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Serum amyloid P component : A new biomarker for low sperm concentration?

Serum amyloid P component (SAP) is present in seminal plasma, on spermatozoa, and in different tissues of the male reproductive tract, but its function is not known. The aims of this study were to determine if the concentration of SAP in seminal plasma is associated with commonly assessed semen parameters and to investigate if SAP could be a new, indirect biomarker for these parameters. In a cross

Guided Aspiration for Determining the Microbiological Aetiology of Aortic Vascular Graft and Endograft Infections

ObjectiveOpen and endovascular aortic repair may be complicated by aortic vascular graft or endograft infection (VGEI). Confirming the microbiological aetiology is a key element in providing the best available treatment to patients with a VGEI. The primary aim of this study was to describe the technique of direct aneurysm sac guided aspiration (DASGA) in determining the microbiological aetiology i

Sharing Cities Sweden: Key Findings and Amplifying Impacts

Sharing Cities Sweden was a national program to help establish Sweden as a country that actively and critically works with the sharing economy in cities. Between 2017- 2021, it was a key initiative of Viable Cities - the strategic innovation program for smart and sustainable cities in Sweden.Sharing Cities Sweden developed and published a diversity of reports and outputs that synthesize the activi

A new pipeline for the normalization and pooling of metabolomics data

Pooling metabolomics data across studies is often desirable to increase the statistical power of the analysis. However, this can raise methodological challenges as several preanalytical and analytical factors could introduce differences in measured concentrations and variability between datasets. Specifically, different studies may use variable sample types (e.g., serum versus plasma) collected, t

Noise-free on-demand atomic frequency comb quantum memory

We present an extension of the atomic frequency comb protocol that utilizes the Stark effect to perform noise-free, on-demand, control. An experimental realization of this protocol was implemented in the Pr3+:Y2SiO5 solid-state system, and a recall efficiency of 38% for a 0.8 μs storage time was achieved. Experiments were performed with both bright pulses as well as weak-coherent states, the latte

Occurrence of gamma-trace in the calcitonin-producing C-cells of simian thyroid gland and human medullary thyroid carcinoma

gamma-Trace, a microprotein occurring in neuroendocrine cells, was demonstrated by immunohistochemical technique to be present in the calcitonin-producing C-cells of normal simian thyroid gland and of human medullary thyroid carcinoma. A comparatively high concentration of gamma-trace was demonstrated in tissue extract of neoplastic C-cells. The immunoreactive protein found in the extract had a mo

The complete amino acid sequence of human complex-forming glycoprotein heterogeneous in charge (protein HC) from one individual

The complete amino acid sequence of the single polypeptide chain of human complex-forming glycoprotein heterogeneous in charge (protein HC) isolated from a single individual is reported with the supporting data. The primary structure was determined by automatic degradation of the intact chain and of fragments obtained by chemical and enzymatic degradations of the native or reduced and S-carboxymet

Sustainabilty and retail marketing : Corporate, product and store perspectives

This paper investigates sustainability in retailing based on three different perspectives: i) the overall corporate management, ii) the development of an attractive product range, iii) the daily in-store management and activities. The purpose is to identify a set of main themes for each perspective, investigate contradictions and areas of conflict, and discuss how to bridge the perspectives. A qua

Multi-objective testing of different brass alloy components for DFM

This paper investigates the differences of leaded and low-lead brasses in terms of mechanical and thermal properties, machinability and product strength using physical testing and simulations. The information can be used in companies for Design for Manufacturability (DFM) while designing processes for lead free brass. The novelty of this research is to combine data from different testing methods t

Analytical and Experimental Determination of the Ra Surface Roughness during Turning

In this article an analytical equation for calculating the theoretical arithmetic mean surface roughness, Ra, in the case of turning using a tool with a circular nose radius is presented. The deviation that often occurs between the expected and the obtained surface roughness during these machining operations is investigated. Influence of the minimum chip thickness is discussed especially in regard

Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy

Appropriate regulation of autophagy is crucial for clearing toxic proteins from cells. Defective autophagy results in accumulation of toxic protein aggregates that detrimentally affect cellular function and organismal survival. Here, we report that the microRNA miR-1 regulates the autophagy pathway through conserved targeting of the orthologous Tre-2/Bub2/CDC16 (TBC) Rab GTPase-activating proteins

Calcium in Cell-Extracellular Matrix Interactions

In multicellular organisms, the cells are surrounded by persistent, dynamic extracellular matrix (ECM), the largest calcium reservoir in animals. ECM regulates several aspects of cell behavior including cell migration and adhesion, survival, gene expression and differentiation, thus playing a significant role in health and disease. Calcium is reported to be important in the assembly of ECM, where

On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis

The present study addresses the roles of heparan sulfate (HS) proteoglycans and chondroitin sulfate (CS) proteoglycans in the development of zebrafish pharyngeal cartilage structures. uxs1 and b3gat3 mutants, predicted to have impaired biosynthesis of both HS and CS because of defective formation of the common proteoglycan linkage tetrasaccharide were analyzed along with ext2 and extl3 mutants, pr

The Influence the Uncut Chip Thickness has on the Stagnation Point in Orthogonal Cutting

The effect of cutting data on the stagnation zone of a machining operation is of great interest since it governs the material flow around the cutting edge. The material flow has a significant influence on the mechanical properties of the machined surface. This paper presents a numerical model that is able to determine the effect that the uncut chip thickness has on the stagnation zone and the conn

Sustainability Performance Indicators at Shop Floor Level in Large Manufacturing Companies

This article investigates sustainability in the performance measurement systems of Swedish manufacturing companies. It builds on a previous study that documents relatively few direct environmental indicators at shop floor level, which raises questions about possible indirect links between existing indicators and the environment that could be used to improve the environmental aspect of company's su

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Traditional economic growth measures have not taken into account the negative externalities of productive activities. In this context, the so-called natural resource curse should be redefined beyond positive, negative, slow or fast growth rates. This article, using the case of Chile as a reference, estimates the effect of mining exports on two fundamental indicators of economic development: the fo

An isogeometric finite element approach to fibre-reinforced composites with fibre bending stiffness

In the modelling of fibre-reinforced composites, it is well established to consider the fibre direction in the stored energy in order to account for the transverse isotropy of the overall material, induced by a single family of fibres. However, this approach does not include any length scale and therefore lacks in the prediction of size effects that may occur from the fibre diameter or spacing. By