Every person diagnosed with tuberculosis (TB) needs to initiate treatment. The World Health Organization estimated that 61% of people who developed TB in 2021 were included in a TB treatment registration system. Initial loss to follow-up (ILTFU) is the loss of persons to care between diagnosis and treatment initiation/registration. LINKEDin, a quasi-experimental study, evaluated the effect of 2 in

Biocompatible, tough, and photoluminescent hydrogels are highly desirable for biomedical applications in vivo. Herein, hybrid hydrogels prepared from silk fibroin (SF) and polyacrylic acid (PAA) and complexed with europium, named as SF-PAA-Eu3+ hydrogels, exhibit good comprehensive properties. Owing to the intensive molecular interactions among SF, PAA, and Eu3+, SF-PAA-Eu3+ hydrogels show a great

A handheld infrared camera was used to visualize heating and cooling of magnetic brakes in drop towers and roller coasters. The images also display the cooling effect of trees and the warming effect of clouds. This paper discusses what can be discerned from the photos with connections to data from data sheets, as well as from accelerometer and barometer sensors. The heating and cooling proces

The Western Gneiss Region (WGR) is a Precambrian basement domain in the Scandinavian Caledonides and one of the world's largest high- and ultrahigh-pressure terranes. The south–central WGR underwent regional eclogite facies metamorphism 415–400 Ma ago when Baltica subducted beneath Laurentia, during the Scandian orogeny. Eclogites in the WGR group into two traditional types: (1) Precambrian mafic

Aims/hypothesis: The aim of this study was to determine whether BMI in early childhood was affected by the COVID-19 pandemic and containment measures, and whether it was associated with the risk for islet autoimmunity. Methods: Between February 2018 and May 2023, data on BMI and islet autoimmunity were collected from 1050 children enrolled in the Primary Oral Insulin Trial, aged from 4.0 months to

Background: Childhood cancer survivors are at risk of subsequent gliomas and meningiomas, but the risks beyond age 40 years are uncertain. We quantified these risks in the largest ever cohort. Methods: Using data from 69,460 5-year childhood cancer survivors (diagnosed 1940–2008), across Europe, standardized incidence ratios (SIRs) and cumulative incidence were calculated. Results: In total, 279 g

Continuous task engagement generally leads to vigilance decrement and deteriorates task performance. However, how conflict effect is modulated by vigilance decrement has no consistent evidence, and little is known about the underlying neural mechanisms. Here we adopted an electroencephalogram dataset collected during a prolonged flanker task to examine the interactions between vigilance and congru

Importance: Patients with melanoma are selected for sentinel lymph node biopsy (SLNB) based on their risk of a positive SLN. To improve selection, the Memorial Sloan Kettering Cancer Center (MSKCC) and Melanoma Institute Australia (MIA) developed predictive models, but the utility of these models remains to be tested. Objective: To determine the clinical utility of the MIA and MSKCC models. Design

The automation of map labeling is an ongoing research challenge. Currently, the map labeling algorithms are based on rules defined by experts for optimizing the placement of the text labels on maps. In this paper, we investigate the feasibility of using well-labeled map samples as a source of knowledge for automating the labeling process. The basic idea is to train deep learning models, specifical

Stochastic reconstruction is widely employed for effective and flexible imitation of Gas Diffusion Layers (GDLs), e.g., to facilitate the study of their properties. However, the reconstruction often overlooks crucial factors such as fiber curvature, fiber stack arrangement, and fiber anisotropy. Consequently, the impact of these structural characteristics remains poorly understood. In this study,

The bacterial ribosome is an essential drug target as many clinically important antibiotics bind and inhibit its functional centers. The catalytic peptidyl transferase center (PTC) is targeted by the broadest array of inhibitors belonging to several chemical classes. One of the most abundant and clinically prevalent resistance mechanisms to PTC-acting drugs in Gram-positive bacteria is C8-methylat

In this paper, we aggregate, analyze, and exemplify several metrics for the information value. The metrics vary by absolute value, normalizations, or full probabilistic quantification. The normalization of the information value encompasses the division by (1) the expected and maximized utility of the base scenario (usually without additional information), (2) by the system performance, or (3) by t

Purpose: Glaucoma is a heterogeneous group of optic neuropathies that potentially may be associated with other cerebral neurodegenerative processes leading to dementia. However, prior studies have been inconsistent. We examined dementia risks after glaucoma diagnosis in a large population-based cohort. Design: National matched cohort study. Participants: A total of 324 730 persons diagnosed with g

Background: Surgical sentinel lymph node biopsy (SLNB) is routinely used to reliably stage axillary lymph nodes in early breast cancer (BC). However, SLNB may be associated with postoperative arm morbidities. For most patients with BC undergoing SLNB, the findings are benign, and the procedure is currently questioned. A decision-support tool for the prediction of benign sentinel lymph nodes based

Background: Few individuals with alcohol use disorders receive treatment. Primary care has been suggested as an arena for early treatment for these disorders. Aim: To evaluate whether the presence of a specialized addiction nurse can increase alcohol-related physician consultations in a primary care setting. Method: This controlled intervention study included one intervention and one control prima

Ground-based geophysical surveys were conducted at eight mine-tailings repositories during 2021 and 2022 to help preparing an inventory of potential sources of critical raw materials in mine-waste. Geophysical methods included ERT, DCIP, RMT, and tTEM. In this study, we show results obtained on two of the sites as an example. Integration of models of electrical properties, geological observations,

The paper explores synergies by bundling High-Capacity Transport - Intelligent Access - Zero Emission Vehicle reforms. State of the art is analyzed, and research questions are formulated. One joint policy framework is proposed and applied to three use cases: one vehicle, one real use case, and one scenario for the whole of EU. In the later, the cost savings 2024 to 2028 from allowing longer and/or

The development of lipid nanoparticle (LNP) based therapeutics for delivery of RNA has triggered the advance of new strategies for formulation, such as high throughput microfluidics for precise mixing of components into well-defined particles. In this study, we have characterised the structure of LNPs throughout the formulation process using in situ small angle x-ray scattering in the microfluidic

Configuring reconfigurable intelligent surfaces (RISs) based on a practical RIS model is a fundamental problem in RIS-assisted wireless transmission. In this work, we propose a concept named optimal phasor (OP), a latent quantity that can considerably help the practical model-based RIS configuration. Under such a concept, we can design versatile algorithms that are applicable to different RIS mode