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Bronchodilator response of advanced lung function parameters depending on COPD severity

Background: COPD is defined as partly irreversible airflow obstruction. The response pattern of bronchodilators has not been followed in advanced lung function parameters. Purpose: The aim of this study was to investigate bronchodilator response pattern in advanced lung function parameters in a continuous fashion along forced expiratory volume in 1 second (FEV1) percent predicted (%p) in COPD pati

Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis

Background: The complement system has been implicated in pathogenesis of systemic sclerosis (SSc). The goal of the present study was to evaluate improved complement biomarkers in SSc. Methods: The presence of C4d, reflecting activation of the classical/lectin pathways, C3bBbP corresponding to activation of the alternative pathway, and soluble terminal complement complexes (all complement pathways)

Effects of the web behavior change program for activity and multimodal pain rehabilitation : Randomized controlled trial

Background: Web-based interventions with a focus on behavior change have been used for pain management, but studies of Web-based interventions integrated in clinical practice are lacking. To emphasize the development of cognitive skills and behavior, and to increase activity and self-care in rehabilitation, the Web Behavior Change Program for Activity (Web-BCPA) was developed and added to multimod

Studies of electron diffusion in photo-excited Ni using time-resolved X-ray diffraction

We show that the heat deposition profile in a laser-excited metal can be determined by time-resolved X-ray diffraction. In this study, we investigated the electron diffusion in a 150 nm thick nickel film deposited on an indium antimonide substrate. A strain wave that mimics the heat deposition profile is generated in the metal and propagates into the InSb, where it influences the temporal profile

Immune responses link parasite genetic diversity, prevalence and plumage morphs in common buzzards

The evolution and maintenance of conspicuous phenotypic polymorphisms has challenged evolutionary ecologists for centuries. Polymorphisms in pleiotropic cascades or genetic linkage may lead to correlations of life history traits such as immunity, parasite infection levels, pigmentation and lifetime reproductive success. The common buzzard Buteo buteo is a bird of prey occurring in several plumage

Vagueness and Goodness Simpliciter

Recently a lot has been written on the topic of value incomparability. While there is disagreement on how we are to understand incomparability, most seem to accept Ruth Chang's claim that all comparisons must proceed in some specific respect. Call this the Requirement for Specification. Interestingly, even though most seem to accept this requirement, next to nothing has been written on it. In this

Three presents : On the multi-temporality of territorial production and the gift from John Soane

Territoriality has primarily been seen as a spatial rather than temporal phenomenon. In this paper, we want to investigate how time functions in territorialising processes. In particular, we are attracted by the multi-temporality that is co-present in each process of territorialisation (i.e. processes in which time and space are used as means of measure, control and expression). The article is div

Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells

Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell surface. When the dosing of oligomers was stopped the intracellular calcium returned to basal levels o

Bodily symptoms in patients with post traumatic stress disorder : A comparative study of traumatized refugees, Danish war veterans, and healthy controls

Background: Post traumatic stress disorder (PTSD) is associated with increased general health symptoms and patients suffer from numerous bodily complaints such as increased pain, increased muscular tension, and restricted breathing. Methods and material: This study applied the Body Awareness Movement Quality and Experience scale (BAS MQ-E) in assessing and comparing bodily symptoms, including move

Heel ulcers do heal in patients with diabetes

A heel ulcer is considered to be a serious complication in patients with diabetes, and there is limited information regarding outcome. In most of the literature, a poor prognosis is described. The aim of this study was to investigate a large cohort of ulcers located in the heel in patients with diabetes. Seven hundred and sixty-eight patients [median age 73 (17-98)], presenting with a heel ulcer a

The Eltringham organ and a new thoracic gland: Ultrastructure and presumed pheromone function (Insecta. Myrmeleontidae)

Eltringham's organ is a club-like projection from the posterior margin of hind-wings of some myrmeleontid insects. It bears laterally directed setae, each having a specialized epidermal cell beneath, which gives off secretion into a sub-setal lumen. The lumen continues into the wall of the moat-like socket of the setae. Eltringham's organ fits into an excavation of the lateral body wall connected

Monoamine-containing neurons in the optic ganglia of crustaceans and insects

With the fluorescence method of Falck and Hillarp, the presence and localization of monoaminergic neurons in the optic ganglia of several crustaceans and insects have been investigated. It was found that in both classes the monoaminergic terminals, when present, appeared (especially in the medullae externa and interna of the crustaceans and the medulla of the insects) in strata specific for each s

On the cavity receptor organ (X-organ or organ of Bellonci) of Artemia salina (Crustacea, Anostraca)

The cavity receptor organ (previously X-organ or organ of Bellonci) of Artemia salina consists of ciliated neurons whose cilia protrude into a cavity beneath the cuticle. The neuronal dendrites penetrate a giant accompanying cell and epidermal cells before entering the cavity. The cavity beneath the cuticle, the ciliated neurons and the connexion with the medulla terminalis justifies a homologizatThe cavity receptor organ (previously X-organ or organ of Bellonci) of Artemia salina consists of ciliated neurons whose cilia protrude into a cavity beneath the cuticle. The neuronal dendrites penetrate a giant accompanying cell and epidermal cells before entering the cavity. The cavity beneath the cuticle, the ciliated neurons and the connexion with the medulla terminalis justifies a homologizat

Some observations on the internal morphology of Hansen's nauplius Y (Crustacea)

The internal morphology of the crustacean larval form that Hansen (1899) called nauplius y has revealed a remarkably advanced early nauplius. The nervous system is well developed and differentiated. It is connected with the anlagen of the compound eyes. A presumed filamentous base of the SPX-organ connects with these. The nauplius eye is present in a three-partite form with two retinula cells in e

The nauplius eye and frontal organs of the non-Malacostraca (Crustacea).

The present work is a continuation of the morphological studies of the nauplius eye and frontal organs of the Crustacea. The previous papers on this topic comprised the Decapoda (ELOFSSON, 1963) and the Malacostraca (ELOFSSON, 1965). Its has been found that the nauplius eye and frontal organs of the Crustacea are separated into four different types. These comprise the Phyl-lopoda, Anostraca, Maxil

Sami law in late modern legal contexts

This chapter demonstrates the dynamics within current Nordic legal cultures; that is the oppositional struggle between ideological and legal forces and their influences in societal development. It analyses the different, especially Swedish, contexts, which has created this new late modern legal culture regarding the Sami and Sami law. During the past three decades, Sami law has been increasingly v

POROUS POLYMERS AND DESIGNED SORBENTS FOR APPLICATIONS IN BIOMEDICAL RESEARCH

Everyday millions of bioanalyses are performed in clinical laboratories, hospitals and research centers, where technicians and bio-analysts utilize analytical chemistry principles and instruments to serve medicine and biomedical research. A method routinely used for sample preparation in bioanalysis is solid-phase extraction (SPE). SPE is a simple method to extract an analyte from a sample matrix

Spatiotemporal characterization of ultrashort optical vortex pulses

We use a spiral phase plate to generate few-cycle optical vortices from an ultrafast titanium:sapphire oscillator and characterize them in the spatiotemporal domain with a recently introduced technique based on spatially resolved Fourier transform spectrometry. The performance of this simple approach to the generation of optical vortices is analysed from a wavelength-dependent perspective as well