Sökresultat

Filtyp

Din sökning på "*" gav 528255 sökträffar

Assessment of the TRX2p-yEGFP Biosensor to Monitor the Redox Response of an Industrial Xylose-Fermenting Saccharomyces cerevisiae Strain during Propagation and Fermentation

The commercial production of bioethanol from lignocellulosic biomass such as wheat straw requires utilizing a microorganism that can withstand all the stressors encountered in the process while fermenting all the sugars in the biomass. Therefore, it is essential to develop tools for monitoring and controlling the cellular fitness during both cell propagation and sugar fermentation to ethanol. In t

The National Prevalence of Clinically Diagnosed Psoriatic Arthritis in Sweden in 2017

Objective. Psoriatic arthritis (PsA) prevalence estimates vary across studies; studies based on national data are few. We aimed to estimate the prevalence of clinically diagnosed PsA in Sweden in 2017, overall and stratified by sex, age, education, and geography, and to quantify disease-modifying antirheumatic drug (DMARD) use among those in contact with specialized rheumatology care between 2015

Temperature-driven transition into vortex clusters in low-kappa intertype superconductors

In the vicinity of the type-I/type-II crossover in conventional superconductors, vortices exhibit a nonmonotonic interaction, which leads to exotic vortex matter states. We perform molecular dynamics simulations on a model superconductor in the intertype regime. In a field cooled approach, we examine the transition of a homogeneous vortex lattice (VL) into a structure consisting of VL domains and

Effect of droughts and climate change on future soil weathering rates in Sweden

In a future warmer climate, extremely dry, warm summers might become more common. Soil weathering is affected by temperature and precipitation, and climate change and droughts can therefore affect soil chemistry and plant nutrition. In this study, climate change and drought effects on soil weathering rates and release of Ca, Mg, K and Na were studied on seven forest sites across different climates

Soluble CD163 and glycated haemoglobin were independently associated with the progression of diabetic retinopathy in adult patients with type 1 diabetes

Objective High vitreous levels of soluble (s)CD163 have been demonstrated in severe diabetic retinopathy (DR). The aim of this study was to explore the predictive values of plasma sCD163 and glycated haemoglobin (HbA1c) for DR progression in adults with type 1 diabetes. Methods and analyses The study design was prospective. Fundus photography performed in 2009 and at follow-up (≤12 years later) we

Implementation of the measure of case discussion complexity to guide selection of prostate cancer patients for multidisciplinary team meetings

Background: Multidisciplinary team meetings (MDTMs) provide an integrated team approach to ensure individualized and evidence-based treatment recommendations and best expert advice in cancer care. A growing number of patients and more complex treatment options challenge MDTM resources and evoke needs for case prioritization. In this process, decision aids could provide streamlining and standardize

A reality check on the GARCH-MIDAS volatility models

We employ a battery of model evaluation tests for a broad set of GARCH-MIDAS models and account for data snooping bias. We document that inferences based on standard tests for GM variance components can be misleading. Our data mining free results show that the gain of macro-variables in forecasting total (long-run) variance by GM models is overstated (understated). Estimation of different componen

Burning a holy book: the dilemma of free speech

In recent weeks, Sweden has experienced several Quran-burning incidents. These can reinforce anti-religious discourse and politicised campaigns against religious minorities. They can also put Swedish multicultural harmony at risk. Azher Hameed Qamar argues that we must interpret the laws permitting Quran-burnings as being in the best interest of the people

Probing the structure of χc1 (3872) with photon transition form factors

We propose studying the structure of the χc1(3872) axial vector meson through its γL∗γ→χc1(3872) transition form factor. We derive a light-front wave function representation of the form factor for the lowest cc¯ Fock state. We found that the reduced width of the state is well within the current experimental bound recently published by the Belle Collaboration. This strongly suggests a crucial role

Interaction between plasma phospholipid odd-chain fatty acids and GAD65 autoantibodies on the incidence of adult-onset diabetes : the EPIC-InterAct case–cohort study

