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Discovery of novel AQP3-inhibitors

Vatten är nödvändigt för att den mänskliga kroppen ska fungera. För att vattnet ska kunna transporteras in och ut ur cellerna behöver det komma igenom cellmembranet, vilket det bland annat gör via en särskild klass av proteiner som fungerar som vattenkanaler – akvaporinerna. Akvaporiner finns överallt i vår kropp och är viktiga för många biologiska funktioner såsom metabolism och återfuktning av hAquaporins (AQPs) are a family of transmembrane proteins, mainly mediating water transport over the cell membrane in various parts of the body. The aquaporins AQP3 and AQP7 are both part of the subfamily aquaglyceroporins, which apart from water conduct small non-polar solutes such as glycerol. AQP3 overexpression or malfunction has been connected to skin and lung cancer and potential AQP3 inhibit

Optical System Design and Optimization for Digital Light Processing Headlights

An optical system for digital light processing car headlamps was designed and optimized in this project. The specifications include five lens elements and a field of view of 15 degrees horizontally and 7.5 degrees vertically. The system consists of an illumination module and a projection lens assembly. A high-brightness LED source and a rectangular light integrator ensure uniform illumination on t

Rejected and Resentful: How Job-Seekers Connect Negative Recruitment Process Experiences and Brands

Purpose: This study aims to contribute to the understanding of how job-seekers relate their negative recruitment process experiences to brands. Design/Methodology/Approach: This study adopts a qualitative approach using semi-structured interviews, conducted with thirteen current university students actively seeking employment in degree-requiring fields. The data is abductively analysed through th

Exploration of a Hybrid Procedural Animation Framework

This thesis explores a hybrid procedural animation framework that combines physics-based constraints with artistically tunable parameters to generate diverse, real-time character locomotion. Addressing the limitations of traditional keyframing and opaque data-driven methods, the system employs a hierarchical parameter set-ranging from high-level style descriptors (e.g., "energy level") t

Mellan hjärta och paragraf: En studie om barnförhörsledares känslohantering i en rättslig kontext

The primary task of child forensic interviewers is to secure evidence without causing the child discomfort. Evidence obtained through incorrect interview techniques risks being denied in court. Research has shown that negative emotions such as sadness and anger can affect the interrogation negatively. The aim of this study was to gain new knowledge about the complexity that child interviewers face

Goodbye Heritage, Hello Stranger

This study explores consumer perceptions of heritage brands following a revolutionary rebrand, with a focus on adapting the Consumer Perceived Value (CPV) theory. Building on Wuestefeld et al.’s (2012) framework, the research incorporates the disruptive nature of revolutionary rebranding to extend the theoretical understanding of CPV in a heritage branding context. Guided by a relativist ontology

Våld i ungas parrelationer - En kvalitativ studie utifrån yrkesverksammas perspektiv

I Sverige har var femte ungdom mellan 16-24 år blivit utsatt för våld i en parrelation. Denna uppsats behandlar det sexuella och fysiska våld som flickor utsätts för i parrelationer motiverat utifrån att statistiken visar att det är en grupp som särskilt drabbas av dessa våldsformer. Syftet är att bidra med kunskap eftersom den svenska forskningen inom fältet är mycket begränsad. Förhoppningen är

The Making of Employee Ambassadorship in the Public Sector: Quantitative Study on Individual and Organizational Drivers

This thesis explores the phenomenon of employee ambassadorship in the public sector within the framework of internal branding. The aim is to identify the factors that facilitate or hinder employee ambassadorship, particularly on an individual and organizational level. The study challenged the dominant managerial perspective on internal branding by establishing an employee-centered approach which r

From Code to Content: How AI-generated Visual Content Shapes Consumers' Perceived Brand Image

Purpose: This study aims to investigate how consumer attitudes toward AI-generated content, in the form of pictures and videos, shape how they perceive a brand’s image. Research question: How is consumers’ perception of a brand’s image shaped by the use of AI-generated visual content? Theoretical Framework: Breckler’s ABC model, which conceptualizes the notion of attitudes, is used to ensure we

