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NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. Previous work showed that glucose activates the transcription factor Nuclear Factor of Activated T cells (NFAT) in arteries ex vivo. NF

Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study

Myeloid leukemia of Down syndrome has a better prognosis than sporadic pediatric acute myeloid leukemia. Most cases of myeloid leukemia of Down syndrome are characterized by additional cytogenetic changes besides the constitutional trisomy 21, but their potential prognostic impact is not known. We, therefore, conducted an international retrospective study of clinical characteristics, cytogenetics,

Adaptation as a Means of Reflecting upon Immersivity and Self-Referentiality

In this article, I will apply parts of the method introduced by Linda Hutcheon in her recently reedited book A Theory of Adaptation (2010) and try to answer the question “why” an adaptation is made. I will particularly study three complex cases of adaptation, which might even put into question the definition of adaptation itself, but I will concentrate on aspects related to immersion and self-refe

Folkhögskola 2.0 - ett kompetensutvecklingsprojekt. Extern utvärdering.

Folkhögskola 2.0 är ett kompetensutvecklingsprojekt i Skåne inom ramen för Europeiska socialfondens programområde 1. Projektet är på många sätt ett omfattande projekt. Det har ett brett, övergripande syfte som spänner över flera områden. I projektet är aktörer från flera folkhögskolor inblandade i ledningsarbetet och det berör ett stort antal medarbetare från olika yrkeskategorier. Projektet har p

A relationship between migraine and biliary tract disorders: findings in two Swedish samples of elderly twins

Objectives - To investigate whether there is a relationship between the clinical occurrence of migraine and biliary tract disorders (BTD) and to study whether there is a genetic influence on such an association. Materials and Methods - The near lifetime morbidity for migraine and BTD was examined in two Swedish twin-samples: OCTO-Twin (149 MZ and 202 DZ pairs; 234 men, 468 women; 80 years of age o

Shifting between self-governing and being governed: a qualitative study of older persons' self-determination

Background: Older persons' right to exercise self-determination in daily life is supported by several laws. Research shows that older persons' self-determination is not fully respected within the healthcare sector. In order to enable and enhance older persons' self-determination, extensive knowledge of older persons' self-determination is needed. The aim of this study was to explore experiences of

Feedback from soil inorganic nitrogen on soil organic matter mineralisation and growth in a boreal forest ecosystem

Current nitrogen (N) deposition rates are considerably higher than during pre- industrial times and the growing interest in forest fertilisation requires better understanding of how the N and carbon (C) cycles interact. This study is based on experimental data showing how Scots pine (Pinus sylvestris L.) forests respond to single or consecutive pulse doses of N. The data were used to support the i

Precision in 2D temperature measurements using the thermographic phosphor BAM

Investigation of optimized spatial precision for surface temperature measurements is performed. The temperature is measured by means of two-color ratio imaging with ICCD cameras, using the thermographic phosphor BAM. The precision in temperature is put in relation to the spatial resolution, two quantities which involve a trade-off in this case: the more spatial smoothing the better precision, but

Relationship between distal radius fracture malunion and arm-related disability: A prospective population-based cohort study with 1-year follow-up

Background: Distal radius fracture is a common injury and may result in substantial dysfunction and pain. The purpose was to investigate the relationship between distal radius fracture malunion and arm-related disability. Methods: The prospective population-based cohort study included 143 consecutive patients above 18 years with an acute distal radius fracture treated with closed reduction and eit

Two microvillar organs, new to Crustacea, in the Mystacocarida.

The mystacocarid crustacean Derocheilocaris typica has two microvillar organs, one new, the other previously unappreciated in crustacean literature. The first is situated on the head-shield and consists of three pairs of cells: one with microvilli and a ballooned nucleus; one smaller and without special features; the third large and investing the other two and extending down to the foregut. We cal

Microwave CMOS VCOs and Front-Ends - using integrated passives on-chip and on-carrier

Popular Abstract in Swedish De ökande kraven på högre datahastigheter inom trådlös kommunikation ställer allt högre krav på både radiosändare och mottagare, då dessa behöver utnyttja fler frekvensband med större bandbredd vid högre frekvenser. Fokus i denna avhandling ligger på högfrekvensdelen av radiomottagaren, som består av lågbrusförstärkare, blandare, och oscillatorer vid mikrovågsfrekvenserThe increasing demand for high data rates in wireless communication systems is increasing the requirements on the transceiver front-ends, as they are pushed to utilize more and wider bands at higher frequencies. The work in this thesis is focused on receiver front-ends composed of Low Noise Amplifiers (LNAs), Mixers, and Voltage Controlled Oscillators (VCOs) operating at microwave frequencies. Tra

Methane exchange in a boreal forest estimated by gradient method

Forests are generally considered to be net sinks of atmospheric methane (CH4) because of oxidation by methanotrophic bacteria in well-aerated forests soils. However, emissions from wet forest soils, and sometimes canopy fluxes, are often neglected when quantifying the CH4 budget of a forest. We used a modified Bowen ratio method and combined eddy covariance and gradient methods to estimate net CH4

Low-complexity error correction of Hamming-code-based LDPC codes

Ensembles of binary random LDPC block codes constructed using Hamming codes as constituent codes are studied for communicating over the binary symmetric channel. These ensembles are known to contain codes that asymptotically almost meet the Gilbert-Varshamov bound. It is shown that in these ensembles there exist codes which can correct a number of errors that grows linearly with the code length, w

Subarctic ecosystem responses to climate, catchment and permafrost dynamics in the Holocene

This thesis assesses aspects of the wetland development, permafrost dynamics and associated changes in carbon and nutrient cycling of the Stordalen Mire in northern Sweden. Various ecological and biogeochemical analyses of one peat and two lake sediment sequences were conducted, including analyses of organic matter and carbonate content, mosses, diatoms, testate amoebae, pigments, carbon and nitro