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Multi-scale Measurement of (Amorphous) Polymer Deformation: Simultaneous X-ray Scattering, Digital Image Correlation and In-situ Loading

This paper presents a method to investigate the behaviour of polymers on different scales during deformation using simultaneously collected synchrotron X-ray scattering, digital image correlation (DIC) and tensile loading. The method is demonstrated through experiments made on specimens of amorphous polycarbonate. Deformation is measured in-situ, simultaneously across different scales from the mac

When More Depletion Offsets the Ego Depletion Effect

The ego depletion effect has been consistently replicated using the typical paradigm that consists of two consecutive tasks. However, striking contradiction exists in studies employing multiple tasks. The aim of the current study is to replicate previous studies following a similar procedure and design in a sample of participants from a non-western cultural background (Chinese), while strictly con

Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants

Troublesome involuntary movements in the absence of dopaminergic medication, so-called off-medication dyskinesias, are a serious adverse effect of fetal neural grafts that hinders the development of cell-based therapies for Parkinson's disease. The mechanisms underlying these dyskinesias are not well understood, and it is not known whether they are the same as in the dyskinesias induced by L-dopa

Concomitant use of warfarin and ticagrelor as an alternative to triple antithrombotic therapy after an acute coronary syndrome.

Treatment with warfarin in combination with clopidogrel has been shown to reduce the incidence of major bleeding as compared to triple antithrombotic therapy (TT; warfarin, clopidogrel and aspirin). However, there are uncertainties regarding the risk for thrombosis since poor-responsiveness to clopidogrel is common. Ticagrelor is a more potent platelet inhibitor, but data supporting concurrent use

Phase Measurement of Resonant Two-Photon Ionization in Helium

We study resonant two-color two-photon ionization of helium via the 1s3p P-1(1) state. The first color is the 15th harmonic of a tunable Ti:sapphire laser, while the second color is the fundamental laser radiation. Our method uses phase-locked high-order harmonics to determine the phase of the two-photon process by interferometry. The measurement of the two-photon ionization phase variation as a f

Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine

Many brominated flame retardants (BFRs)-including polybrominated diphenyl ethers (PBDEs)-have been shown to persist in the environment, and some have been associated with adverse health effects. The aim of the present study was to quantify serum concentrations of common brominated flame retardants in Inuit men from across Greenland, and in men from Warsaw, Poland and Kharkiv, Ukraine. Serum was sa

Assessment and modification of sub-cell-fix method for re-initialization of level-set distance function

Sub-cell-fix re-initialization method was proposed by Russo and Smereka (J. Comput. Phys. 2000; 163: 51-67) as a modification to the re-distancing, algorithm Of Sussman et al. (J. Comput. Phys. 1994; 114: 146-159) that determines the distance function from an interface known as the zero level-set. The principal goal of sub-cell-fix method is to compute the distance function of the cells adjacent t

NBSPred: A support vector machine-based high throughput pipeline for plant resistance protein NBSLRR prediction.

The nucleotide binding site-leucine-rich repeats (NBSLRR) belong to one of the largest known families of disease resistance genes that encode resistance proteins (R-protein) against the pathogens of plants. Various defence mechanisms have explained the regulation of plant immunity, but still, we have limited understanding about plant defence against different pathogens. Identification of R-protein

Adjuvant chemotherapy in endometrial cancer.

The indications for adjuvant therapy in endometrial cancer are briefly reviewed. The importance of systemic adjuvant therapy is emphasized. A short summary of randomized studies on adjuvant chemotherapy versus radiotherapy and on adjuvant sequential chemotherapy plus radiotherapy versus radiotherapy alone is given. On the basis of the present results from randomized trials, a combination of adjuva

Inducing the oxidative stress response in Escherichia coli improves the quality of a recombinant protein: magnesium chelatase ChlH

The approximately 150kDa ChlH subunit of magnesium chelatase from Oryza sativa, Hordeum vulgare and Chlamydomonas reinhardtii have been heterologously expressed in Escherichiacoli. The active soluble protein is found as both a multimeric and a monomeric form. The multimeric ChlH appears to be oxidatively damaged but monomer production is favoured in growth conditions that are known to cause an oxi

A Case of Depressive Personality Disorder: Aligning Theory, Practice, and Clinical Research

Depressive personality disorder (DPD) is highly studied and common in clinical settings. Nevertheless, it is rife with controversies and often overshadowed by major depression and dysthymia with which it shares many similarities but also is clinically distinct. Possibly as a result, DPD is underdiagnosed and misunderstood in clinical care. Thus the goal of this practice review is to present a case

Anthropogenic impact on amorphous silica pools in temperate soils

Human land use changes perturb biogeochemical silica (Si) cycling in terrestrial ecosystems. This directly affects Si mobilisation and Si storage and influences Si export from the continents, although the magnitude of the impact is unknown. A major reason for our lack of understanding is that very little information exists on how land use affects amorphous silica (ASi) storage in soils. We have qu

Assessment of genetic and pheromonal diversity of the Cydia strobilella species complex (Lepidoptera: Tortricidae)

Combining pheromone trapping and genetic analyses can be useful whentrying to resolve complexes of closely related insect taxa that are difficult to distinguishbased on morphological characters. Nearctic and Palearctic populations of the spruceseed moth, Cydia strobilella L., have been considered taxonomically synonymoussince 1983, but more recent work revealing distinct sex pheromones for Canadia

Forests, savannas, and grasslands: bridging the knowledge gap between ecology and Dynamic Global Vegetation Models

The forest, savanna, and grassland biomes, and the transitions between them, are expected to undergo major changes in the future due to global climate change. Dynamic global vegetation models (DGVMs) are very useful for understanding vegetation dynamics under the present climate, and for predicting its changes under future conditions. However, several DGVMs display high uncertainty in predicting v

Slow Aromatic Ring Flips Detected Despite Near-Degenerate NMR Frequencies of the Exchanging Nuclei.

Aromatic ring flips of Phe and Tyr residues are a hallmark of protein dynamics with a long history in molecular biophysics. Ring flips lead to symmetric exchange of nuclei between sites with distinct magnetic environments, which can be probed by NMR spectroscopy. Current knowledge of ring-flip rates originates from rare cases in which the chemical shift difference between the two sites is sufficie

Lower urinary tract symptoms in children with anorectal malformations with rectoperineal fistulas.

AIM:The aim was to describe the frequency of lower urinary tract symptoms (LUTS) in children with anorectal malformations with rectoperineal fistulas (ARM-P), as compared with healthy controls based on gender.METHOD:LUTS were defined using the 2014 definitions of the International Children's Continence Society. Data were collected at 2 tertiary pediatric surgery centers in 2 countries from all chi

Positron emission tomography in malignancies of the liver, pancreas and biliary tract - indications and potential pitfalls.

Abstract Malignancies of the hepato-pancreatico-biliary (HPB) system are relatively common and generally characterized by a dismal prognosis. Positron emission tomography (PET) is a functional imaging technique that has emerged as an important modality in oncological decision-making. The principal radiopharmaceutical in PET imaging is the glucose analog (18)F-fluorodeoxyglucose, which is able to d