Sökresultat

Filtyp

Din sökning på "*" gav 531333 sökträffar

The Role of Purposiveness in a Strategic Theory of Organizational Capabilities

Organizational capabilities appear in both the capability-based view and in the resource-based view. Both theories are, to a varying degree, based on notions such as bounded rationality and tacit knowledge, while paying less attention to the aspects of intentionality and purposiveness that are associated with the notion of being capable of something. Based on a case-study of pricing capability in

A Probing Feeding Strategy for Recombinant E. coli Cultivations

*Summary: The bacterium Escherichia coli is a common host organism for recombinant protein production. A problem encountered is the accumulation of the by-product acetate, which tends to reduce growth and protein production (1). Formation of acetate can be avoided by a proper substrate feeding strategy, but most strategies require considerable process knowledge to work well. The main problem is th

The pros and cons of anthropomorphism

Much of the animal ethics and welfare debate today is accused of anthropomorphism, i.e. that human mental states are ascribed to animals. It is generally claimed that these attitudes does no service to animals, since they, according to many natural scientists, usually fail to recognize what animals really are, that animals' needs and responses are actually very different from humans'. The damaging

Thermodynamical Consequences of Strain Softening in Tension

The strain softening behavior of a tension bar loaded by an increasing elongation is analyzed. The constitutive model consists of linear elasticity in combination with associated plasticity theory using a maximum tensile stress criterion as yield surface. The resulting mechanical stability criterion is augmented by considerations of the use of the second law of thermodynamics. These thermodynamica

Distributed Control with Low-Rank Coordination

A common approach to distributed control design is to impose sparsity constraints on the controller structure. Such constraints, however, may greatly complicate the control design procedure. This paper promotes an alternative structure, which is not sparse, yet might nevertheless be well suited for distributed control purposes. The structure appears as the optimal solution to a class of coordinati

A Source-Based Test-Bed for Fast-Neutron Irradiation

The "3He crisis" has resulted in a major effort worldwide to develop replacement neutron-detector technologies. Such technologies are in their infancy and need to be thoroughly tested before becoming mainstream. Neutron sources for controlled irradiation include accelerators, nuclear reactors and radioactive sources. Neutrons produced in nuclear reactors and at accelerators have a very high cost p

DIFFERENT DARLING CONCEPTIONS TIED TO DIFFERENT SOCIETAL SYSTEMS - the case of illegal file sharing in a brave new world

Different societies regulate differently. Historically, social evolution has often been connected to technological innovations. The combustion engine took a central position in what later became known as the industrialized society, an urbanizing era of factories and production, on its hand following on the rural society tied to agriculture and trade. With each type of society comes a specific type

Process Identification through modular neural networks and rule extraction

Monolithic neural networks may be trained from measured data to establish knowledge about the process. Unfortunately, this knowledge is not guaranteed to be found and – if at all – hard to extract. Modular neural networks are better suited for this purpose. Domain-ordered by topology, rule extraction is performed module by module. This has all the benefits of a divide-and-conquer method and opens

Intracellular accumulation of secreted proteoglycans inhibits cationic lipid-mediated gene transfer. Co-transfer of glycosaminoglycans to the nucleus

Molecules secreted by potential target cells may interfere with cationic lipid-mediated gene transfer. This has been studied using human lung fibroblasts and human epidermoid lung cancer cells. Secreted cell medium components caused a substantial decrease both in the uptake of cationic lipid-DNA complexes (2-4-fold) and in reporter gene expression (100-1000-fold). Metabolic labeling of the cell me

Objects as Links Between Person and Place

In a recently conducted interview study, some survivors of traffic victims rate their home as the most important place for remembrance, compared to both the accident site and the burial plot. The reason for this evaluation appears to be the place’s ability to bring about a positive presence of the deceased. Supported by photographs and personal objects, the home serves as a constant reminder, and