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The Human Endogenous Protection System against Cell-Free Hemoglobin and Heme Is Overwhelmed in Preeclampsia and Provides Potential Biomarkers and Clinical Indicators.

Preeclampsia (PE) complicates 3-8% of all pregnancies and manifests clinically as hypertension and proteinuria in the second half of gestation. The pathogenesis of PE is not fully understood but recent studies have described the involvement of cell-free fetal hemoglobin (HbF). Hypothesizing that PE is associated with prolonged hemolysis we have studied the response of the cell-free Hb- and heme de

Field scale organic farming does not counteract landscape effects on butterfly trait composition

We tested how dispersal capacity, host plant specificity and reproductive rate influenced the effects of farming system and landscape composition on butterfly species richness and abundance. In no case did variation in these traits explain species responses to organic farming, indicating that all species benefit equally. In contrast, butterflies with high mobility and reproductive rate were dispro

Influence of Polymorphisms in the RANKL/RANK/OPG Signaling Pathway on Volumetric Bone Mineral Density and Bone Geometry at the Forearm in Men

We sought to determine the influence of single-nucleotide polymorphisms (SNPs) in RANKL, RANK, and OPG on volumetric bone mineral density (vBMD) and bone geometry at the radius in men. Pairwise tag SNPs (r (2) a parts per thousand yen 0.8) for RANKL (n = 8), RANK (n = 44), and OPG (n = 22) and five SNPs near RANKL and OPG strongly associated with areal BMD in genomewide association studies were pr

To jointly negotiate a personal decision: a qualitative study on information literacy practices in midwifery counselling about contraceptives at youth centres in Southern Sweden

Introduction. The study is part of a project in which young women’s evaluation of information sources before choosing a contraceptive is studied. It focuses on young women meeting midwives for counselling about contraceptives. Conversations are information literacy practices with both parties negotiating about needed and appropriate information on which they will base decisions. Method. Ten conve

The heart in the critically ill patient- an echocardiographic study

The thesis describes aspects of left ventricular systolic and diastolic function examined with echocardiography in patients with systemic inflammation and shock. Background: Myocardial depression is a well-known complication in critically ill patients with shock. Echocardiography is increasingly used for assessing left ventricular (LV) function in these patients. Aims: 1) To describe the feasibili

Separating Movement and Gravity Components in an Acceleration Signal and Implications for the Assessment of Human Daily Physical Activity

Introduction: Human body acceleration is often used as an indicator of daily physical activity in epidemiological research. Raw acceleration signals contain three basic components: movement, gravity, and noise. Separation of these becomes increasingly difficult during rotational movements. We aimed to evaluate five different methods (metrics) of processing acceleration signals on their ability to

The secret lives of tourists: Delays, disappointments and daydreams

Tourist research on life in "The Experience Economy" has led to a focus oil the eventful cold dramatic, on ways of packaging and marketing "great experiences" that turn a heritage into all event, a city into desires, a museum into all adventure. There is a lot of talk about the production of great atmospheres and exciting events, but tourist life is of course full of non-events, indifferent or bad

Copy number variants in the kallikrein gene cluster.

The kallikrein gene family (KLK1-KLK15) is the largest contiguous group of protease genes within the human genome and is associated with both risk and outcome of cancer and other diseases. We searched for copy number variants in all KLK genes using quantitative PCR analysis and analysis of inheritance patterns of single nucleotide polymorphisms. Two deletions were identified: one 2235-bp deletion

Micro-mechanisms of a laminated packaging material during fracture

The micro-mechanisms of fracture in a laminate composed of an aluminium foil and a polymer film are considered in this study. The laminates as well as the individual layers, with and without premade centre-cracks, were tensile tested. Visual inspection of the broken cross-sections shows that failure occurs through localised plasticity. This leads to a decreasing and eventually vanishing cross-sect

Photobleaching-Insensitive Fluorescence Diagnostics in Skin and Brain Tissue

In this paper, we investigate the possibility of using accurate prediction models for the prediction of protoporphyrin bleaching dynamics to achieve photobleaching-insensitive methods to improve the evaluation of data in an existing clinical fluorescence-guided resection technique. To simulate the scenario, measurements were carried out in vivo on skin of healthy volunteers using a compact fiber-b

An Evil King 'Thing', Rising, Falling and Multiplying in Trucker Culture

Paraphrasing Slavoj Zizek (1991: 65), the paper proposes that: 'The Scania Truck does not exist': it is nothing but 'the symptom of passionate users', its power of fascination masks the void of its nonexistence'. Along the same line of reasoning, it argues, again paraphrasing Zizek, that 'the customized Scania truck is becoming the sinthome of its user'. (c.f. Zizek, 1991: 137). The paper does so

Wet glued laminated beams using side boards of Norway spruce

In a previous research project, carried out during the years 2006-2008, the possibility to manufacture wet glued laminated beams using ungraded laminations of Norway spruce side boards was investigated with very promising results.In the project presented in this report, the performance of the wet glued beams has been further investigated and developed as regards grading of side board laminations,

Vibronic origin of long-lived coherence in an artificial molecular light harvester.

Natural and artificial light-harvesting processes have recently gained new interest. Signatures of long-lasting coherence in spectroscopic signals of biological systems have been repeatedly observed, albeit their origin is a matter of ongoing debate, as it is unclear how the loss of coherence due to interaction with the noisy environments in such systems is averted. Here we report experimental and

Modelling Tundra Vegetation Response to Recent Arctic Warming

The Arctic land area has warmed by > 1 A degrees C in the last 30 years and there is evidence that this has led to increased productivity and stature of tundra vegetation and reduced albedo, effecting a positive (amplifying) feedback to climate warming. We applied an individual-based dynamic vegetation model over the Arctic forced by observed climate and atmospheric CO2 for 1980-2006. Averaged ove

Upper petal lip colour polymorphism in Collinsia heterophylla (Plantaginaceae): genetic basis within a population and its use as a genetic marker.

Understanding the genetics of a polymorphic trait is important to predict its likely evolution. In Collinsia heterophylla, the upper petal lip colour can be either be white or white with a purple band, while the lower petal lip colour is invariably purple. Because the corolla is only partly polymorphic, the polymorphism can not have evolved due to a mutation where a pigment was lost in the entire