This volume contains innovative papers that target the linguistic status of topic at the interface between grammar and discourse. The purpose of the volume is to discuss the universal properties of topics and, at the same time, to document the range of discourse-semantic and grammatical variation within this phenomenon in European languages. The volume is structured accordingly: (i) theoretical fo

This paper discusses early medieval stone towers on Gotland. It summarizes the scholarly interpretations of their functions and dating,and analysis the towers in different spatial settings; towers at farmsteads, at churches and at harbours. Generally, we should see the towers on Gotland as concrete symbols of the presences of different types of elite. The towers at churches and farms reflects the

Urban agglomeration is an important strategy used to promote economic development and urbanization in China. Understanding the structure of urban agglomeration is therefore essential for policy-makers and planners. In this study, the Beijing–Tianjin–Hebei urban agglomeration (BTHUG) is explored through a proposed spatial network analytical framework and a large mobile phone data set (over 20 milli

Gram-negative bacteria from the genus Acinetobacter are responsible for life-threating hospital-related infections such as pneumonia, septicemia, and meningitis, especially in immunocompromised patients. Worryingly, Acinetobacter have become multi- and extensively drug resistant (MDR/XDR) over the last few decades. The complement system is the first line of defense against microbes, thus it is hig

Based on interviews with three generations of professors reflecting upon their development as early career researchers in an outstanding research environment within the STEMfield, this study aimed to explore how they had coped with relationship conflicts in the environment, how this had an impact on their team socialisation, and how their development was framed by their supervisors’ leadership. Us

Traditionally entrepreneurship and small business research has been regarded as a practical and relevant research field, providing knowledge to be used to solve various societal problems. As the field is becoming more and more institutionalized in the academic system, scientific rigour in research has been emphasized at the expense of relevance. In the chapter the authors strives to show that prod

Background: Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and efficacious in reducing OFF-time in two pivotal trials in patients with PD and end-of-dose motor fluctuations. The OpiCapone Effect on motor fluctuations

The mechanisms of coronavirus disease-2019 (COVID-19)–related myocardial injury comprise both direct viral invasion and indirect (hypercoagulability and immune-mediated) cellular injuries. Some patients with COVID-19 cardiac involvement have poor clinical outcomes, with preliminary data suggesting long-term structural and functional changes. These include persistent myocardial fibrosis, edema, and

BackgroundThe Dyspnoea-12 (D12) and Multidimensional dyspnea profile (MDP) are commonly used instruments for assessing multiple dimensions of breathlessness but have not been validated in older people in the population. The aim of this study was to validate the D12 and MDP in 73-years old men in terms of the instruments’ underlying factor structures, internal consistency, and validity.MethodsA pos

Low-lying states in the odd-Z isotopes Ac13289221 and Pa13491225 have been studied using α-particle and αγ-coincidence spectroscopy in the Pa225→Ac221→Fr217 decay chain. Ground-state spin and parity assignments of Iπ = 5/2- are proposed for both Ac221 and Pa225, with the odd proton occupying the ω = 5/2 orbital of the quadrupole-octupole deformed shell model in both nuclei. In Ac221, excited state

Sleep duration is emerging as an important modifiable risk factor for morbidity and mortality. We assessed the association between sleep duration and cancer incidence and mortality among Japanese adults using data from six population-based cohorts with 271 694 participants. During a total follow-up period of about 5.9 million person-years, we identified 40 751 incident cancer cases and 18 323 canc

Smoke from western North American wildfires reached the stratosphere in large amounts in August 2017. Limb-oriented satellite-based sensors are commonly used for studies of wildfire aerosol injected into the stratosphere (OMPS-LP (Ozone Mapping and Profiler Suite Limb Profiler) and SAGE III/ISS (Stratospheric Aerosol and Gas Experiment III on the International Space Station)). We find that these m

We provide an abstract approach to approximation with a wide range of regularity classes X in spaces of pseudocontinuable functions Kp Θ, where Θ is an inner function and p > 0. More precisely, we demonstrate a general principle, attributed to A. Aleksandrov, which asserts that if a certain linear manifold X is dense in Kq Θ for some q > 0, then X is in fact dense in Kp Θ for all p > 0. Moreover,

Deficiencies in software or computer chips cause computers or smartphones to crash and allow hackers to steal passwords. Automated test procedures could avoid these problems. However, the computing power and cooling requirements of conventional computers increase exponentially with the size of the problem, so that the technological limits for solving these problems will soon be reached. The EU pro

Early adolescence is the period of the emergence of most mental disorders contributing significantly to the mental health burden globally, including India. The major challenges in India are early identification of mental health problems, treatment gap, lack of professionals, and interventions that address the same. Our review aimed to assess the effectiveness of mental health interventions among a