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OBJECTIVE: To investigate markers of endothelial activation in muscle biopsies from rheumatoid arthritis (RA) patients with and without extra-articular manifestations (ExRA). PATIENTS AND METHODS: Nine consecutive ExRA patients were compared with nine RA controls without ExRA, matched for age, sex and duration of RA. Muscle biopsies were obtained from the lateral vastus or anterior tibial muscle.

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Here we have examined the enzymes cyclooxygenase (COX)-2 and 15-hydroxyprostaglandin dehydrogenase (15-OH PGDH) in pregnant human cervix. In biopsies taken transvaginally after preterm and term elective cesarean sections and vaginal deliveries, the levels of mRNA coding for COX-2 and 15-OH PGDH were assessed by Northern blotting. The cellular localization of the COX-2 and 15-OH PGDH proteins was d

Recent developments of surrogate assays for human hematopoietic stem cells (HSC) have facilitated efforts at improving HSC gene transfer efficiency. Through the use of xenograft transplantation models, such as nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice, successful oncoretroviral gene transfer to transplantable hematopoietic cells has been achieved. However, because of the l

Resonance effects at the Ga 3p photoabsorption threshold have been observed in photoemission spectra recorded from thin film InxGa1-xN alloys. The spectra display satellites of the main Ga 3d emission line, and the intensity of these satellites resonate at this threshold. The satellites are associated with a 3d(8) state, and have previously been observed for the semiconductors GaN, GaAs, and GaP.

The objective of pubertal induction in children with hypogonadism is to mimic spontaneous puberty in terms of physical and psychological development. In a clinical observation study, we induced puberty in 15 girls with hyper- or hypogonadotropic hypogonadism using low doses of transdermal estradiol patches attached only during the night and compared the estradiol concentrations obtained with those

I artikeln ges en beskrivning över VA-sektorns utveckling under 1990-talet

The deep structure of the gabbro-anorthosite-rapakivi granite ("AMCG-type") Korosten Pluton (KP) in the northwestern Ukrainian Shield was studied by 3-D modelling of the gravity and magnetic fields together with previous seismic data. The KP occupies an area of ca. 12,500 km(2) and comprises several layered gabbro-anorthositic intrusions enveloped by large volumes of rapakivi-type granitoids. Betw

Popular Abstract in Swedish Korsningsintensiteten for en stationär stokastisk process är ett värdefullt verktyg när man studerar fördelningen för våghöjder och för maxima av havsnivån. Denna avhandling betraktar två approximationstekniker för fall då korsningsintensiteten inte kan ges exakt.Båda tekniker använder en asymptotisk expansion, och första och andra ordningens termer i denna approximatioThe crossing rate of a stationary random process is a valuble tool when studying crest hight distributions and maxima of sea level elevation. This thesis considers two approximation techinques for cases when the crossing rate cannot be exactly computed. Both techniques use an asymptotic expansion, and the first and second order terms in these expansions are given explicitly. Paper A describes how

We present a systematic study of different reconstructions obtained after deposition of Au on the (root 3 x root 3)- R30 degrees- 4H- SiC( 0001) surface. For 1-2 monolayers ( ML) Au and annealing temperature T-anneal similar to 675 degrees C, a 3 x 3 reconstruction was observed. For 4 ML Au and T-anneal similar to 650 degrees C, a ( 2 root 3 x 2 root 3)- R30 degrees. reconstruction appeared, while

Two experiments have been performed using the Ni-58(S-32,3p) reaction at 135 MeV with Gammasphere and the Microball to study the high-spin structure of the transitional nucleus Nb-87. The first experiment using a thin target provided a considerable extension and refinement of the level scheme, as well as firm spin assignments from directional correlation of oriented nuclei. Sub-picosecond lifetime

Gorbachev’s environmental policies aimed at raising the masses and incite them to action for the common good. A side effect was the introduction of the factor information in Soviet society. Thereby centrifugal political forces were released. These forces rallied behind environmental issues of local, and thus local ethnic significance. The ensuing political mobilization was nationalist in spirit.

OBJECTIVE— The purpose of this study was to assess the role of household conditions for the progression to diabetes in women with impaired glucose tolerance (IGT). RESEARCH DESIGN AND METHODS— A total of 461 women, aged 50–64 years, with IGT defined by an oral glucose tolerance test, had baseline advice on physical exercise, diet, smoking, and alcohol habits. Physical examination, blood tests, an

Background Job strain (high demands and low decision latitude) and the DID genotype of an I/D polymorphism in the adrenergic alpha(2B)-receptor have been associated with hypertension, respectively. We hypothesized that the I/D polymorphism interacts with external stress, such as job strain, in the development of hypertension. Methods A sample of 3045 employed men and women from the population coho