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Infrequent marine-freshwater transitions in the microbial world

Until recently, the evolutionary relationships between marine and freshwater microbes were unclear, but the use of molecular phylogenies is beginning to shed light on this subject. An increasing amount of studies are showing that marine and freshwater microbes (including viruses) are usually not closely related, often grouping into distinct marine and freshwater phylogenetic clusters, similar to w

PHYSICOCHEMICAL CHARACTERIZATION OF FRUIT AND VEGETABLE FIBER SUSPENSIONS. II: EFFECT OF VARIATIONS IN HEAT TREATMENT

The pectin content in the soluble and insoluble fractions of fiber suspensions from carrot, potato pulp and apple heat treated in four different ways was determined together with the particle size distribution, water-holding capacity (WHC), morphology and rheological properties of the fiber suspensions. In the carrot and apple suspensions, where beta-elimination was favored, the soluble pectin inc

Nonlinear analysis of crack widths in reinforced concrete

Former research indicates that the crack width close to the bar can be a better indicator for the risk for reinforcement corrosion than, as current concrete codes impose, the crack width at the concrete surface. In this paper a finite-element model is used to increase the understanding of how the crack width varies at different levels from the reinforcement and how different mechanisms control thi

Capacitive biosensor for quantification of trace amounts of DNA

A flow injection capacitive biosensor system to detect trace amounts DNA has been developed based on the affinity binding between immobilized histone and DNA. Histones from calf thymus and shrimp were immobilized on gold electrodes covered with self-assembled monolayer (SAM) of thioctic acid. Each of these histones was used to detect DNA from calf thymus, shrimp and Escherichia coli. The studies i

The significance of lipid peroxidation in cardiovascular disease

Background: The metabolic syndrome describes a cluster of cardiovascular risk factors that frequently appear together. Its diagnosis is generally based on several well-recognized indicators in clinical practice, such as abdominal obesity, elevated triglycerides, reduced high-density lipoprotein, raised blood pressure, and elevated fasting plasma glucose. Today, decisive importance must be attached

Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.

Retinoid X receptors (RXRs) are heterodimerization partners for many nuclear receptors and also act as homodimers. Heterodimers formed by RXR and a nonpermissive partner, e.g. retinoic acid receptor (RAR) and vitamin D receptor (VDR), can be activated only by the agonist of the partner receptor. In contrast, heterodimers that contain permissive partners, e.g. liver X receptor (LXR) and peroxisome

Maternal educational level, parental preventive behavior, risk behavior, social support and medical care consumption in 8-month-old children in Malmo, Sweden

Background: The social environment in which children grow up is closely associated with their health. The aim of this study was to investigate the relationship between maternal educational level, parental preventive behavior, parental risk behavior, social support, and use of medical care in small children in Malmo, Sweden. We also wanted to investigate whether potential differences in child medic

Detection and identification of anomalies in wireless mesh networks using Principal Component Analysis (PCA)

Anomaly detection is becoming a powerful and necessary component as wireless networks gain popularity. In this paper, we evaluate the efficacy of PCA based anomaly detection for wireless mesh networks. PCA was originally developed for wired networks. Our experiments show that it is possible to detect different types of anomalies in an interference prone wireless environment. However, the sensitivi

Ribosomal History Reveals Origins of Modern Protein Synthesis

The origin and evolution of the ribosome is central to our understanding of the cellular world. Most hypotheses posit that the ribosome originated in the peptidyl transferase center of the large ribosomal subunit. However, these proposals do not link protein synthesis to RNA recognition and do not use a phylogenetic comparative framework to study ribosomal evolution. Here we infer evolution of the

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

Microglia and infiltrating leukocytes are considered major producers of tumor necrosis factor (TNF), which is a crucial player in cerebral ischemia and brain inflammation. We have identified a neuroprotective role for microglial-derived TNF in cerebral ischemia in mice. We show that cortical infarction and behavioral deficit are significantly exacerbated in TNF-knock-out (KO) mice compared with wi

Open compared with 2-portal endoscopic carpal tunnel release: a 5-year follow-up of a randomized controlled trial.

PURPOSE: The purpose of this investigation was to extend the previously reported short-term randomized trial of open and endoscopic carpal tunnel release in patients with carpal tunnel syndrome (CTS) to compare outcomes 5 years after surgery. METHODS: In a single-center randomized controlled trial, 128 patients (25 to 60 years) with clinically diagnosed and electrophysiologically confirmed idiopat

Monolithic cryogels with open porous structure and unique double-continuous macroporous networks

A novel approach to create macroporous cryogels (or gels synthesized at sub-zero temperatures) with increased mechanical strength is presented. The cryogels with unique double-continuous macroporous networks were prepared via sequential freezing-thawing, when the new cryogel was synthesized inside the interconnected macropores of the preformed or primary cryogel. The prepared double-continuous mac

Molecular size of riverine dissolved organic matter influences coastal phytoplankton communities

Dissolved organic matter (DOM) concentrations in many northern European freshwater systems have been increasing during the past decades. DOM affects the marine plankton community where rivers discharge into the sea. Large DOM molecules have been suggested to be more available to aquatic plankton than smaller ones due to their more recent origin in the degradation process. In this study, we investi

Artificial receptors

Herein I will provide a brief overview of artificial receptors with emphasis on molecularly imprinted polymers (MIPs) and their applications. Alternative techniques to produce artificial receptors such as in silico designed and modelled polymers as well as different receptors designed using libraries of more or less natural composition will also be mentioned. Examples of these include aptamers and

Bone turnover markers and prediction of bone loss in elderly women

Around 70,000 osteoporosis-related fractures occur in Sweden annually and approximately half of the women in western world will sustain a fragility fracture after the age of 50 years. Fracture preventive efforts require the identification of individuals who are at high risk. Biochemical markers of bone turnover (BTMs) have shown some degree of fracture predictability. There is also a correlation b