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The impact of peripheral artery disease on major adverse cardiovascular events following myocardial infarction

Aims: Peripheral artery disease (PAD) constitute a high-risk with adverse clinical outcomes. We aimed to investigate the cardiovascular outcomes following myocardial infarction (MI). Methods and results: This nationwide, Danish register-based follow-up study includes all patients experiencing an MI between 2000 and 2017. Patients with and without PAD were compared. Multivariable logistic regressio

Accuracy of magnetic resonance imaging staging of tumour and nodal stage in rectal cancer treated by primary surgery : a population-based study

Aim: The preoperative stage of rectal cancer is an important prognostic factor affecting treatment recommendations. Currently, magnetic resonance imaging (MRI) is used for clinical staging to identify patients who should be recommended for neoadjuvant oncological treatment. The aim of this work was to investigate the accuracy of the preoperative T- and N-stage and also involvement of the mesorecta

Luminescence of ODC(II) in quartz and cristobalite glasses

The results of the optical spectroscopy of twofold coordinated silicon centers – ODC(II) in quartz and cristobalite glasses are presented. The luminescence and excitation spectra attributed to different local symmetry of ODC(II) were investigated under synchrotron excitation in the VUV region. The observed differences in the luminescence and excitation spectra of ODC(II) are caused by the environmThe results of the optical spectroscopy of twofold coordinated silicon centers – ODC(II) in quartz and cristobalite glasses are presented. The luminescence and excitation spectra attributed to different local symmetry of ODC(II) were investigated under synchrotron excitation in the VUV region. The observed differences in the luminescence and excitation spectra of ODC(II) are caused by the environm

Sensor Networks Tdoa Self-Calibration : 2d Complexity Analysis and Solutions

Given a network of receivers and transmitters, the process of determining their positions from measured pseudoranges is known as network self-calibration. In this paper we consider 2D networks with synchronized receivers but unsynchronized transmitters and the corresponding calibration techniques, known as Time-Difference-Of-Arrival (TDOA) techniques. Despite previous work, TDOA self-calibration i

Introduction

There is a flourishing use of long-term analysis around the economic challenges generated by natural resources exploitation (Badia-Miró et al., 2015; Bebbington et al., 2018; Mosley, 2017).

Pain in rheumatoid arthritis : a seven-year follow-up study of pain distribution and factors associated with transition from and to chronic widespread pain

Objective: To study transitions from and to chronic widespread pain (CWP) over 7 years in patients with rheumatoid arthritis (RA). Method: Two postal questionnaires were sent to patients included in the BARFOT (Better Anti-Rheumatic Pharmacotherapy) study, the first in 2010 and the second in 2017. The questionnaires assessed pain, number of tender and swollen joints, functional disability, health-

Neuron-specific enolase and long-term neurological outcome after OHCA – A validation study

Aims: To investigate what NSE levels predict long-term neurological prognosis at 24, 48 and 72 hours after ROSC in a cohort of out-of-hospital cardiac arrest and to validate previously suggested NSE cut-offs, including the latest ERC guidelines (2021). Methods: Patients admitted to intensive care units in four hospitals in Southern Sweden between 2014–2018 were included. Blood samples were handled

Influence of Cutting Edge Geometry on Force Build-up Process in Intermittent Turning

In the intermittent turning and milling processes, during the entry phase the cutting edges are subjected to high impact loads that can give rise to dynamical and strength issues which in general cause tool life reduction. In this study the effect of geometrical features of the cutting tool on the force generation during the entry phase is investigated. Cutting forces are measured by a stiff dynam

Reduced ability to produce reflex-evoked neurogenic inflammation, a sign of decreased defense against COVID-19 infection?

Background: A histamine skin prick test (SPT) generally evokes a wheal and a flare. The present study was initiated by an observation that histamine did not evoke a flare around a wheal in the skin of an 86-year-old man. Could that be of relevance to the findings that old men are prone to a more severe COVD-19 infection with a higher mortality than young ones?. Materials and methods: Histamine SPT

Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside

Galectin-8 has gained attention as a potential new pharmacological target for the treatment of various diseases, including cancer, inflammation, and disorders associated with bone mass reduction. To that end, new molecular probes are needed in order to better understand its role and its functions. Herein we aimed to improve the affinity and target selectivity of a recently published galectin-8 lig

Transductive Image Segmentation : Self-training and Effect of Uncertainty Estimation

Semi-supervised learning (SSL) uses unlabeled data during training to learn better models. Previous studies on SSL for medical image segmentation focused mostly on improving model generalization to unseen data. In some applications, however, our primary interest is not generalization but to obtain optimal predictions on a specific unlabeled database that is fully available during model development

Space and the emotional topography of populism in Turkey : The case of Hagia Sophia

Over the past decade, as ruling Justice and Development Party (AKP) initiated Turkey’s authoritarian populist turn, it sought to derive legitimacy through extra-institutional avenues, notably the emotional appeal to the repressed “people”, advancing the party’s socio-political vision, countering the arguments of its political opponents and reaching out to, and inspiring its constituency. Turkey’s

A new protocol for exercise testing in COPD; improved prediction algorithm for WMAX and validation of the endurance test in a placebo-controlled double bronchodilator study

Two new protocols have been developed for bicycle exercise testing in chronic obstructive pulmonary disease (COPD) with an individualized cardiopulmonary exercise test (ICPET) and subsequent customized endurance test (CET), which generate less interindividual spread in endurance time compared with the standard endurance test. Main objectives of this study were to improve the prediction algorithm f

How economic expectations shape preferences for national independence : Evidence from Greenland

This paper investigates how economic expectations shape voting intentions in a hypothetical independence referendum in Greenland, a self-governing region of the Kingdom of Denmark. I identify the causal effect of economic expectations by randomly exposing respondents to a prime informing on Greenland's current fiscal deficit. Respondents exposed to the information are 43% more likely to oppose ind

Feasibility of extracorporeal on-line large-scale plasma adsorptions on protein A-sepharose columns in cancer patients

The feasibility of extracorporeal adsorption of 1.5-3 L plasma on protein A-Sepharose was investigated in six patients with advanced cancer. Anticoagulation with heparin was associated with respiratory distress syndrome in two patients, most likely caused by complement activation as indicated by a transient leukopenia during plasma reinfusion and appearance of C3 degradation products in the extrac

Crime Prevention Based on the Strategic Mapping of Living Conditions

This paper presents a theoretically and methodologically grounded GIS-based model for the measurement and mapping of an index of living conditions in urban residential areas across Sweden. Further, the model is compared and evaluated using the Swedish Police's assessment of crime-exposed areas. The results indicate that the geographically measured vulnerable living conditions overlap to a large exThis paper presents a theoretically and methodologically grounded GIS-based model for the measurement and mapping of an index of living conditions in urban residential areas across Sweden. Further, the model is compared and evaluated using the Swedish Police’s assessment of crime-exposed areas. The results indicate that the geographically measured vulnerable living conditions overlap to a large ex

Evaluating the added value of multi-variable calibration of SWAT with remotely sensed evapotranspiration data for improving hydrological modeling

Hydrological processes in a watershed consist of multiple sub-processes (such as plant growth, evapotranspiration, water yield, and soil–water balance) that have complex interactions. The common practice of calibrating hydrological models against only a single variable (e.g., streamflow) can lead to parameter uncertainty (also known as equifinality), resulting in significant uncertainties in the r