A proportion of patients with severe asthma (SA) show poor responses to traditional asthma medications; however, it remains unknown why some patients remain persistently symptomatic. Our objective was to explore the use of laser-capture microdissection of specific epithelial structures combined with quantitative data-independent acquisition mass spectrometry to elucidate differences in protein com

The family Apidae, which is amongst the largest bee families, are important pollinators globally and have been well studied for their visual adaptations and visually guided behaviors. This review is a synthesis of what is known about their eyes and visual capabilities. There are many species-specific differences, however, the relationship between body size, eye size, resolution, and sensitivity sh

Aims: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known. Methods: Information on usual walking pace (self-defined as slow, steady/average, or brisk), dynamometer-assessed handgrip strength, lifestyle behaviours (physical activity, TV viewing, diet, alcohol intake,

The blood-brain barrier (BBB) is formed by the endothelial cells lining cerebral microvessels, but how blood-borne signaling molecules influence permeability is incompletely understood. We here examined how the apolipoprotein M (apoM)-bound sphingosine 1-phosphate (S1P) signaling pathway affects the BBB in different categories of cerebral microvessels using ApoM deficient mice (Apom-/-). We used t

What is the relationship between identity, representation and memory in contemporary performance practices? Does memory function as a basic tool in artist’s work or can it also be regarded as a hindrance?In current performance art, identity is often defined as an accumulation of one’s embodied experience and memory. The artist’s body can be seen as an archive which is re-enacted in the encounter w

The study of growth in African economies during the 20th Century is hampered by the lack of historical GDP estimates. There has been some backward projections, and country case studies, but despite the available data historical national accounts has not yet been assembled. This paper provides GDP estimates for some former British colonies between 1900 – 1950. The estimates indicate faster growth a

Iron N-heterocyclic carbene (NHC) complexes have received a great deal of attention recently because of their growing potential as light sensitizers or photocatalysts. We present a sub-ps X-ray spectroscopy study of an FeIINHC complex that identifies and quantifies the states involved in the deactivation cascade after light absorption. Excited molecules relax back to the ground state along two pat

The purpose of this report is to discuss how a decarbonising the steel, plastic, and paper industries may affect economic growth, wages and employment in the European Union (EU). We approach the issue from two different angles. First, we discuss how a decarbonization of the three industries may affect the rest of the economy. Second, we discuss how a decarbonization of the three industries may aff

Motion is a major confound in diffusion-weighted imaging (DWI) in the body, and it is a common cause of image artefacts. The effects are particularly severe in cardiac applications, due to the nonrigid cyclical deformation of the myocardium. Spin echo-based DWI commonly employs gradient moment-nulling techniques to desensitise the acquisition to velocity and acceleration, ie, nulling gradient mome

Insect pest management is a very important aspect for plant protection in crops production. Remote sensing provides a large number of techniques that are beneficial in entomological research. Although entomological radars have been used for studying migrations of insects for many years, most of entomological radar studies have been vertically tracing high-altitude migration behaviour of insects. L

Objectives: To describe logarithm of the minimum angle of resolution (logMAR) best corrected visual acuity (BCVA) and intraocular pressure (IOP) after surgical management of late in-the-bag dislocation of the intraocular lens. Subjects/methods: In a single-centre prospective study, 165 consecutive cases having surgical correction for late in-the-bag-dislocation of intraocular lenses were analysed.

Treatment of haemophilia A/B patients comprises factor VIII (FVIII) or factor IX (FIX) concentrate replacement therapy, respectively. FVIII and FIX activity levels can be measured in clinical laboratories using one-stage activated partial thromboplastin time (aPTT)-based clotting or two-stage chromogenic factor activity assays. We discuss strengths and limitations of these assays, providing exampl

Purpose: Postoperative bleeding after thyroid surgery remains a potentially lethal complication. Outpatient thyroidectomy is an increasing trend in the high volume centers. There is a need to identify risk factors for postoperative bleeding in order to select proper patients for outpatient thyroidectomy. This study aimed to investigate this issue using a national population-based register. Materia

Studies of how contextual factors influence teachers’ approaches to teaching have chiefly focused on face-to-face teaching in physical campus contexts. This study advances understanding of how applicable this knowledge is in digital contexts. The study explores how university teachers perceive the differences between teaching in physical campus contexts and the digital teaching contexts found in o

Ultralight lattice structures exhibit excellent mechanical performance and have been used widely. In structural design, the fundamental frequency is highly important. Therefore, a multiscale topology optimization method was utilized to optimize the fundamental frequency of multimaterial lattice structures in this study. Two types of optimization problems were studied, namely, maximizing the natura

Between 1908 and 1940, 431 young girls between 16 and 21 years of age were enrolled at Vejstrup Re-education Home for Girls. Through close readings of individual case records and other archival material from Vejstrup Re-education Home, this PhD thesis explores the ways in which the so-called “particularly difficult young girls” were perceived as problematic and how they were handled from 1908 to 1

Hippocampal subfield segmentation on in vivo MRI is of great interest for cognition, aging, and disease research. Extant subfield segmentation protocols have been based on neuroanatomical references, but these references often give limited information on anatomical variability. Moreover, there is generally a mismatch between the orientation of the histological sections and the often anisotropic co

Background and purpose — Total hip arthroplasty (THA) is increasing as treatment of displaced femoral neck fractures. Several studies compare hemiarthroplasty (HA) with THA, but results vary and few studies report on medical complications. We examined the outcome of THA and HA with a focus on medical complications, hip complications, and death. Patients and methods — Data from the Swedish Hip Arth