Aims/hypothesis: Islet autoimmunity may progress to adult-onset diabetes. We investigated whether circulating odd-chain fatty acids (OCFA) 15:0 and 17:0, which are inversely associated with type 2 diabetes, interact with autoantibodies against GAD65 (GAD65Ab) on the incidence of adult-onset diabetes. Methods: We used the European EPIC-InterAct case–cohort study including 11,124 incident adult-onse

Regulation of human oocyte maturation in vivo during the final maturation of follicles

STUDY QUESTION: Which substances and signal transduction pathways are potentially active downstream to the effect of FSH and LH in the regulation of human oocyte maturation in vivo? SUMMARY ANSWER: The regulation of human oocyte maturation appears to be a multifactorial process in which several different signal transduction pathways are active. WHAT IS KNOWN ALREADY: Many studies in animal species

Institutionalised Dreams : The Art of Managing Foreign Aid

Using examples from Poland, Elżbieta Drążkiewicz explores the question of why states become donors and individuals decide to share their wealth with others through foreign aid. She comes to the conclusion that the concept of foreign aid requires the establishment of a specific moral economy which links national ideologies and local cultures of charitable giving with broader ideas about the global

Brandteknisk dimensionering av träfasader i Br1-byggnader

Brandteknisk dimensionering av träfasader i Br1-byggnader – i teorin och i praktiken Användandet av trä som byggnadsmaterial har ökat eftersom trä är ett mer hållbart material för miljön. För att kunna använda en träfasad för en byggnad i fler än två plan, eller som på annat sätt har ett högre skyddsbehov behöver fasaden klara SP FIRE 105 som är en testmetod för träfasader. Träfasaden byggs däreThis report explores the use of wooden façades in Br1-buildings by identifying and assessing test methods for façades available in Sweden and other European countries. The aim is also to investigate to what extent SP FIRE 105 is being used and how variations made to tested façades are being assessed. The methods used have been a literature study and interview study. The results show that there are

An urban ‘age of timber’? Tensions and contradictions in the low-carbon imaginary of the bioeconomic city

What will the low-carbon cities of tomorrow be made from? We see an unexpected answer today in the return of ‘premodern’/‘preindustrial’ materials to central cities and skylines. Champions of new mass timber materials have driven a race on iconic ‘plyscrapers’ and, increasingly, novel systems of industrial prefabrication. Drawing on the notion of sociotechnical imaginaries, we explore how advocate

Synergistic Fluorine⋅⋅⋅Sulfur Intra- and Intermolecular Interactions on Dopant-Free Hole Transport Material for Efficient and Stable Inverted Perovskite Solar Cells

Designing dopant-free small-molecule hole transport materials (HTMs) with self-assembly behavior via noncovalent interactions is considered as one effective strategy to achieve high-performance inverted perovskite solar cells (PSCs). Herein, two donor-π bridge-donor (D–π–D) HTMs are presented, TPASF and TPAOF, containing 3,6-dimethoxythieno[3,2-b]thiophene as a core part with 3-fluoro-N,N-bis(4-(m

Recombinant factor IX Fc prophylaxis reduces pain and increases levels of physical activity, with sustained, long-term improvements in patients with hemophilia B : post hoc analysis of phase III trials using patient-reported outcomes

Background: Pain is a common symptom of hemophilia that may adversely affect patients’ quality of life (QoL). Previous post hoc analyses of prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) have been published for adults and adolescents, demonstrating improvements in health-related QoL (HRQoL) when assessed by the haemophilia-specific QoL (HaemAQoL) questionnaire. Objective: To des

Vulnerable Victims or Agents of Change? A qualitative content analysis on the representation of women in Nepal's National Adaptation Plan

Climate adaptation policies in Nepal have previously depicted women as vulnerable victims. Policy-makers have described women as a weak and voiceless group that needs “saving” in environmental politics. Several studies have emphasized that these simplistic representations perpetuate gender stereotypes and omit proactive roles in climate action. Recent developments in feminist academia recognize th