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Gaming Activity and Possible Changes in Gaming Behavior Among Young People During the COVID-19 Pandemic : Cross-sectional Online Survey Study

Background: Young people's daily lives and social interactions changed remarkably during the COVID-19 pandemic as schools and cinemas closed, leisure activities were cancelled, and gatherings were regulated. Questions have been raised by the media, schools, policy makers, and research communities about the effect on young people's online behaviors. Objective: This cross-sectional study aimed to st

Higher Education and Research Policies : the current global agenda and implications for international cooperation

International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point

Crystal structure of reduced protein R2 of ribonucleotide reductase : The structural basis for oxygen activation at a dinuclear iron site

Background: Ribonucleotide reductases (RNRs) catalyze the formation of the deoxyribonucleotides that are essential for DNA synthesis. The R2 subunit of Escherichia coli RNR is a homodimer containing one dinuclear iron centre per monomer. A tyrosyl radical is essential for catalysis, and is formed via a reaction in which the reduced, diferrous form of the iron centre activates dioxygen. To help und

Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67

Background: Foot-and-mouth disease viruses (FMDVs) are members of the picornavirus family and cause an economically important disease of cloven-hoofed animals. To understand the structural basis of antigenic variation in FMDV, we have determined the structures of two viruses closely related to strain O1BFS whose structure is known. Results The two new structures are, like O1BFS, both serotype O vi

The contribution of latent factors of executive functioning to mind wandering: : An experience sampling study

Accumulating evidence suggests that individuals with greater executive resources spend less time mind wandering.Independent strands of research further suggest that this association depends on concentration and a guiltydysphoricdaydreaming style. However, it remains unclear whether this association is specific to particular featuresof executive functioning or certain operationalizations of mind wa

Evaluating The Prospects Of Benefit Sharing Schemes In Protecting Mountain Gorillas In Central Africa

Presently, the mountain gorilla in Rwanda, Uganda, and the Democratic Republic of Congo is endangered mainly by poaching and habitat loss. This paper sets out to investigate the possible resolution of poaching involving the local community by using benefit sharing schemes with local communities. Using a bioeconomic model, the paper demonstrates that the current revenue sharing scheme yields subopt

Vertical test results on ESS medium and high beta elliptical cavity prototypes equipped with helium tank

The ESS elliptical superconducting Linac consists of two types of 704.42 MHz cavities, medium and high beta, to accelerate the beam from 216 MeV (spoke cavity Linac) up to the final energy at 2 GeV. The last Linac optimization, called Optimus+[1], has been carried out taking into account the limitations of SRF cavity performance (field emission). The medium and high-beta parts of the Linac are com

Molecular detection and characterization of intestinal and blood parasites in wild chimpanzees (Pan troglodytes verus) in senegal

Wild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal an

Hyperbranched Polyesters Based on Indole- and Lignin-Derived Monomeric Aromatic Aldehydes as Effective Nonionic Antimicrobial Coatings with Excellent Biocompatibility

This research aims to investigate nonionic hyperbranched polyesters (HBPs) derived from indole and lignin resources as new nontoxic antimicrobial coatings. Three nonionic HBPs with zero to two methoxy ether substituents on each benzene ring in the polymer backbones were synthesized by melt-polycondensation of three corresponding AB2 monomers. The molecular structures and thermal properties of the

Mapping the biotic degradation hazard of wood in Europe - Biophysical background, engineering applications, and climate change-induced prospects

Construction using timber has seen a resurgence in light of global climate mitigation policies. Wood is a renewable resource, and engineered wood products are proving to be competitive against concrete and steel while having several advantages. However, while the renewable nature of wood in construction is a beneficial property for climate mitigation policies, the process of biodegradation introdu

Prostate cancer incidence and survival in relation to prostate cancer as second cancer in relatives

OBJECTIVES: To investigate if the risk of prostate cancer (PC) differs based on the order of primary PC diagnosed in first-degree relatives (FDRs) given possibly different risk factors for PC as first primary cancer (PCa-1) and second primary cancer (PCa-2).SUBJECTS AND METHODS: In this Swedish nationwide cohort, PC diagnosis was followed for among 149,985 men with one FDR affected by PCa-1, 10,97

The datafication of pain : : Trials and tribulations in measuring phantom limb pain

This article takes the phenomenon of phantom limb pain (PLP), and a therapeutic technology designed to treat it, as springboards to critically consider a transformation: from deeply subjective experiences into quantitative data. Drawing upon ethnographic fieldwork on neuroprosthetic development, I examine an international clinical trial coordinated in Sweden using neuromuscular activation, machine

Homotopy Continuation for Sensor Networks Self-Calibration

Given a sensor network, TDOA self-calibration aims at simultaneously estimating the positions of receivers and transmitters, and transmitters time offsets. This can be formulated as a system of polynomial equations. Due to the elevated number of unknowns and the nonlinearity of the problem, obtaining an accurate solution efficiently is nontrivial. Previous work has shown that iterative algorithms

Structure and ion-release mechanism of P IB-4-type ATPases

Abstract Transition metals, such as zinc, are essential micronutrients in all organisms, but alsohighly toxic in excessive amounts. Heavy-metal transporting P-type (PIB) ATPases are crucial forhomeostasis, conferring cellular detoxification and redistribution through transport of these ionsacross cellular membranes. No structural information is available for the PIB-4-ATPases, the subclasswith the

Swedish Foreign Policy Feminisms : Women, Capitalism and Social Democracy

This article outlines the historical distinctiveness of the feminist foreign policy (FFP) Sweden has pursued since 2014. To highlight the particularity of the current FFP, we make use of two methodological moves: de-framing and counterpoint. De-framing helps us highlight the importance for the current FFP of a moment in the beginning of the 1990s, when a feminism naturalising capitalist arrangemen

Confocal imaging dataset to assess endothelial cell orientation during extreme glucose conditions

Confocal microscopy offers a mean to extract quantitative data on spatially confined subcellular structures. Here, we provide an imaging dataset of confocal z-stacks on endothelial cells spatially confined on lines with different widths, visualizing the nucleus, F-actin, and zonula occludens-1 (ZO-1), as well as the lines. This dataset also includes confocal images of spatially confined endothelia

Severe infections in patients with ANCA-associated vasculitis treated with rituximab

Objectives: Rituximab (RTX) is an anti-CD20 antibody that selectively depletes B cells and has emerged as a therapy for ANCA-associated vasculitis (AAV) during the past decade. This study sought to quantify and determine potential risk factors for severe infections in AAV patients treated with RTX at rheumatology clinics in Mexico City, Mexico and Lund, Sweden. Methods: The study consisted of a re