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The periodontal pathogen Porphyromonas gingivalis is highly resistant to the bactericidal activity of human complement, which is present in the gingival crevicular fluid at 70% of serum concentration. All thirteen clinical and laboratory P. gingivalis strains tested were able to capture the human complement inhibitor C4b-binding protein (C4BP), which may contribute to their serum resistance. Accor

Purpose. Patients with soft tissue sarcomas (STS) are at increased risk of second primary malignancies, including a second STS, but distinction between metastases and a second primary STS is difficult. Patients and Methods. Array-based comparative genomic hybridization (aCGH) was applied to 30 multiple STS of the extremities and the trunk wall from 13 patients. Different histotypes were present wi

This study attempted to use combined data from reconstructed digital breast tomosynthesis (DBT) volumes and density estimation of projection images to localise dense tissue inside the breast, using the assumption that the breast can be treated as consisting of only two types of tissue: fibroglandular (dense) and adipose (fatty). To be able to verify results, software breast phantoms generated usin

In this paper, physical limitations on bandwidth, realized gain, Q-factor and directivity are derived for antennas of arbitrary shape. The product of bandwidth and realizable gain is shown to be bounded from above by the eigenvalues of the long-wavelength, high-contrast polarizability dyadics. These dyadics are proportional to the antenna volume and are easily determined for an arbitrary geometry.

In this paper we give a method for constructing complete minimal submanifolds of the hyperbolic spaces H-m. They are regular fibres of harmonic morphisms from H-m with values in Riemann surfaces.

In this paper we will prove the uniqueness of a solution to Helmholtz' equation for two halfspaces of different media in $n$ dimensions. The theorem allows a finite number of bounded inhomogeneities in each half space. The surface separating the half spaces is assumed to be a cone of arbitrary cross section far away from the origin and is furthermore assumed to be smooth. We assume all space to be

EGFR-MEK-ERK signaling pathway has an established role in promoting malignant growth and disease progression in human cancers. Therefore identification of transcriptional targets mediating the oncogenic effects of the EGFR-MEK-ERK pathway would be highly relevant. Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a recently characterized human oncoprotein. CIP2A promotes malignant cell grow

Laminin-211 is a major constituent of the skeletal muscle basement membrane. It stabilizes skeletal muscle and influences signal transduction events from the myomatrix to the muscle cell. Mutations in the gene encoding the α2 chain of laminin-211 lead to congenital muscular dystrophy type 1A (MDC1A), a life-threatening disease characterized by severe hypotonia, progressive muscle weakness, and joi

This paper presents a method for using subjective factors to evaluate project success. The method is based on collection of subjective measures with respect to project characteristics and project success indicators. The paper introduces a new classification scheme for assessing software projects. Further, it is illustrated how the method may be used to predict software success using subjective mea

The life and culture of the nobility in Finland in the 18-th and early 19-th centuries in Finland. Political culture and relations, everyday life an networks in Finland, Sweden and western parts of Russia. In the centre you find the families Creutz, Glansenstierna and Sprengtporten.

This study examined variability of lip movements across repetitions of the same utterance as a function of age in Swedish speakers. Subjects were 37 typically developed Swedish children and adults (19 females, 18 males, aged 5-31 yr). Lip movements were recorded during 15-20 repetitions of a short Swedish phrase using articulography, with a sampling rate of 200 Hz. After correction for head moveme

Most primary immunodeficiencies (PIDs) have overlapping signs and symptoms - presenting a challenge for diagnosis. The information available from the Internet for over 200 PIDs is scattered between numerous services and databases. Patient information has been collected in different patient registries. Several software tools have been developed in order to build the databases, expert systems and ot

Since treatment for latent cryptococcal infection (CI) before starting antiretroviral therapy (ART) reduces mortality in HIV-infected subjects, screening for cryptococcal antigen (CrAg) in blood is recommended for individuals with CD4 cell counts < 100 cells/µL in regions with high CI prevalence. We assessed CrAg screening using the lateral flow assay in HIV-infected adults eligible for ART in cen

The platelet-derived growth factor (PDGF) alpha and beta receptors undergo dimerization as a consequence of ligand binding. Depending on the PDGF isoform (PDGF-AA, -AB or -BB), homodimers or heterodimers of receptors are formed. In this study, we have used transfected porcine aortic endothelial cells, coexpressing cDNAs for the alpha receptor and the beta receptor at comparable levels, to investig