Twenty-two molecular diagnostic laboratories from 14 countries participated in a consortium study to estimate the impact of Factor VIII gene inversions in severe hemophilia A. A total of 2,093 patients with severe hemophilia A were studied; of those, 740 (35%) had a type 1 (distal) factor VIII inversion, and 140 (7%) showed a type 2 (proximal) inversion. In 25 cases, the molecular analysis showed

Genetic and family studies have indicated that Graves disease and Hashimoto thyroiditis have a heritable component which appears to be shared to some extend also with some other autoimmune diseases (AIDs). In the present nation-wide study we describe familial risk for Graves disease and Hashimoto thyroiditis identified from the Swedish Hospital Discharge Register (years 1964 through 2012) and the

Om europeisk invandring till USA.

Categorising people and housing situations is unavoidable in research and national and local statistics on homelessness, as well as in regulating and planning for interventions and supply and allocation of suitable accommodation. Despite different motives and original functions, however, these categories and the use of them are influenced by the political discourse, especially when they travel froCategorising people and housing situations is unavoidable in research and national and local statistics on homelessness, as well as in regulating and planning for interventions and supply and allocation of suitable accommodation. Despite different motives and original functions, however, these categories and the use of them are influenced by the political discourse, especially when they travel fro

Biofuels are still too costly to compete in the energy market and it has been suggested that low-value feedstocks could provide an opportunity for the production of low-cost biofuels; however, the lower quality of these feedstocks requires the introduction of a conditioning step in the biorefinery process. The aim of this study was to evaluate whether feedstock savings cover the cost of conditioni

What does the persistent construction of ‘the homeless’ and the revitalised term ‘our homeless’ include, imply, and ex- clude in Swedish political debate? And how is it politically and morally related to other houseless groups in the country? These questions are approached through an analysis of minutes from the Swedish Parliament 2015–2019. Inspired by Simmel’s (1908/1965) definition of ‘the poor

BACKGROUND: Cystic fibrosis (CF), involves excessive airway accumulation of neutrophils, often in parallel with severe infection caused by Pseudomonas aeruginosa. Free histones are known to possess bactericidal properties, but the degree of antibacterial activity exerted on specific lung-based pathogens is largely unknown. Neutrophils have a high content of peptidyl deiminase 4 (PADI4), which citr

We study a scenario where a monitor is interested in the freshest possible update from a remote sensor. The monitor also seeks to minimize the number of updates that exceed a certain freshness threshold, beyond which, the information is deemed to be too old. Previous work has presented results for First Come First Served (FCFS) systems. However, it has been shown that Last Come First Served (LCFS)

OBJECTIVE: To explore dementia management from a primary care physician perspective.DESIGN: One-page seven-item multiple choice questionnaire; free text space for every item; final narrative question of a dementia case story. Inductive explorative grounded theory analysis. Derived results in cluster analyses. Appropriateness of dementia drugs assessed by tertiary care specialist.SETTING: Twenty-fi

OBJECTIVES: To explore staff experiences of working with a digital communication platform implemented throughout several primary healthcare centres in Sweden.DESIGN: A descriptive qualitative approach using focus group interviews. Qualitative content analysis was used to code, categorise and thematise data.SETTING: Primary healthcare centres across Sweden, in both rural and urban settings.PARTICIP

Eye trackers are sometimes used to study the miniature eye movements such as drift that occur while observers fixate a static location on a screen. Specifically, analysis of such eye-tracking data can be performed by examining the temporal spectrum composition of the recorded gaze position signal, allowing to assess its color. However, not only rotations of the eyeball but also filters in the eye

Due to its reported high sampling frequency and precision, the Tobii Pro Spectrum is of potential interest to researchers who want to study small eye movements during fixation. We test how suitable the Tobii Pro Spectrum is for research on microsaccades by computing data-quality measures and common properties of microsaccades and comparing these to the currently most used system in this field: the

Meetings are common in contemporary working life, but they are often overlooked in academic studies and sometimes defined as empty or boring by employees. Yet, the meeting society isbeing reproduced again and again. There seem to be hidden ways to incorporate meetings into today’s working life without arousing critique about pointless activities and deviations from what should really be done. One

Political Parties, Enfranchisement, and Citizenship: Debates on Voting Rights for Expatriate Citizens and Resident Aliens in the Swedish Parliament after 1921.The question of how voting rights should be designed in relation to national citizenship has gained attention in modern, academic debates. However, there are few empirical studies on the political agents actually involved in efforts to promo

BACKGROUND: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative f