accounting for color filtering effects we study the production of hadrons at large transverse momenta p(T) in heavy ion collisions. In the framework of this model, several important sources of the nuclear suppression observed recently at RHIC and LHC have been analyzed. A short production length of the leading hadron l(p) causes a strong onse

Heart failure exacerbation leading to hospital admission: a cross-sectional study

Objectives The aim of this pilot study was to investigate cause(s) of heart failure (HF). Setting The emergency department and medical wards at Malmo University Hospital. Method A cross sectional pilot study. Main outcome measures Comparison of compliance, comprehension and optimal treatment on a population basis between men and women, younger (a parts per thousand currency sign75 years) and elder

Sulphur-Tolerant Catalysts In Small-Scale Hydrogen Production, A Review

The role of sulphur in the production of hydrogen in the small-scale for fuel cell applications is an important topic in the design of such systems and this review of the literature state-of-the-art has been performed to shed light on some of the possible trade-offs that will have to be done in designing these systems. The review-paper summarises the literature with respect to sulphur-laden cataly