Lung diseases belong the major causes of death worldwide. Recent innovative methodological developments now allow more and more for the use of primary human tissue and cells to model such diseases. In this regard, the review covers bronchial air-liquid interface cultures, precision cut lung slices as well as ex vivo cultures of explanted peripheral lung tissue and de-/re-cellularization models. Di

While child labour has always been an important part of the industrial revolutionstory, there is little quantitative evidence about the number of child workers in the1740–1850 period. This article estimates trends in the percentage of the agriculturalday-labouring workforce that were children. By using the wage level to identify childworkers, it is possible to estimate child labour for a large sam

This article argues that the Roman poet Ovid in his Metamorphoses invented the apotheosis of Hersilia into the goddess Hora as a way to flatter the empress Livia. There are compelling parallels between the words used to describe Hersilia and Livia in Ovid’s poetry. Furthermore, Hersilia was, according to the legend, a Sabine woman who married Romulus, the founder of Rome. Livia was born into the C

Softwood bark contains a large amounts of extractives—i.e., soluble lipophilic (such as resin acids) and hydrophilic components (phenolic compounds, stilbenes). The effects of the partial removal of water-soluble extractives before acid-catalyzed steam pretreatment on enzymatic digestibility were assessed for two softwood barks—Norway spruce and Scots pine. A simple hot water extraction step remov

The carbon dioxide embodied in Chinese exports to developed countries increased rapidly from 1995 to 2008. We test the extent to which institutional reforms in China can explain this increase. We focus on five areas of reforms: trade liberalization, environmental institutions, legal and property rights, institutional risk and exchange rate policy. Our results show that trade liberalization, weak eThe carbon dioxide embodied in Chinese exports to developed countries increased rapidly from 1995 to 2008. We test the extent to which institutional reforms in China can explain this increase. We focus on five areas of reforms: trade liberalization, environmental institutions, legal and property rights, institutional risk and exchange rate policy. Our results show that trade liberalization, weak e

Nationalekonomiska institutionen delar Finansinspektionens oro för hushållens höga skuldsättning och de negativa effekter dessa kan få på samhällsekonomin i framtiden. Institutionen ställer sig emellertid inte bakom förslaget om ett skärpt amorteringskrav. Hushållens växande skulder är orsakade av låga räntor Amorteringskravet är förvisso en metod för att motverka de låga räntornas effekt på skuld

BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable burden of disease. By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the importance of addressing risks in context.METHODS: We u

BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measure

BACKGROUND: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195

BACKGROUND: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition wit

BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors

BACKGROUND: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016), we measured 37 of the 50 health-relate

Recension av Lennart Pehrson, Historien om Charles A. Lindbergh – från Jesus till Judas.

In this contribution, we elaborate the material force method with application to standard dissipative materials, in particular crystal-(elasto)plasticity. It thereby turns out that material heterogeneities caused by the gradient of the corresponding slip parameters induce additional material volume forces. As a result, we observe that these forces contribute to computations of typical boundary val

The aim of this thesis is to describe how the luminosity can be measured in the ATLAS experiment at the Large Hadron Collider. Luminosity is a fundamental quantity that is used in most physics studies at the LHC. For example in order to measure cross sections. Firstly, the detector description of LUCID which has been implemented in the global ATLAS software framework is described and validated. Se

The purpose of this paper is to perform a detailed examination of corruption effects on trade based on corruption characteristics known to affect economic exchange within the corruption research field. These characteristics are the level, prevalence, customs location, function and predictability of corruption. The multifaceted corruption impact on trade is empirically examined using a corrupti