Creativity is a principal force of cognitive and communicational genesis that causes alteration of established rules and concepts (Heine/Kuteva 2007) and transgression of cultural borders (Lotman 1990). Artistic activity is normally taken for granted as creative, despite the fact that much artistic intention, is not necessarily aspiring to make any radical change of the circumstances in which it i

Despite being the main thriving force behind economic growth and industrial development, technological innovation remains highly concentrated on a handful of countries. It is therefore of a great interest to know how countries accumulate and develop their innovative capabilities, what kind of obstacles they need to overcome, and whether it is possible to identify opportunities to develop new areas

Under changing climate conditions, acceptable functionality of buildings and their adaptation to climate are required. More rain and extreme conditions in future make buildings and the built environment more vulnerable. There are currently several scenarios regarding possible future climatic conditions. Results from the impact analysis of climate change can be significantly affected by the selecte

Terrestrial ecosystems have absorbed roughly 30 % of anthropogenic CO2 emissions over the past decades, but it is unclear whether this carbon (C) sink will endure into the future. Despite extensive modeling and experimental and observational studies, what fundamentally determines transient dynamics of terrestrial C storage under global change is still not very clear. Here we develop a new framewor

Background and Objectives: The T-cell response to low-density lipoprotein (LDL) in the vessel wall plays a critical role in atherosclerotic plaque formation and stability. In this study, we used a new translational approach to investigate epitopes from human apolipoprotein B100 (ApoB100), the protein component of LDL, which triggers T-cell activation. We also evaluated the potential of two selecte

Childhood obesity is a serious public health problem in Mexico. In this study, childhoodspecific dietary patterns and their relationship with overweight-obesity prevalence, nutrient profiles and types of foods consumed were studied. A descriptive cross-sectional study of 724 randomly selected schoolchildren between 9 to 12 years old from Nayarit State, Mexico was performed. Data on anthropometric

We show that the eccentricity of every vertex in an undirected graph on n vertices can be computed in time n exp O(k*log(d)), where k is the treewidth of the graph and d is the diameter. This means that the diameter and the radius of the graph can be computed in the same time. In particular, if the diameter is constant, it can be determined in time n*exp(O(k)). This result matches a recent hardnes

Contemporary institutions engaged in extending micro-loans do not usually grant such loans to the poor due to the latters’ inability to provide appropriate collateral and their insufficient creditworthiness. In modern times the Dutch East-India Company created a financial instrument called the “transportbrief” which enabled poor employees of the Company to obtain loans on the financial market. The

I will take a recent CD-project as point of departure, a collaboration with the Turkish composer and electronic musician Erdem Helvaciolu. We did a series of recording sessions in Istanbul in December 2009 for which we agreed to use the Turkish makam as common point of departure in all the pieces. In this paper I will discuss the resistance of this material and specifically the relation between th

Sulfur single-wavelength anomalous dispersion (S-SAD) and halide-soaking methods are increasingly being used for ab initio phasing. With the introduction of in-house Cr X-ray sources, these methods benefit from the enhanced anomalous scattering of S and halide atoms, respectively. Here, these methods were combined to determine the crystal structure of BsDegV, a DegV protein-family member from Baci

The diversification of plant-feeding insects is seen as a spectacular example of evolutionary radiation. Hence, developing hypotheses to explain this diversification, and methods to test them, is an important undertaking. Some years ago, we presented the oscillation hypothesis as a general process that could drive diversification of this and similar interactions, through repeated expansions and co

This paper describes the methods used in the International Cancer Benchmarking Partnership Module 4 Survey (ICBPM4) which examines time intervals and routes to cancer diagnosis in 10 jurisdictions. We present the study design with defining and measuring time intervals, identifying patients with cancer, questionnaire development, data management and analyses. Design and setting: Recruitment of part