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Design and Planning of a Transdisciplinary Investigation into Farmland Pollinators : Rationale, Co-Design, and Lessons Learned

To provide a complete portrayal of the multiple factors negatively impacting insects in agricultural landscapes it is necessary to assess the concurrent incidence, magnitude, and interactions among multiple stressors over substantial biogeographical scales. Trans-national ecological field investigations with wide-ranging stakeholders typically encounter numerous challenges during the design planni

Spatially mutually constrained inversion of hydrogeophysical surveys for water resource interest zone in eastern Denmark

Denmark is currently undertaking extensive groundwater mapping surveys in designated water interest areas. The mapping objectives include vulnerability assessments, delineation of existing aquifers, and localization of new deeper lying aquifers. Airborne electromagnetics are employed for regional mapping to depths of hundreds of meters. Resistivity profiling and pulled-array geo-electrics are utilDenmark is currently undertaking extensive groundwater mapping surveys in designated water interest areas. The mapping objectives include vulnerability assessments, delineation of existing aquifers, and localization of new deeper lying aquifers. Airborne electromagnetics are employed for regional mapping to depths of hundreds of meters. Resistivity profiling and pulled-array geo-electrics are util

Easy cleanups or forbearing improvements : The effect of CEO tenure on successor's performance

Long CEO tenure can harm firm performance even after the CEO is replaced. We analyze this issue by conditioning post-turnover firm performance on the length of the preceding CEO's tenure. Identification comes from instrumenting sudden CEO deaths as an exogenous shock to tenure length. We find that when a successor takes over after a long-tenured CEO, operating performance and stock returns are sig

Biology teachers’ collaborative experiences : benefits and difficulties in different contexts in relation to perceived value

Collaboration has the potential to strengthen both professional learning and well-being for teachers. However, it can also bring problematic aspects, such as increased workload and conflicts. The purpose of this study was to explore biology teachers’ experiences of collaboration to better understand how upper secondary school organisations can support teachers to obtain valuable collaborations. By

Analysis of stresses in aluminum particles embedded inside unidirectional and woven graphite/polyimide composites subjected to large bending loads

The effect of large bending loads on strains and stresses inside aluminum particles embedded in unidirectional and woven eight harness satin (8HS) graphite/PMR-15 composites has been examined. The stresses and strains in the particles were determined by performing X-ray diffraction (XRD) measurements. It has been shown in this work that when the composites are subjected to large four-point bending

The altered drivers of evapotranspiration trends around the recent warming hiatus in China

This study focuses on the trends and the causes of variation in actual evapotranspiration (AET) around the warming hiatus over China by a comprehensive analysis applying various temporal–spatial methods. It is observed that the annual AET showed a different trend around 2000 for China as a whole. By employing segmented regression analysis for detecting warming hiatus points, high temporal inconsis

Bone mass in Saudi women aged 20–40 years : the association with obesity and vitamin D deficiency

Summary: This study describes that low bone density is prevalent in premenopausal Saudi women, especially women of normal weight and vitamin D deficiency. Although BMD is higher in obese young women, this may not be beneficial later in life in conjunction with persistent vitamin D deficiency. Introduction: Not attaining peak bone mass is one crucial factor contributing to the risk of developing os

Site-specific CRISPR-based mitochondrial DNA manipulation is limited by gRNA import

Achieving CRISPR Cas9-based manipulation of mitochondrial DNA (mtDNA) has been a long-standing goal and would be of great relevance for disease modeling and for clinical applications. In this project, we aimed to deliver Cas9 into the mitochondria of human cells and analyzed Cas9-induced mtDNA cleavage and measured the resulting mtDNA depletion with multiplexed qPCR. In initial experiments, we fou

Experimental and theoretical near-edge x-ray-absorption fine-structure studies of NO+

Experimental near-edge x-ray-absorption fine-structure (NEXAFS) spectra of the nitrosonium NO+ ion are presented and theoretically analyzed. While neutral NO has an open shell, the cation is a closed-shell species, which for NEXAFS leads to the simplicity of a closed-shell spectrum. Compared to neutral NO, the electrons in the cation experience a stronger Coulomb potential, which introduces a shif

Individual Genetic Heterogeneity

Genetic variation has been widely covered in literature, however, not from the perspective of an individual in any species. Here, a synthesis of genetic concepts and variations relevant for individual genetic constitution is provided. All the different levels of genetic information and variation are covered, ranging from whether an organism is unmixed or hybrid, has variations in genome, chromosom

Obesity is associated with coronary artery stenosis independently of metabolic risk factors : The population-based SCAPIS study

Background and aims: Previous studies reported divergent results on whether metabolically healthy obesity is associated with increased coronary artery calcium and carotid plaques. We investigated this in a cross-sectional fashion in a large, well-defined, middle-aged population using coronary CT angiography (CCTA) and carotid ultrasound. Methods: In the SCAPIS study (50–65 years, 51% female), CCTA

On the Oxidative Valorization of Lignin to High-Value Chemicals : A Critical Review of Opportunities and Challenges

The efficient valorization of lignin is crucial if we are to replace current petroleum-based feedstock and establish more sustainable and competitive lignocellulosic biorefineries. Pulp and paper mills and second-generation biorefineries produce large quantities of low-value technical lignin as a by-product, which is often combusted on-site for energy recovery. This Review focuses on the conversio

Antiretroviral therapy non-adherence among children living with HIV in Dire Dawa, Eastern Ethiopia : a case-control study

Background: In 2018, nearly 90% of the global children living with human immunodeficiency virus (HIV) were in sub-Saharan Africa (SSA). Compared to the adult population, antiretroviral therapy (ART) coverage among children was limited. However, adherence remained a problem among children though they had limited access to ART. This study was conducted to identify the risk factors of non-adher

Vascular Aging and COVID-19

Vascular age is determined by functional and structural changes in the arterial wall. When measured by its proxy, pulse wave velocity, it has been shown to predict cardiovascular and total mortality. Disconcordance between chronological and vascular age might represent better or worse vascular health. Cell senescence is caused by oxidative stress and sustained cell replication. Senescent cells acq