More than just a label: The impact of the vegan label on product perception and consumption intentions across health consciousness levels

Purpose: The study aims to examine whether health consciousness, as a cognitive heuristic, influences the impact of vegan labels, as external cues, on product attribute perceptions such as taste, health, and environmental friendliness, as well as on consumption intentions. As consumers face cognitive limitations when evaluating food products, this research aim to contribute to the understanding of

Digitalization of Danish Daycare Institutions

Fatima, f, 34, parent: “It is a small home for our children. They spend many hours here. To us, it is not just daycare. We don’t just come here and drop off our children and say goodbye, then come back in a few hours. They have to feel that this is a home to them”. This ethnographic study of Danish daycares analyses how information is being shared between parents and daycare staff, how conflict is

Brottsoffer, fördomar & sekundär viktimisering: Fördomar om polisen och viljan att anmäla sexualbrott

This study investigates the relationship between public perceptions of rape myths, secondary victimization, and the willingness to report a sexual assault in a Swedish context. A literature review was conducted to map the current state of the research, which revealed that most previous studies originate from North America and emphasize the role of institutional responses, especially by the police.

A Day By the Beach - Reimagining Coastal Tourism in the Age of Climate Change, Sri Lanka

As climate change accelerates, rising sea levels and eroding shorelines are reshaping our coastal landscapes. Short-term fixes, such as beach nourishment and offshore breakwaters, are proving increasingly ineffective and costly. In nations like Sri Lanka, where tourism is a vital pillar of the economy and heavily dependent on beaches, these transient measures have become financially unsustainable.

Bias correction of diagnostics data from IoT devices

Selection bias in non-probability samples presents a significant challenge in IoT device di- agnostics data analysis, where incomplete or systematically missing data can compromise the validity of analytical insights. Our project proposes a comprehensive statistical frame- work to correct for that bias, using real-world data from Axis Communications AB. The project explores three primary methodolo

När gränsen mellan nytt och begagnat suddas ut

Sammanfattning Syfte: Syftet med studien är att öka förståelsen om second hand online genom att analysera hur utformningen av ISHP möjliggör användarengagemang, samt hur användare uppfattar och interagerar med plattformarna. Teoretiskt ramverk: Analysen baseras på Zhao, Zhang, Tang och Songs (2021) modell för digitala affordanser, där handlings-, effekt- och motivationsaffordanser används för att

Smart Enough to Start Up?: How Educational Background Shapes Swedish small business founders’ entrepreneurial capabilities

Forskningsfråga: Hur påverkar en akademisk ekonomiutbildning, jämfört med enbart en gymnasieexamen, svenska småföretagsgrundares entreprenöriella förmågor? Syfte: Studien syftar till att undersöka hur utbildningsbakgrund påverkar svenska småföretagsgrundares entreprenöriella förmågor. Fokus ligger på att jämföra grundare med en akademisk ekonomiutbildning med dem som endast har gymnasieutbildningResearch question: How does having an academic business degree compared to only a high school diploma shape Swedish small business founders’ entrepreneurial capabilities? Purpose: To examine how small business founders’ educational background influences their entrepreneurial capabilities in the Swedish context, specifically comparing those with an academic business degree to those with only a hig

Trump I Spegeln: En kvalitativ analys av personalisering och medialisering i svensk nyhetsrapportering

Denna uppsats syftar till att undersöka vilka normer och värderingar som finns i svensk nyhetsmedia, med särskilt fokus på begreppen personalisering och medialisering. Genom en kvalitativ innehållsanalys av åtta nyhetsartiklar från fyra av Sveriges största dagstidningar (Dagens Nyheter, Svenska Dagbladet, Expressen och Aftonbladet) analyseras hur medierapporteringen kring en specifik händelse – Tr

They Shoot, They Score: The New Rules of Marketability Madness

This study aims to quantitatively examine the impact of on-court, off-court, and university-related factors on athlete marketability. It further investigates whether gender moderates these relationships. A quantitative approach was chosen, utilizing secondary data collected from collegiate basketball athletes’ social media profiles and university rosters for the 2024-2025 season. Generalized Linea