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The added value of devices to pelvic floor muscle training in radical post-prostatectomy stress urinary incontinence: A systematic review with metanalysis

PURPOSE: To investigate the role of pelvic floor devices (e.g., biofeedback, electrical stimulation, magnetic stimulation, or their combination) as adjunctive treatments in pelvic floor muscle training (PFMT) in stress urinary incontinence (SUI) after radical prostatectomy.MATERIALS AND METHODS: A systematic review with meta-analysis. We searched for randomised controlled trials (RCTs) and prospec

In vivo gene expression profile of Haemophilus influenzae during human pneumonia.

Haemophilus influenzae is a major cause of community-acquired pneumonia. While studied extensively in various laboratory models, less is known about the cell function while inside the human lung. We present the first analysis of the global gene expression of H. influenzae while the bacteria are in the lung during pneumonia ( in vivo conditions) and contrast it with bacterial isolates that have be

A retrospective multicenter cohort study of the association between anti-Factor Xa values and death, thromboembolism, and bleeding in patients with critical COVID-19

BACKGROUND: Patients with critical COVID-19 have a high risk of thromboembolism, but intensified thromboprophylaxis has not been proven beneficial. The activity of low-molecular-weight heparins can be monitored by measuring anti-Factor Xa. We aimed to study the association between anti-Factor Xa values and death, thromboembolism, and bleeding in patients with critical COVID-19.METHOD: This retrosp

Optimization of b-value Acquisition and Parameter Estimation of Intravoxel Incoherent Motion Measurements

Strålterapi är en vanligt förekommande behandling som ges till hälften av cancerpatienterna i landet. I fallet för prostatacancer, som utgör den vanligaste diagnosen, beror ofta cancerrelaterade dödsfall på återkomst av sjukdomen efter genomförd behandling. Vår hypotes är att detta kan minskas genom att identifiera strålrestistenta volymer i prostatan och öka stråldosen till dessa. Tyvärr finns deRadiotherapy is commonly used for cancer treatment, given to approximately half of all cancer patients in Sweden. Despite its widespread usage, there is currently no non-invasive and reliable imaging method that can identify regions of radiation resistance. These regions may be identified by hypoxia, given that radiobiological research has demonstrated a significant correlation between oxygen leve

Corrigendum to “How accurately can subject-specific finite element models predict strains and strength of human femora? Investigation using full-field measurements” (Journal of Biomechanics (2016) 49(5) (802–806), (S0021929016301865) (10.1016/j.jbiomech.2016.02.032))

The authors regret to report that an issue in the proposed code resulted in errors in Figs. 3 and 4 Table 2. The authors apologize for any inconvenience caused. The error has been corrected in this corrigendum. To maintain comparable results, two minor changes in the methods were also implemented, namely: – The principal strains to determine the yield and fracture state were averaged over a 3 mm r

Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs

There is a clinical need for conceptually new treatments that target the excessive activation of inflammatory pathways during systemic infection. Thrombin-derived C-terminal peptides (TCPs) are endogenous anti-infective immunomodulators interfering with CD14-mediated TLR-dependent immune responses. Here we describe the development of a peptide-based compound for systemic use, sHVF18, expressing th

Covid-19: What Determines Policy Responses Across Europe?

This chapter analyses responses of European policymakers to the Covid-19 pandemic’s first and second waves. It is based on an empirical analysis where patterns are sought between contextual factors and policy responses. The results shows that that macroeconomic conditions and policy interactions appear to matter more than countries’ number of Covid-19 cases. The level of government indebtedness ca

Ett leende går inte att digitalisera: En kvalitativ undersökning av kombinationen av traditionell och digital marknadsföring i arbetet med kundrelationer.

Tidigare forskning lyfter fram betydande fördelar med den digitala marknadsföringen, samtidigt som det framförs att det är av vikt att behålla den traditionella marknadsföringen. Vad som är viktigt, oavsett om strategin baseras på traditionell eller digital marknadsföring, är en strategi som kommunicerar ett tydligt varumärke och anpassar sig efter kunden. Därmed menar tidigare forskning att en ko

Resilient water innovation for smart economy with membrane technology

The European project ‘REsilient WAter Innovation for Smart Economy’ (REWAISE) aims to establish a novel ‘smart water ecosystem’ by integrating an advanced digital infrastructure for decentralized water services and decision-making, engaging all stakeholders to highlight the actual value of water. The approach will reduce the consumption of freshwater and energy while also recovering valuable nutri

ENVRI-FAIR D7.8: Test and validation at EOSC level

This deliverable focuses on capturing the current status of testing and validation of services from the RI’s and ENVRI-Hub itself, that are both exposed to EOSC. This means that services are in scope that are shared via the ENVRI Catalogue of Services to the EOSC marketplace. The EOSC validation activities will check the readiness of the ENVRI-FAIR services at the sub-domain and cluster level for

Acoustofluidic Properties of Polystyrene Microparticles

Acoustophoresis has become a powerful tool to separate microparticles and cells, based on their material and biophysical properties, and is gaining popularity in clinical and biomedical research. One major application of acoustophoresis is to measure the compressibility of cells and small organisms, which is related to their contents. The cell compressibility can be extracted from the acoustic mob

The Art of Phenomena Construction : A Framework for Coming Up with Research Phenomena beyond ‘the Usual Suspects’

Despite the centrality of research phenomena, the process of their definition is often neglected and reduced to a simple choosing of pre-established subjects of interest. However, good research not only includes empirical work aimed at more or less ‘given as fact’ phenomena. It also involves phenomena construction: that is, the process of generating and establishing phenomena to investigate and th

Elastic Net Regression for Prosthesis Control in Short Residual Limb Amputees: Performance and Generalizability

Utforskning av flerkanalig intramuskulär elektromyografi (iEMG) för förbättrad protesstyrning Ingress: Med inspiration från hur hjärnan koordinerar muskler för att skapa rörelser, något som kallas muskelsynergier, utforskar detta examensarbete användningen av flerkanalig iEMG för att med större precision uppskatta isometriska krafter från handen Brödtext: Människans rörelser styrs av komplexa saThis Master's thesis in Biomedical Engineering investigates the performance and generalizability of linear regression models in context of prosthesis control for short residual limb amputees. This thesis uses intramuscular electromyography data, and a regression and emplys a regression technique called Elastic Net Regression - a technique that combines L1 and L2-regularization - to predict 1-D

Critical Scaling in Particle Systems and Random Graphs

The purpose of this thesis is to study the behavior of macro-systems through their micro-parameters. In particular, we are interested in finding critical scaling in various models.Paper I investigates the influence of discrete-time collisions on particle dynamics. By analyzing two models — one involving external forces and friction, and another incorporating collisions with lighter particles — a n